Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Zhongping Cheng"'
Autor:
Yaoqi Sun, Bing Xiong, Xueqian Shuai, Jiale Li, Chunyan Wang, Jing Guo, Zhongping Cheng, Shupeng Liu
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Immunotherapies effectively treat human malignancies, but the low response and resistance are major obstacles. Neoantigen is an emerging target for tumor immunotherapy that can enhance anti-tumor immunity and improve immunotherapy
Externí odkaz:
https://doaj.org/article/39c966b21a2d41db9c1b36e6a360c9d9
Autor:
Jing Guo, Chunyan Wang, Ning Luo, Yuliang Wu, Wei Huang, Jihui Zhu, Weihui Shi, Jinye Ding, Yao Ge, Chunhong Liu, Zhen Lu, Robert C. Bast, Guihai Ai, Weihong Yang, Rui Wang, Caixia Li, Rong Chen, Shupeng Liu, Huajun Jin, Binghui Zhao, Zhongping Cheng
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinical and clinical studie
Externí odkaz:
https://doaj.org/article/47172d00ce154c1d97952eab624ecce7
Autor:
Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation. One of the hormone receptors contributing to endo
Externí odkaz:
https://doaj.org/article/1dbb22213ddc43528911c90156f44bbb
Autor:
Lian Wang, Bing Xiong, Wei Lu, Yujie Cheng, Jihui Zhu, Guihai Ai, Xiaojie Zhang, Xiuni Liu, Zhongping Cheng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116474- (2024)
Chemotherapy and targeted drugs-induced senescent ovarian cancer cells that accumulate in peritoneal adipose tissue contribute significantly to chronic inflammation, disrupt homeostasis, and may fuel various aspects of cancer progression. However, th
Externí odkaz:
https://doaj.org/article/21ac9a1330c94d1c81f8b37010bbc5d6
Autor:
Yuliang Wu, Qi Liu, Yan Xie, Jihui Zhu, Sai Zhang, Yao Ge, Jing Guo, Ning Luo, Wei Huang, Runping Xu, Shupeng Liu, Zhongping Cheng
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background MUC16 (CA125) is a commonly used tumor marker for ovarian cancer screening and reported to be an immunosuppressive factor by acting on the sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on the surface of natural kille
Externí odkaz:
https://doaj.org/article/8ea840ba02b241169e086f2ccd11ffa2
Identification of TRPM2 as a prognostic factor correlated with immune infiltration in ovarian cancer
Autor:
Wei Huang, Yuliang Wu, Ning Luo, Xueqian Shuai, Jing Guo, Chunyan Wang, Fanchun Yang, Li Liu, Shupeng Liu, Zhongping Cheng
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Introduction Ovarian cancer (OC) is one of the most common gynecologic malignant cancers with the current survival rate remaining low. TRPM2 has been reported as a survival predictor in various cancers but not in OC. The aim of this study is
Externí odkaz:
https://doaj.org/article/32d57b3fc4ac40beb60ad9587eed80f4
Autor:
Li Liu, Biting Liu, Lian Wang, Caixia Li, Yang Zhou, Jihui Zhu, Jinye Ding, Shupeng Liu, Zhongping Cheng
Publikováno v:
Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-7 (2023)
Abstract Efficient evaluation of the primordial follicle pool (PFP) of mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a gene signature including Sohlh1,
Externí odkaz:
https://doaj.org/article/0fdb0af61b104d65ad59820a128a2846
Autor:
Guihai Ai, Meng Meng, Jing Guo, Caixia Li, Jihui Zhu, Li Liu, Biting Liu, Wenhan Yang, Xiaowen Shao, Zhongping Cheng, Lian Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used treatment to improve h
Externí odkaz:
https://doaj.org/article/f1f88c862bbb470cb7e74631d6f52f15
Publikováno v:
Gynecology and Minimally Invasive Therapy, Vol 12, Iss 3, Pp 141-147 (2023)
Objectives: The treatment of advanced and recurrent gynecological cancers (ARGCs) remains more difficult evens. This assay aims to introduce the application of minimally invasive surgery-multidisciplinary team (MIS-MDT) as well as a comprehensive eva
Externí odkaz:
https://doaj.org/article/8da144b305c04460903bef4f492b1f0a
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-15 (2022)
Abstract Background Aberrant DNA replication is the main source of genomic instability that leads to tumorigenesis and progression. MCM2, a core subunit of eukaryotic helicase, plays a vital role in DNA replication. The dysfunction of MCM2 results in
Externí odkaz:
https://doaj.org/article/1afbe7c88b5d4ca1b15880951b835ae2