Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Zhongpeng Lu"'
1
Akademický článek
Trolline Ameliorates Liver Fibrosis by Inhibiting the NF-κB Pathway, Promoting HSC Apoptosis and Suppressing Autophagy
Autor: Facheng Bai, Quanfang Huang, Jinlan Nie, Shengjuan Lu, Chunyuan Lu, Xunshuai Zhu, Yuxin Wang, Lang Zhuo, Zhongpeng Lu, Xing Lin
Publikováno v: Cellular Physiology and Biochemistry, Vol 44, Iss 2, Pp 436-446 (2017)
Background/Aims: Previous studies have shown that trolline possesses various forms of pharmacological activity, including antibacterial and antiviral potency. The present paper addressed the putative hepatoprotective effects of trolline. Methods: Rat
Externí odkaz: https://doaj.org/article/279120965e2d46889bc46ac24c1cd25b
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2
Akademický článek
Didymin Alleviates Hepatic Fibrosis Through Inhibiting ERK and PI3K/Akt Pathways via Regulation of Raf Kinase Inhibitor Protein
Autor: Xing Lin, Faicheng Bai, Jinlan Nie, Shengjuan Lu, Chunyuang Lu, Xunshuai Zhu, Jinbin Wei, Zhongpeng Lu, Quanfang Huang
Publikováno v: Cellular Physiology and Biochemistry, Vol 40, Iss 6, Pp 1422-1432 (2016)
Background: Didymin has been reported to have anti-cancer potential. However, the effect of didymin on liver fibrosis remains illdefined. Methods: Hepatic fibrosis was induced by CCl4 in rats. The effects of didymin on liver pathology and collagen ac
Externí odkaz: https://doaj.org/article/1ba163b859e54be4b89af8b292ff91f8
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3
Akademický článek
Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-κB activation
Autor: Yan Li, Yongmei Zeng, Quanfang Huang, Shujuan Wen, Yuanyuan Wei, Ya Chen, Xiaolin Zhang, Facheng Bai, Zhongpeng Lu, Jinbin Wei, Xing Lin
Publikováno v: Biomedicine & Pharmacotherapy, Vol 119, Iss , Pp - (2019)
Acute liver injury is a life-threatening syndrome that often caused by hepatocyte damage and is characterized by inflammatory and oxidative responses. Helenalin isolated from Centipeda minima (HCM) has been found to have anti-inflammatory and anti-o
Externí odkaz: https://doaj.org/article/0233d1a3647c493b861d4cf04da1fec0
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4
Akademický článek
Raf Kinase Inhibitory Protein Down-Expression Exacerbates Hepatic Fibrosis In Vivo and In Vitro
Autor: Quanfang Huang, Chunhong Liang, Ling Wei, Jinlan Nie, Shengjuan Lu, Chunyuan Lu, Lang Zhuo, Zhongpeng Lu, Xing Lin
Publikováno v: Cellular Physiology and Biochemistry, Vol 40, Iss 1-2, Pp 49-61 (2016)
Background/Aims: Raf kinase inhibitory protein (RKIP) is closely associated with numerous tumors and participates in their development through regulating the growth, apoptosis, invasion and metastasis of tumor cells. However, the role of RKIP in chro
Externí odkaz: https://doaj.org/article/c6f69c2541a44650baf4164749cad67a
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5
Akademický článek
Contribution of dysferlin deficiency to skeletal muscle pathology in asymptomatic and severe dystroglycanopathy models: generation of a new model for Fukuyama congenital muscular dystrophy.
Autor: Motoi Kanagawa, Zhongpeng Lu, Chiyomi Ito, Chie Matsuda, Katsuya Miyake, Tatsushi Toda
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e106721 (2014)
Defects in dystroglycan glycosylation are associated with a group of muscular dystrophies, termed dystroglycanopathies, that include Fukuyama congenital muscular dystrophy (FCMD). It is widely believed that abnormal glycosylation of dystroglycan lead
Externí odkaz: https://doaj.org/article/c73c1d1fd80a487a8d5eaf3e138f2643
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7
Retracted: Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K /Akt/ mTOR and NF‐κB signalling pathways
Autor: Xing Lin, Yan Li, Shujuan Wen, Quanfang Huang, Zhongpeng Lu, Jinbin Wei, Xiaoling Zhang, Yuanyuan Wei
Publikováno v: Cell Biochemistry and Function. 39:77-87
The present study was to investigate the inhibitory effect and underlying mechanism of Tormentic acid (TA) on hepatic stellate cells (HSCs). HSC-T6 cells were stimulated with Platelet-derived growth factor-BB (PDGF-BB) and TA, and then cell prolifera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed72b7dac1735eaa6872da0f86539a14
https://doi.org/10.1002/cbf.3564
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8
Generation of a Fully Human scFv that binds Tumor-Specific Glycoforms
Autor: Catherin C. Yin, Kalika Kamat, Nathalie Scholler, Zhongpeng Lu, Blake P. Johnson, Karen L. Abbott
Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Tumor-specific glycosylation changes are an attractive target for the development of diagnostic and therapeutic applications. Periostin is a glycoprotein with high expression in many tumors of epithelial origin including ovarian cancer. Strategies to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014f5ff4ffa8aa175a764b0ef97e0ac0
http://link.springer.com/article/10.1038/s41598-019-41567-6
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10
Retracted : Role of RKIP in human hepatic stellate cell proliferation, invasion, and metastasis
Autor: Yuanyuan Wei, Ling Wei, Shujuan Wen, Shimei Tan, Quanfang Huang, Jinbin Wei, Facheng Bai, Zhongpeng Lu, Xiaolin Zhang, Xing Lin
Publikováno v: Journal of Cellular Biochemistry. 120:6168-6177
The purpose of this study was to investigate the effect of Raf kinase inhibitor protein (RKIP) on the growth, apoptosis, invasion, and metastasis of human hepatic stellate cell line (LX-2). A recombinant plasmid (pcDNA3.1-RKIP) or RKIP-targeting smal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::681245432ebb560b8311312f326db820
https://doi.org/10.1002/jcb.27904
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