Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Zhongming Ge"'
Autor:
Yang He, Xiulin Zhang, Xiaolu Zhang, Bo Fu, Jin Xing, Rui Fu, Jianyi Lv, Meng Guo, Xueyun Huo, Xin Liu, Jing Lu, Lixue Cao, Xiaoyan Du, Zhongming Ge, Zhenwen Chen, Xuancheng Lu, Changlong Li
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Helicobacter pylori is a microaerophilic Gram-negative bacterium that resides in the human stomach and is classified as a class I carcinogen for gastric cancer. Numerous studies have demonstrated that H. pylori infection plays a role in regu
Externí odkaz:
https://doaj.org/article/33f56df457df4c68b2394005573c1edb
Autor:
Sureshkumar Muthupalani, Damodaran Annamalai, Yan Feng, Suresh M. Ganesan, Zhongming Ge, Mark T. Whary, Hiroshi Nakagawa, Anil K. Rustgi, Timothy C. Wang, James G. Fox
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Chronic inflammation is integral to the development of esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC), although the latter has not been associated with reflux esophagitis. The L2-IL-1β transgenic mice, express
Externí odkaz:
https://doaj.org/article/0af10e9a26bd4833b248f2606b9d7ca3
Autor:
Nianshuang Li, Xinbo Xu, Yuan Zhan, Xiao Fei, Yaobin Ouyang, Pan Zheng, Yanan Zhou, Cong He, Chuan Xie, Yi Hu, Junbo Hong, Nonghua Lu, Zhongming Ge, Yin Zhu
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTH. pylori infection is the strongest known risk factor for gastric carcinoma. The activation of the yes-associated protein 1 (YAP) and β-catenin pathways has been associated with multiple tumor types. In this study, we investigated the cross
Externí odkaz:
https://doaj.org/article/8a68aaf535a84227bf3d6dc2f83eb191
Autor:
Nianshuang Li, Yan Feng, Yi Hu, Cong He, Chuan Xie, Yaobin Ouyang, Stephen C. Artim, Deqiang Huang, Yin Zhu, Zhijun Luo, Zhongming Ge, Nonghua Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/9dd326b6b0ba4c93be52b3e65d8e73d0
Autor:
Xinbo Xu, Chunxi Shu, Xidong Wu, Yaobin Ouyang, Hong Cheng, Yanan Zhou, Huan Wang, Cong He, Chuan Xie, Xingxing He, Junbo Hong, Nonghua Lu, Zhongming Ge, Yin Zhu, Nianshuang Li
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundHelicobacter pylori infection is the strongest known risk factor for gastric cancer. The Hippo signaling pathway controls organ size and maintains tissue homeostasis by coordinately regulating cell growth and proliferation. Here, we demonst
Externí odkaz:
https://doaj.org/article/8266b6cbd30c42ed9db2c0cea35318a8
Autor:
Zhongming Ge, Sebastian E. Carrasco, Yan Feng, Vasudevan Bakthavatchalu, Damodaran Annamalai, Robin Kramer, Sureshkumar Muthupalani, James G. Fox
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1814-1823 (2020)
ABSTRACTInclusion body nephropathy (IBN) and kidney fibrosis in aged immunodeficient mice and, to lesser extent, in immunocompetent mice have been recently linked to infection of mouse kidney parvovirus (MKPV), also known as murine chapparvovirus (Mu
Externí odkaz:
https://doaj.org/article/b1a193be5b8d4b45a35db8ed16ff91bf
Autor:
Nianshuang Li, Yan Feng, Yi Hu, Cong He, Chuan Xie, Yaobin Ouyang, Stephen C. Artim, Deqiang Huang, Yin Zhu, Zhijun Luo, Zhongming Ge, Nonghua Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-15 (2018)
Abstract Background Helicobacter pylori (H. pylori) delivers oncoprotein CagA into gastric epithelial cells via the T4SS and drives activation of multiple oncogenic signalling pathways. YAP, a core effector of the Hippo tumour suppressor pathway, is
Externí odkaz:
https://doaj.org/article/07633e0300954ab4a42d42c578fe69f0
Publikováno v:
EBioMedicine, Vol 12, Iss C, Pp 247-254 (2016)
Emerging evidence suggests that Helicobacter pylori infection is associated with insulin resistance (IR) yet the underlying mechanisms are still obscure. The vital role of gut microbiota in triggering IR has been increasingly reported, however, no st
Externí odkaz:
https://doaj.org/article/de8c7f70120c4398b307d1c141de2e89
Autor:
Vasudevan Bakthavatchalu, Katherine J Wert, Yan Feng, Anthony Mannion, Zhongming Ge, Alexis Garcia, Kathleen E Scott, Tyler J Caron, Carolyn M Madden, Johanne T Jacobsen, Gabriel Victora, Rudolf Jaenisch, James G Fox
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194443 (2018)
Immune-compromised mouse models allow for testing the preclinical efficacy of human cell transplantations and gene therapy strategies before moving forward to clinical trials. However, CRISPR/Cas9 gene editing of the Wsh/Wsh mouse strain to create an
Externí odkaz:
https://doaj.org/article/b69d9562975649f5956ce47966a81b10
Autor:
Monika Burns, Aldo Amaya, Caroline Bodi, Zhongming Ge, Vasudevan Bakthavatchalu, Kathleen Ennis, Timothy C Wang, Michael Georgieff, James G Fox
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173108 (2017)
Helicobacter pylori (H.pylori), a bacterial pathogen, is a causative agent of gastritis and peptic ulcer disease and is a strong risk factor for development of gastric cancer. Environmental conditions, such as poor dietary iron resulting in iron defi
Externí odkaz:
https://doaj.org/article/8503334b24b64e2fbdceb8a9d6edb14f