Presynaptic Mitochondrial Volume and Density Scale with Presynaptic Power Demand

Autor: Karlis A. Justs, Zhongmin Lu, Amit K. Chouhan, Jolanta A. Borycz, Zhiyuan Lu, Ian A. Meinertzhagen, Gregory T. Macleod

Stable neural function requires an energy supply that can meet the intense episodic power demands of neuronal activity. The bioenergetic machinery of glycolysis and oxidative phosphorylation is highly responsive to such demands, but it must occupy a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb1c5fe2df0f671cdab53a21726522c7
https://doi.org/10.1101/2021.06.17.448756

Transcriptomic Analyses of Inner Ear Sensory Epithelia in Zebrafish

Autor: Zhongmin Lu, Steven Denyer, Gaurav K. Varshney, Lingyu Wang, Denise Yan, Rahul Mittal, Xue Zhong Liu, Teresa Requena, Qi Yao, Kaili Liu, Michael T. Richmond

Publikováno v: Yao, Q, Wang, L, Mittal, R, Yan, D, Richmond, MT, Denyer, S, Requena Navarro, T, Liu, K, Varshney, GK, Lu, Z & Liu, XZ 2020, ' Transcriptomic Analyses of Inner Ear Sensory Epithelia in Zebrafish ', Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, vol. 303, no. 3 . https://doi.org/10.1002/ar.24331
Anat Rec (Hoboken)

Analysis of gene expression has the potential to assist in the understanding of multiple cellular processes including proliferation, cell-fate specification, senesence, and activity in both healthy and disease states. Zebrafish model has been increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782d1be7af21b9fbc1bbed4510000cb5
https://www.pure.ed.ac.uk/ws/files/139106075/Transcriptomic_Analyses_of_Inner_Ear_Sensory_Epithelia_in_Zebrafish_.pdf

Presynaptic Mitochondrial Volume and Packing Density Scale with Presynaptic Power Demand.

Autor: Justs, Karlis A., Zhongmin Lu, Chouhan, Amit K., Borycz, Jolanta A., Zhiyuan Lu, Meinertzhagen, Ian A., Macleod, Gregory T.

Publikováno v: Journal of Neuroscience; 2/9/2022, Vol. 42 Issue 6, p954-967, 14p

ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice

Autor: Oscar Diaz-Horta, Mustafa Tekin, Xue Zhong Liu, Zhongmin Lu, Guney Bademci, Joseph Foster, Levent Sennaroglu, Suna Tokgoz-Yilmaz, Yasuhiro Minami, Benjamin Currall, Clemer Abad, F. Basak Cengiz, Michiru Nishita, Alexandra A. DeSmidt, Faiqa Imtiaz, M'hamed Grati, Cynthia C. Morton, Suat Fitoz, Katherina Walz, Duygu Duman, Amjad Farooq

Publikováno v: Diaz-Horta, O, Abad, C, Sennaroglu, L, Ii, J F, DeSmidt, A, Bademci, G, Tokgoz-Yilmaz, S, Duman, D, Cengiz, F B, Grati, MH, Fitoz, S, Liu, X Z, Farooq, A, Imtiaz, F, Currall, B B, Morton, C, Nishita, M, Minami, Y, Lu, Z, Walz, K & Tekin, M 2016, ' ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice ', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 21, pp. 5993-5998 . https://doi.org/10.1073/pnas.1522512113

Hair cells of the inner ear, the mechanosensory receptors, convert sound waves into neural signals that are passed to the brain via the auditory nerve. Little is known about the molecular mechanisms that govern the development of hair cell-neuronal c

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https://doi.org/10.1073/pnas.1522512113

Zebrafish Model for Nonsyndromic X-Linked Sensorineural Deafness, DFNX1

Autor: Rahul Mittal, Zhongmin Lu, Xue Zhong Liu, Michael T. Richmond, Denise Yan, Steven Denyer, M'hamed Grati, Qi Yao, Alexandra A. DeSmidt, Bing Zou

Publikováno v: Anatomical record (Hoboken, N.J. : 2007)LITERATURE CITED. 303(3)

Hereditary deafness is often a neurosensory disorder and affects the quality of life of humans. Only three X-linked genes (POU class 3 homeobox 4 (POU3F4), phosphoribosyl pyrophosphate synthetase 1 (PRPS1), and small muscle protein X-linked (SMPX)) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b3def9e2a75bd120429f5f92290e9c
https://pubmed.ncbi.nlm.nih.gov/30874365