Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Zhongmei, Zhang"'
Autor:
Meijie Tian, Jun S. Wei, Adam Tai-Chi Cheuk, David Milewski, Zhongmei Zhang, Yong Yean Kim, Hsien-Chao Chou, Can Liu, Sherif Badr, Eleanor G. Pope, Abdelrahman Rahmy, Jerry T. Wu, Michael C. Kelly, Xinyu Wen, Javed Khan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chimeric antigen receptor (CAR) T-cells targeting Fibroblast Growth Factor Receptor 4 (FGFR4), a highly expressed surface tyrosine receptor in rhabdomyosarcoma (RMS), are already in the clinical phase of development, but tumour heterogeneity
Externí odkaz:
https://doaj.org/article/a3964d3bf8e04e298aea51cf07822727
Autor:
Badr, Mohamed Elsherif1 sherif.badr@nih.gov, Zhongmei Zhang1, Xuguang Tai1, Singer, Alfred1 singera@nih.gov
Publikováno v:
Science. 11/3/2023, Vol. 382 Issue 6670, p534-541. 8p. 1 Color Photograph, 4 Diagrams.
Autor:
Meijie Tian, Adam T. Cheuk, Jun S. Wei, Abdalla Abdelmaksoud, Hsien-Chao Chou, David Milewski, Michael C. Kelly, Young K. Song, Christopher M. Dower, Nan Li, Haiying Qin, Yong Yean Kim, Jerry T. Wu, Xinyu Wen, Mehdi Benzaoui, Katherine E. Masih, Xiaolin Wu, Zhongmei Zhang, Sherif Badr, Naomi Taylor, Brad St. Croix, Mitchell Ho, Javed Khan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Chimeric antigen receptor (CAR) T cell therapies targeting single antigens have performed poorly in clinical trials for solid tumors due to heterogenous expression of tumor-associated antigens (TAAs), limited T cell persistence, and T cell exhaustion
Externí odkaz:
https://doaj.org/article/114fac18c13d4632b85c061e52d66443
Publikováno v:
IEEE Access, Vol 7, Pp 89-98 (2019)
The dynamic interventions among sensor streams bring new challenges for the Internet of Things applications to derive meaningful information from a large amount of sensor streams. This paper proposes a declarative service-based method for capturing m
Externí odkaz:
https://doaj.org/article/fbf69aecee7a4c9d850de2ec141cc661
Autor:
Xuguang Tai, Alyssa Indart, Mirelle Rojano, Jie Guo, Nicolai Apenes, Tejas Kadakia, Marco Craveiro, Amala Alag, Ruth Etzensperger, Mohamed Elsherif Badr, Flora Zhang, Zhongmei Zhang, Jie Mu, Terry Guinter, Assiatu Crossman, Larry Granger, Susan Sharrow, Xuyu Zhou, Alfred Singer
Publikováno v:
Nature Immunology. 24:637-651
Thymocytes bearing autoreactive T cell receptors (TCRs) are agonist-signaled by TCR/co-stimulatory molecules to either undergo clonal deletion or to differentiate into specialized regulatory T (Treg) or effector T (Teff) CD4+ cells. How these differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::097f7f9677884eec529ab211ea56cfe5
https://doi.org/10.1038/s41590-023-01469-2
https://doi.org/10.1038/s41590-023-01469-2
Autor:
Zhongmei Zhang, Xuyu Zhou
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Regulatory T cells (Tregs) are small subsets of CD4 T cells that play a central role in the controlling of immune tolerance. Tregs are either generated in the thymus (tTregs) or the periphery (pTregs), and both express the master transcription factor
Externí odkaz:
https://doaj.org/article/90b8fa4f7ea64b3592ab7cca915e7d3f
Autor:
Huang Huang, Xiangmin Hua, Xidan Pang, Zhongmei Zhang, Jingyi Ren, Jiasen Cheng, Yanping Fu, Xueqiong Xiao, Yang Lin, Tao Chen, Bo Li, Huiquan Liu, Daohong Jiang, Jiatao Xie
Publikováno v:
Journal of Virology. 97
Fungal segmented negative-sense RNA viruses (SNSRVs) have been frequently found. Only the large segment encoding RNA-dependent RNA polymerase (RdRp) has been reported in most fungal SNSRVs, except for a few fungal SNSRVs reported to encode nucleocaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e8b95f528bbf1d0abbcb21e9b4bf4a
https://doi.org/10.1128/jvi.01381-22
https://doi.org/10.1128/jvi.01381-22
Publikováno v:
Mobile Information Systems, Vol 2021 (2021)
With the fast development of Sensor Network, Internet of Things, mobile devices, and pervasive computing, enormous amounts of sensor devices are deployed in physical world. Data streams produced by these sensor devices, deployed broadly, can be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b8c75ace2680961d863afe10d8ce52
https://doi.org/10.1155/2021/2502083
https://doi.org/10.1155/2021/2502083
Autor:
Meijie Tian, Jun S. Wei, Adam Cheuk, David Milewski, Zhongmei Zhang, Yong Yuan Kim, Can Liu, Sherif Badr, Michael C. Kelly, Jerry T. Wu, Abdelrahman Rahmy, Hsien-Chao Chou, Xinyu Wen, Javed Khan
Publikováno v:
Cancer Research. 83:1784-1784
Background Chimeric antigen receptor T cells (CAR T) are potential therapies for rhabdosarcoma (RMS), the most common soft tissue sarcoma in children, where patients with relapsed or refractory disease have a dismal cure rate, and effective therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aa26a2c46a09506bebd98b0d3eb2841
https://doi.org/10.1158/1538-7445.am2023-1784
https://doi.org/10.1158/1538-7445.am2023-1784
Autor:
Tanyu Hu, Krung Phiwpan, Jitao Guo, Wei Zhang, Jie Guo, Zhongmei Zhang, Mangge Zou, Xuejie Zhang, Jianhua Zhang, Xuyu Zhou
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158432 (2016)
Wnt/β-catenin signaling pathway plays essential roles in mammalian development and tissue homeostasis. MicroRNAs (miRNAs) are a class of regulators involved in modulating this pathway. In this study, we screened miRNAs regulating Wnt/β-catenin sign
Externí odkaz:
https://doaj.org/article/65483ee34dfc4e9dad3ccda571949fa5