Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zhongling Cai"'
Autor:
Michael N. Edmonson, Sheila A. Shurtleff, Erin Hedlund, John Easton, Xueyuan Cao, Guangchun Song, Jeffery M. Klco, Heather L. Mulder, Konstanze Döhner, Li Dong, Yu Liu, Robert Huether, Yongjin Li, Jinghui Zhang, Jeffrey E. Rubnitz, Zhongling Cai, Hartmut Döhner, Kristy Boggs, Evan Parganas, Richard K. Wilson, Joy Nakitandwe, Lucinda Fulton, Tanja A. Gruber, Ina Radtke, Peter Paschka, Elaine R. Mardis, Ching-Hon Pui, Bhavin Vadodaria, Jinjun Cheng, Li Ding, Michael Rusch, Donald Yergeau, James R. Downing, Lars Bullinger, Xiang Chen, Amanda Larson Gedman, Jyh Rong Chao, Jianmin Wang, Stanley Pounds, Anna Andersson, Robert S. Fulton, Gang Wu, Charles G. Mullighan, Jing Ma, Richard F. Schlenk, Michael P. Walsh, Jinjun Dang, Chunxu Qu, Zachary J Faber
Publikováno v:
Nature genetics. 48(12)
Acute myeloid leukemia (AML) comprises a heterogeneous group of leukemias frequently defined by recurrent cytogenetic abnormalities, including rearrangements involving subunits of the core-binding factor (CBF) transcriptional complex. To better under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4046d19ac05fab0382da28ed01ed3e14
https://pubmed.ncbi.nlm.nih.gov/27798625
https://pubmed.ncbi.nlm.nih.gov/27798625
Autor:
James R. Downing, John D. Schuetz, Andrew Lemoff, Raul C. Ribeiro, Stanley Pounds, Charles G. Mullighan, Ina Radtke, Zhongling Cai, Bing Yan, Anna Andersson, Jeffrey E. Rubnitz, David W Miller, Sheila A. Shurtleff, John Lynch, Jinghui Zhang, Brenda A. Schulman, Susana C. Raimondi
Publikováno v:
Leukemia. 25:1570-1577
To investigate the frequency of isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) mutations in pediatric acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL), we sequenced these genes in diagnostic samples from 515 patients (227 AMLs and 288 A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b736fc401ba28f94c6b6da5f0bdf92f4
https://doi.org/10.1038/leu.2011.133
https://doi.org/10.1038/leu.2011.133
Autor:
Jinghui Zhang, Masami Ishii, Salil Goorha, Guangchun Song, Xueyuan Cao, Susana C. Raimondi, Charles G. Mullighan, Jinjun Cheng, Ina Radtke, Ramapriya Ganti, Jing Ma, Sheila A. Shurtleff, James R. Downing, Xiaoping Su, Jianling Armstrong, Raul C. Ribeiro, Stanley Pounds, Zhongling Cai, Caroline Obert, Jeffrey E. Rubnitz
Publikováno v:
Proceedings of the National Academy of Sciences. 106:12944-12949
Pediatric de novo acute myeloid leukemia (AML) is an aggressive malignancy with current therapy resulting in cure rates of only 60%. To better understand the cause of the marked heterogeneity in therapeutic response and to identify new prognostic mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e3997fba07ae56232e3ff99b51581c
https://doi.org/10.1073/pnas.0903142106
https://doi.org/10.1073/pnas.0903142106
Autor:
Bhavin Vadordaria, Lei Wei, Tanja A. Gruber, Jared Becksfort, Jing Ma, Matthew Parker, Richard W. Kriwacki, Sheila A. Shurtleff, Robert Huether, Kristy Boggs, Li Dong, Gerard P. Zambetti, Li Ding, James R. Downing, Gang Wu, Amanda Larson Gedman, Guangchun Song, Michael Walsh, Gordon Lemmon, Richard J. Gilbertson, Janet F. Partridge, Donald Yergeau, Jinghui Zhang, David W. Ellison, Charles G. Mullighan, Michael Rusch, Richard K. Wilson, Heather L. Mulder, Catherine Weber, Xiang Chen, Suzanne J. Baker, Jinjun Cheng, Zhongling Cai, Erin Hedlund, John Easton, Michael N. Edmonson, Elaine R. Mardis, Jinjun Dang, Zachary J Faber
Studies of paediatric cancers have shown a high frequency of mutation across epigenetic regulators. Here we sequence 633 genes, encoding the majority of known epigenetic regulatory proteins, in over 1,000 paediatric tumours to define the landscape of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc83d271da3f7ab99db04dd3382461f
https://europepmc.org/articles/PMC4119022/
https://europepmc.org/articles/PMC4119022/
Publikováno v:
Weed Technology. 6:104-107
Chinese milkvetch is the most important green manure crop in the rice producing regions of China. The tolerance of Chinese milkvetch to 29 herbicides approved for other legume crops was determined in the greenhouse. Chinese milkvetch was tolerant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8c9916fd96d527f832386dbc371bece
https://doi.org/10.1017/s0890037x00034370
https://doi.org/10.1017/s0890037x00034370
Autor:
Elaine Dzierzak, Xiaoqian Ma, Marella F. T. R. de Bruijn, Tanya Luteijn, Bjorn R. Dortland, Zhongling Cai, James R. Downing
Publikováno v:
Immunity, 13, 423-431. Cell Press
The AML1:CBFβ transcription factor complex is essential for definitive hematopoiesis. Null mutations in mouse AML1 result in midgestational lethality with a complete lack of fetal liver hematopoiesis. While the cell autonomous nature and expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c63723330e383de6d8e97fbca1a3eb
https://pure.eur.nl/en/publications/49daed4f-11d4-4a4d-80cc-084d5ad7e8c7
https://pure.eur.nl/en/publications/49daed4f-11d4-4a4d-80cc-084d5ad7e8c7
Autor:
Chuhl Joo Lyu, Jan M. van Deursen, Zhongling Cai, Noel Lenny, Tsukasa Okuda, James R. Downing, Hironori Harada, Shouli Yang
Publikováno v:
Blood. 91(9)
The t(8;21)-encoded AML1-ETO chimeric product is believed to be causally involved in up to 15% of acute myelogenous leukemias through an as yet unknown mechanism. To directly investigate the role of AML1-ETO in leukemogenesis, we used gene targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ce4a298a7a805eb7cc200285130f70
https://pubmed.ncbi.nlm.nih.gov/9558367
https://pubmed.ncbi.nlm.nih.gov/9558367
Autor:
Charles G. Mullighan, Jing Ma, Letha A. Phillips, James R. Downing, Lynda J. Campbell, Xiaoping Su, Jinghui Zhang, Deborah L. White, Zhongling Cai, Andrew W. Roberts, Sheila A. Shurtleff, Ina Radtke, Timothy P. Hughes
Publikováno v:
Blood. 112:1089-1089
Expression of BCR-ABL1 is the hallmark of chronic myelogenous leukemia (CML) and a subset of de novo acute lymphoblastic leukemia (ALL), but the factors determining disease lineage, and progression of CML to myeloid or lymphoid blast crisis, are inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fba139aa329ce6bab866863e17b5b37
https://doi.org/10.1182/blood.v112.11.1089.1089
https://doi.org/10.1182/blood.v112.11.1089.1089
Autor:
Xiaoping Su, Jeffrey E. Rubnitz, Masami Ishii, Zhongling Cai, Letha A. Phillips, Ina Radtke, Jing Ma, Susana C. Raimondi, James R. Downing, Charles G. Mullighan, Raul C. Ribeiro, Stanley Pounds, James Dalton, Salil Goorha, Ramapriya Ganti, Sheila A. Shurtleff
Publikováno v:
Blood. 110:103-103
To define the complement of genetic lesions in pediatric AML, we performed high resolution genome-wide analysis on bone marrow blasts from 111 cases using Affymetrix 100K and 500K SNP microarrays and genomic resequencing. Cases included t(8;21) (N=20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6448a2058389aeb73bcf7936b48bb4d
https://doi.org/10.1182/blood.v110.11.103.103
https://doi.org/10.1182/blood.v110.11.103.103
Autor:
Radtke, Ina, Mullighan, Charles G., Ishii, Masami, Xiaoping Su, Jinjun Cheng, Jing Ma, Ganti, Ramapriya, Zhongling Cai, Goorha, Salil, Pounds, Stanley B., Xueyuan Cao, Obert, Caroline, Armstrong, Jianling, Jinghui Zhang, Guangchun Song, Ribeiro, Raul C., Rubnitz, Jeffrey E., Raimondi, Susana C., Shurtleff, Sheila A., Downing, James R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/4/2009, Vol. 106 Issue 31, p12944-12949, 6p, 4 Graphs