Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Zhongli, Xu"'
Autor:
Haoran Hu, Xinjun Wang, Site Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O’Hare, Yanshuo Chen, Molin Yue, Lang Zeng, Ziqi Rong, Tianmeng Chen, Timothy Billiar, Ying Ding, Heng Huang, Richard H. Duerr, Wei Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Droplet-based single-cell sequencing techniques rely on the fundamental assumption that each droplet encapsulates a single cell, enabling individual cell omics profiling. However, the inevitable issue of multiplets, where two or more cells a
Externí odkaz:
https://doaj.org/article/63e8e2ce179744b6a2790a44d9e5f6e8
Autor:
Kamakshi Mehta, Marwa Daghsni, Reza Raeisossadati, Zhongli Xu, Emily Davis, Abigail Naidich, Bingjie Wang, Shiyue Tao, Shaohua Pi, Wei Chen, Dennis Kostka, Silvia Liu, Jeffrey M. Gross, Takaaki Kuwajima, Issam Aldiri
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114291- (2024)
Summary: Atoh7 is transiently expressed in retinal progenitor cells (RPCs) and is required for retinal ganglion cell (RGC) differentiation. In humans, a deletion in a distal non-coding regulatory region upstream of ATOH7 is associated with optic nerv
Externí odkaz:
https://doaj.org/article/591410730ffa4292b18f0c57c4a40aa5
Publikováno v:
IEEE Access, Vol 12, Pp 59561-59574 (2024)
Foundation settlement is a common problem in civil engineering. In the case of un-even settlement, it can lead to structural deformation and damage, which seriously affects the safety and reliability of the project. Therefore, the influence of adjust
Externí odkaz:
https://doaj.org/article/9e70f6d6253a49ceb1a92ec4d1fd4f6e
Autor:
Chuanxu Liu, Xinyu Ding, Gaoyang Li, Youping Zhang, Yubao Shao, Linyi Liu, Wenhao Zhang, Yujie Ma, Wenbin Guan, Lifeng Wang, Zhongli Xu, YungTing Chang, Yongqiang Zhang, Biao Jiang, Qianqian Yin, Rong Tao
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107369- (2023)
Summary: Extranodal natural killer/T cell lymphoma, nasal type (ENKTL) is an aggressive lymphoid malignancy with a poor prognosis and lacks standard treatment. Targeted therapies are urgently needed. Here we systematically investigated the druggable
Externí odkaz:
https://doaj.org/article/ccbdfdb490734274a1521bd8d01d1dc2
Autor:
Endry H. T. Lim, Alexander P. J. Vlaar, Lieuwe D. J. Bos, Lonneke A. van Vught, Anita M. Tuip-de Boer, Romein W. G. Dujardin, Maria Habel, Zhongli Xu, Matthijs C. Brouwer, Diederik van de Beek, Sanne de Bruin, the Amsterdam UMC COVID-19 Biobank Investigators
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract We recently reported in the phase 3 PANAMO trial that selectively blocking complement 5a (C5a) with vilobelimab led to improved survival in critically ill COVID-19 patients. C5a is an important contributor to the innate immune system and can
Externí odkaz:
https://doaj.org/article/5d4d30322d4340d189e888acf0f705da
Autor:
Merlijn van Breugel, Cancan Qi, Zhongli Xu, Casper-Emil T. Pedersen, Ilya Petoukhov, Judith M. Vonk, Ulrike Gehring, Marijn Berg, Marnix Bügel, Orestes A. Carpaij, Erick Forno, Andréanne Morin, Anders U. Eliasen, Yale Jiang, Maarten van den Berge, Martijn C. Nawijn, Yang Li, Wei Chen, Louis J. Bont, Klaus Bønnelykke, Juan C. Celedón, Gerard H. Koppelman, Cheng-Jian Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Accurate prediction of the onset of childhood allergy is important to clarify the difference between various respiratory diseases. Here the authors propose that the methylation status of three sites in nasal DNA predicts the onset of childhood allerg
Externí odkaz:
https://doaj.org/article/c100626637b74ab19f631fe608beaa08
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract The recently developed method TEA-seq and similar DOGMA-seq single cell trimodal omics assays provide unprecedented opportunities for understanding cell biology, but independent evaluation is lacking. We explore the utility of DOGMA-seq comp
Externí odkaz:
https://doaj.org/article/2351dac33ab24303aa1d884709507686
Autor:
Zhongli Xu, Xinjun Wang, Li Fan, Fujing Wang, Becky Lin, Jiebiao Wang, Giraldina Trevejo-Nuñez, Wei Chen, Kong Chen
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104900- (2022)
Summary: Understanding lung immunity requires an unbiased profiling of tissue-resident T cells at their precise anatomical locations within the lung, but such information has not been characterized in the immunized mouse model. In this pilot study, u
Externí odkaz:
https://doaj.org/article/02bd31398d99442daa189373e7fdd78d
Autor:
Yale Jiang, Erick Forno, Yueh-Ying Han, Zhongli Xu, Donglei Hu, Nadia Boutaoui, Celeste Eng, Edna Acosta-Pérez, Scott Huntsman, Angel Colón-Semidey, Kevin L. Keys, José R. Rodríguez-Santana, María Alvarez, Maria Pino-Yanes, Glorisa Canino, Wei Chen, Esteban G. Burchard, Juan C. Celedón
Publikováno v:
Epigenetics, Vol 16, Iss 5, Pp 577-585 (2021)
Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two epigenome-wide association studies (EWAS) of asthma, using DNA from white blood cells (WBCs
Externí odkaz:
https://doaj.org/article/cf590e9b7397474d90b1a02e04c96e6c
Autor:
Hongyi Xin, Qiuyu Lian, Yale Jiang, Jiadi Luo, Xinjun Wang, Carla Erb, Zhongli Xu, Xiaoyi Zhang, Elisa Heidrich-O’Hare, Qi Yan, Richard H. Duerr, Kong Chen, Wei Chen
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-35 (2020)
Abstract Identifying and removing multiplets are essential to improving the scalability and the reliability of single cell RNA sequencing (scRNA-seq). Multiplets create artificial cell types in the dataset. We propose a Gaussian mixture model-based m
Externí odkaz:
https://doaj.org/article/966b2483898541929f515a0c96561a8a