Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zhonglei Bao"'
Publikováno v:
Amino Acids. 54:859-875
Human microtubule-associated protein Tau (τ) is abundant in the axons of neurons where it stabilizes microtubule bundles; abnormally hyperphosphorylated τ is a hallmark of Alzheimer's disease (AD) and related tauopathies. The hyperphosphorylation e
Reduction of estrogen levels at the menopause causes the increasing of pro-inflammatory cytokines, the enhancing of bone resorption and the impairing of bone formation, leading to osteoporosis. Previous studies showed that microRNA-34a (miR-34a) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd5a6b871777dba139ecd53ca41342c
https://doi.org/10.21203/rs.3.rs-1476662/v1
https://doi.org/10.21203/rs.3.rs-1476662/v1
Autor:
Zhonglei Bao, Huixue Zhang, Yuze Cao, Xiaoyu Lu, Xiaoming Zhang, Lihua Wang, Shangwei Ning, Liying Cui, Wenqi Tian, Jianjian Wang, Shengnan Sun
Publikováno v:
Neuroscience. 444:106-117
The nucleotide oligomerization domain (NOD)-like receptor (NLR) pyrin domain-containing protein 1 (NLRP1) inflammasome has been shown to contribute to brain injury after ischemic stroke. Our previous study showed that microRNA-9a-5p (miR-9a-5p) ameli
Publikováno v:
Pharmacology. 105:311-319
Introduction: The plaques formed by amyloid-β (Aβ) accumulation and neurofibrillary tangles formed by hyper-phosphorylated tau protein are the 2 major pathologies of Alzheimer’s disease (AD). Recently, autophagy is considered to be a self-degrada
Publikováno v:
Computational Biology and Chemistry. 87:107314
Human Rho-associated coiled-coil forming kinase (ROCK) is a class of essential neurokinases that consists of two structurally conserved isoforms ROCK-I and ROCK-II; they have been revealed to play distinct roles in the pathogenesis of Alzheimer’s d