Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zhongjuan, Xu"'
Publikováno v:
STEMedicine, Vol 3, Iss 1 (2022)
Mesenchymal stem cells (MSCs) have shown great potentials in regenerative medicine for their low immunogenicity, multilineage differentiation potential, and extensive sources. However, the heterogeneity of MSCs limits their clinical application and i
Externí odkaz:
https://doaj.org/article/39465a6951fe45188fb8a94f13896c4b
Autor:
Yanzhen Yu, Xingzhi Liu, Zhe Zhao, Zhongjuan Xu, Yong Qiao, Yuanshuai Zhou, Hong Qiao, Junjie Zhong, Jianwu Dai, Guangli Suo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process. MicroRNA-29 (miR-29) has proved to alleviate the occurrence of PF by downre
Externí odkaz:
https://doaj.org/article/c5eb9fe6fe3241d699a1276f41da673d
Autor:
Zhongjuan Xu, Xingzhi Liu, Yu Wei, Zhe Zhao, Junjun Cao, Yong Qiao, Yanzhen Yu, Junjie Zhong, Guangli Suo
Publikováno v:
STEMedicine, Vol 2, Iss 5 (2020)
Mesenchymal stromal/stem cells (MSCs) have been applied in clinical trials with an increasing number in recent years. MSCs showed their great potentials in regenerative medicine for their extensive sources, multilineage differentiation potential, low
Externí odkaz:
https://doaj.org/article/78afc51d3b3d4752a639348f4a416cf9
Autor:
Xingzhi Liu, Lulu Zhang, Zhongjuan Xu, Xuan Xiong, Yanzhen Yu, Hanfei Wu, Hong Qiao, Junjie Zhong, Zhe Zhao, Jianwu Dai, Guangli Suo
Publikováno v:
Acta biomaterialia. 154
MicroRNA (miRNA)-based therapies have shown great potential in the repair of spinal cord injury (SCI). MicroRNA 21 (miR21) has been proven to have an essential protective effect on SCI. However, there are some challenges for miRNAs application due to
Autor:
Junjie Zhong, Zhe Zhao, Junjun Cao, Bin Wang, Yong Qiao, Zhongjuan Xu, Guangli Suo, Xingzhi Liu
Publikováno v:
Biomedical materials (Bristol, England). 17(1)
The construction of microvascular network is one of the greatest challenges for tissue engineering and cell therapy. Endothelial cells are essential for the construction of network of blood vessels. However, their application meets challenges in clin
Autor:
Junsa Geng, Yan Mei, Guangli Suo, Zhongjuan Xu, Shumang Zhang, Yu Liang, Yanzhen Yu, Tongqian Xiao, Yong Qiao, Bin Wang, Jiali Wei, Qun Dong
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 13:1759-1769
Amyloid plaque is a typical feature of Alzheimer's disease (AD) and is one of the targets for AD therapy. Membrane metalloendopeptidase (MME) and insulin-degrading enzyme (IDE) are two types of proteases that could cleave beta-amyloid (Aβ) peptides
Autor:
Guangli Suo, Yanzhen Yu, Tongqian Xiao, Zhongjuan Xu, Junsa Geng, Qun Dong, Yong Qiao, Hai Zhang, Yu Liang
Publikováno v:
BMB Reports
Epithelial-mesenchymal transition (EMT) is widely-considered to be a modulating factor of anoikis and cancer metastasis. We found that, in MDA-MB-231 cells, TP53I11 (tumor protein P53 inducible protein 11) suppressed EMT and migration in vitro, and i
Autor:
Junjun Cao, Yu Wei, Zhe Zhao, Guangli Suo, Zhongjuan Xu, Xingzhi Liu, Yanzhen Yu, Junjie Zhong, Yong Qiao
Publikováno v:
STEMedicine, Vol 2, Iss 5 (2020)
Mesenchymal stromal/stem cells (MSCs) have been applied in clinical trials with an increasing number in recent years. MSCs showed their great potentials in regenerative medicine for their extensive sources, multilineage differentiation potential, low
Autor:
Guangli Suo, Yuanshuai Zhou, Tongqian Xiao, Junsa Geng, Hong Qiao, Zhongjuan Xu, Yu Liang, Hai Zhang
Publikováno v:
IUBMB Life. 71:183-191
Extracellular matrix (ECM)-independent survival is an essential prerequisite for tumor metastasis, and a hallmark of epithelial cancer stem cells and epithelial-mesenchymal transition (EMT). Here, we found that loss of TP53I11 enhanced, and overexpre
Publikováno v:
Molecular omics. 15(6)
Accumulating evidence has highlighted the important roles of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in Alzheimer's disease (AD). In this study, we constructed an AD-derived lncRNA-associated ceRNA network (LncACeN