Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Zhonghui Lin"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Holliday junction resolution is a crucial process in homologous recombination and DNA double-strand break repair. Complete Holliday junction resolution requires two stepwise incisions across the center of the junction, but the precise mechan
Externí odkaz:
https://doaj.org/article/f872b09a9c874bea94a70e203122154e
Autor:
Xu Zhang, Zixuan Zhou, Lin Dai, Yulin Chao, Zheng Liu, Mingdong Huang, Qianhui Qu, Zhonghui Lin
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Holliday junction (HJ) is a four-way structured DNA intermediate in homologous recombination. In bacteria, the HJ-specific binding protein RuvA and the motor protein RuvB together form the RuvAB complex to catalyze HJ branch migration. Pseudomonas ae
Externí odkaz:
https://doaj.org/article/138bd9e4d6a2419999ff5662d9e715f6
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 109-117 (2022)
Invasive fungal infections including Candidiasis and Aspergillosis are associated with considerable morbidity and mortality in immunocompromised individuals, such as cancer patients. Aurora B is a key mitotic kinase required for the cell division of
Externí odkaz:
https://doaj.org/article/b06e4be3e5fb45878a2e305dba9f046f
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101528- (2022)
Summary: The human MUS81-EME1&2 complexes are structure-selective endonucleases that play important roles in DNA damage repair. Here, we describe a protocol to determine the endonuclease activities of MUS81-EME1&2 complexes toward various DNA structu
Externí odkaz:
https://doaj.org/article/5418d93c1fd64e71a39bd5bc508188a2
Autor:
Ho-Soo Lee, Zhonghui Lin, Sunyoung Chae, Young-Suk Yoo, Byung-Gyu Kim, Youngsoo Lee, Jared L. Johnson, You-Sun Kim, Lewis C. Cantley, Chang-Woo Lee, Hongtao Yu, Hyeseong Cho
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The chromatin remodeler RSF1 is enriched at mitotic centromeres but its function there is poorly understood. Here, the authors show that RSF1 regulates H2A phosphorylation and acetylation at mitotic centromeres and contributes to chromosome stability
Externí odkaz:
https://doaj.org/article/0bf89570019f4e5fb76ec6c3b0d31610
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89469 (2014)
To investigate the impacts of biophysical factors on light response of net ecosystem exchange (NEE), CO2 flux was measured using the eddy covariance technique in a winter wheat field in the North China Plain from 2003 to 2006. A rectangular hyperboli
Externí odkaz:
https://doaj.org/article/2f5b7a28cbbd4d7da44194406c0ee27f
Publikováno v:
Nucleic Acids Research. 51:2485-2495
The cyclic oligoadenylates (cOAs) act as second messengers of the type III CRISPR immunity system through activating the auxiliary nucleases for indiscriminate RNA degradation. The cOA-degrading nucleases (ring nucleases) provide an ‘off-switch’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dfbffe171ecb24bd59b3e4e4a530643
https://doi.org/10.1093/nar/gkad101
https://doi.org/10.1093/nar/gkad101
Autor:
De-Chao Yang, Lin-Feng Wen, Liyang Du, Cheng-Miao Luo, Zi-Yao Lu, Jian-Yong Liu, Zhonghui Lin
Publikováno v:
ACS Applied Materials & Interfaces. 14:40546-40558
Hypoxia-activated prodrugs (HAPs) have drawn increasing attention for improving the antitumor effects while minimizing side effects. However, the heterogeneous distribution of the hypoxic region in tumors severely impedes the curative effect of HAPs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8723ea30c2eb7c2c7dc067b89d4b9650
https://doi.org/10.1021/acsami.2c09071
https://doi.org/10.1021/acsami.2c09071
Publikováno v:
EMBO Journal; 1/16/2024, Vol. 43 Issue 2, p304-315, 12p
Autor:
Siqi Zhang, Xiaohong Chen, Zhonghui Lin, Yaoju Tan, Bin Liang, Yuying Pan, Mingxiang Huang, Biyi Su, Xiaoman Hu, Ye Xu, Qingge Li
Publikováno v:
Journal of Clinical Microbiology.
The quantitative detection of drug-resistance mutations in Mycobacterium tuberculosis (MTB) is critical for determining the drug resistance status of a sample. We developed a drop-off droplet digital PCR (ddPCR) assay targeting all major isoniazid (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63e8429d46026313a91242c643518eb6
https://doi.org/10.1128/jcm.01884-22
https://doi.org/10.1128/jcm.01884-22