Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zhonghui Lai"'
Autor:
Linna Wang, Tan Jiani, Hui Ji, Zhonghui Lai, Meiyu Chen, Yisheng Lai, Jun Zha, Wenyan Long, Ling Liu, Tong Chen
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 45:2632-2642
3-Oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile (ONTD) is a novel synthetic derivative of glycyrrhetinic acid (GA), which has the ability to inhibit the proliferation of human hepatocellular carcinoma (HCC) cells. However, the mechanisms by w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d06641add8345532631004401f9c0c
https://doi.org/10.1016/j.biocel.2013.08.021
https://doi.org/10.1016/j.biocel.2013.08.021
Autor:
Yihua Zhang, Yisheng Lai, Jianhu Xiao, Tan Jiani, Zhonghui Lai, Junxia Pang, Li Ying, Zhangjian Huang, Shengping Zhang, Hui Ji
Publikováno v:
Journal of chemical information and modeling. 54(6)
The NEDD8-activating enzyme (NAE) is an emerging target for cancer therapy, which regulates the degradation and turnover of a variety of cancer-related proteins by activating the cullin-RING E3 ubiquitin ligases. Among a limited number of known NAE i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7356dc27f5cc1ef5a3be28ed37616cb0
https://pubmed.ncbi.nlm.nih.gov/24857708
https://pubmed.ncbi.nlm.nih.gov/24857708
Autor:
Lei Sha, Yisheng Lai, Ran You, Kai Wu, Xing Yu, Hui Ji, Zhonghui Lai, Wenyan Long, Zhangjian Huang, Yihua Zhang
Publikováno v:
Journal of medicinal chemistry. 56(5)
Fifteen novel derivatives of glycyrrhetinic acid (GA) were synthesized and evaluated for anti-inflammatory activities. It was found that the introduction of 1-en-3-one and 9(11),12-diene and 2,20-dinitrile functionalities into the scaffold of GA led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f159cdf77447c36e777515fed63c13f
https://pubmed.ncbi.nlm.nih.gov/23373965
https://pubmed.ncbi.nlm.nih.gov/23373965