Durability of Clinical and Quality-of-Life Outcomes of Closed-Loop Spinal Cord Stimulation for Chronic Back and Leg Pain: A Secondary Analysis of the Evoke Randomized Clinical Trial

Autor: Nagy, Mekhail, Robert M, Levy, Timothy R, Deer, Leonardo, Kapural, Sean, Li, Kasra, Amirdelfan, Corey W, Hunter, Steven M, Rosen, Shrif J, Costandi, Steven M, Falowski, Abram H, Burgher, Jason E, Pope, Christopher A, Gilmore, Farooq A, Qureshi, Peter S, Staats, James, Scowcroft, Tory, McJunkin, Jonathan, Carlson, Christopher K, Kim, Michael I, Yang, Thomas, Stauss, Julie, Pilitsis, Lawrence, Poree, Dan, Brounstein, Samuel, Gilbert, Gerrit E, Gmel, Robert, Gorman, Ian, Gould, Erin, Hanson, Dean M, Karantonis, Abeer, Khurram, Angela, Leitner, Dave, Mugan, Milan, Obradovic, Zhonghua, Ouyang, John, Parker, Peter, Single, Nicole, Soliday

Publikováno v: JAMA Neurol

Chronic pain is debilitating and profoundly affects health-related quality of life. Spinal cord stimulation (SCS) is a well-established therapy for chronic pain; however, SCS has been limited by the inability to directly measure the elicited neural r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::052279d55c73e76a06fbbc7eb12a9ddf
https://pubmed.ncbi.nlm.nih.gov/35156999

Detrusor Pressure Estimation from Single-Channel Urodynamics

Autor: Farhath, Zareen, Zhonghua, Ouyang, Steve J A, Majerus, Tim M, Bruns, Margot S, Damaser, Robert, Karam

Publikováno v: 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

Urodynamics is the current gold-standard for diagnosing lower urinary tract dysfunction, but uses non-physiologically fast, retrograde cystometric filling to obtain a brief snapshot of bladder function. Ambulatory urodynamics allows physicians to eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be62c01723cbee7d1345b631ffa8c15d
https://doi.org/10.1109/embc48229.2022.9871663

Sharpened and Mechanically Durable Carbon Fiber Electrode Arrays for Neural Recording

Autor: Ahmad A. Jiman, Joshua E. Woods, Elizabeth C. Bottorff, Julianna M. Richie, Paras R. Patel, John P. Seymour, Tim M. Bruns, Elissa J. Welle, Cynthia A. Chestek, Zhonghua Ouyang

Publikováno v: IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

Bioelectric medicine treatments target disorders of the nervous system unresponsive to pharmacological methods. While current stimulation paradigms effectively treat many disorders, the underlying mechanisms are relatively unknown, and current neuros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11120c3d61d9b8948c0168a97e181863
https://doi.org/10.1109/tnsre.2021.3082056

Real-Time Bladder Pressure Estimation for Closed-Loop Control in a Detrusor Overactivity Model

Autor: Zachariah J. Sperry, Nikolas D. Barrera, Zhonghua Ouyang, Tim M. Bruns

Publikováno v: IEEE Trans Neural Syst Rehabil Eng

Overactive bladder (OAB) patients suffer from a frequent urge to urinate, which can lead to a poor quality of life. Current neurostimulation therapy uses open-loop electrical stimulation to alleviate symptoms. Continuous stimulation facilitates habit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac6dc276b203bd68228682f82794e19
https://doi.org/10.1109/tnsre.2019.2912374

Bladder pressure encoding by near-independent fibre subpopulations – implications for decoding

Autor: Nick S. Jones, Tim M. Bruns, Zhonghua Ouyang, Carl H Lubba, Simon R. Schultz

ObjectiveWe aim at characterising the encoding of bladder pressure (intravesical pressure) by a population of sensory fibres. This research is motivated by the possibility to restore bladder function in elderly patients or after spinal cord injury us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27e45604e5afaf49102201b000cf346