Zobrazeno 1 - 10
of 1 289
pro vyhledávání: '"Zhonggao"'
Autor:
Bowen Zeng, Lina Pian, Yanhong Liu, Shuangqing Wang, Nuoya Wang, Chao Liu, Hao Wu, Hongshuang Wan, Liqing Chen, Wei Huang, Zhonggao Gao, Xuezhe Yin, Mingji Jin
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Breast cancer therapy has significantly advanced by targeting the programmed cell death-ligand 1/programmed cell death-1 (PD-L1/PD-1) pathway. BMS-202 (a smallmolecule PD-L1 inhibitor) induces PD-L1 dimerization to block PD-1/PD-L1 interacti
Externí odkaz:
https://doaj.org/article/51f62b1377604f8bb41e12e6d76353bc
Autor:
Manqing Tang, Zhijie Zhang, Ping Wang, Feng Zhao, Lin Miao, Yuming Wang, Yingpeng Li, Yunfei Li, Zhonggao Gao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3457-3475 (2024)
Tumor metastasis, the apex of cancer progression, poses a formidable challenge in therapeutic endeavors. Circulating tumor cells (CTCs), resilient entities originating from primary tumors or their metastases, significantly contribute to this process
Externí odkaz:
https://doaj.org/article/51e28a2a85c744a2877eb44cbb71628e
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundThe relationship between selenium and renal function has always attracted widespread attention. Increased selenium level has been found to cause impaired renal function in our previous study, but the mechanism is not clear. In this study, w
Externí odkaz:
https://doaj.org/article/316120c545294edcb497cff30effb985
Autor:
Shaojie Fu, Jingda Huang, Zhenbang Feng, Haitao Wang, Hongzhao Xu, Meiyan Wu, Fuzhe Ma, Zhonggao Xu
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Background There is currently no research on the correlation between novel inflammatory indexes systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and the risk of anemia in chronic kidn
Externí odkaz:
https://doaj.org/article/8d16c67c87e14fb1abac8fb2852c5e50
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The pathophysiological mechanisms involved in fibrotic interstitial lung diseases (FILDs) are akin to those observed in idiopathic pulmonary fibrosis (IPF), implying the potential for shared therapeutic approaches. Pirfenidone exhibits antifibrotic a
Externí odkaz:
https://doaj.org/article/0cdb5f8827df4490a657d1eb680808c8
Autor:
Shaojie Fu, Meiyan Wu, Yanli Cheng, Yan Guan, Jinyu Yu, Xueyao Wang, Sensen Su, Hao Wu, Fuzhe Ma, Yan Zou, Shan Wu, Hongzhao Xu, Zhonggao Xu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIgA nephropathy (IgAN), a prevalent form of glomerulonephritis globally, exhibits complex pathogenesis. Cathepsins, cysteine proteases within lysosomes, are implicated in various physiological and pathological processes, including renal c
Externí odkaz:
https://doaj.org/article/16ec20b1febc459e821c6a01c6afa459
Publikováno v:
Heritage Science, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Heritage landscapes provide a cost-effective solution for mitigating noise and creating adaptable open spaces in urban ecological construction and planning. In this study, we examined 27 distinct landscapes in a city in northern China to ass
Externí odkaz:
https://doaj.org/article/ae4fc7f6d9984b26a3c6c3940470fdef
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
RationaleMonoclonal gammopathy of renal significance (MGRS) represents a group of disorders caused by monoclonal immunoglobulin (M protein) secreted by B cells or plasma cells. Proliferative glomerulonephritis with monoclonal immunoglobulin depositio
Externí odkaz:
https://doaj.org/article/8427fc317b6a4cf080426c458828ec80
Publikováno v:
Shipin gongye ke-ji, Vol 44, Iss 22, Pp 12-18 (2023)
Objective: To investigate the synergistic antioxidant effects of different ratios of EGCG (epigallocatechin gallate) and isorhamnetin combinations, and provide a theoretical basis for the development of food borne flavonoid functional foods. Methods:
Externí odkaz:
https://doaj.org/article/0786c1a8a486466bbfa56b60816ccf38
Publikováno v:
Shipin gongye ke-ji, Vol 44, Iss 19, Pp 374-381 (2023)
Objective: In order to find the effects of nitric oxide on the storage qualities and antioxidant activities of postharvest peach fruits. Methods: The flesh firmness, contents of cell wall pectins, soluble sugars, titratable acids, total phenols and f
Externí odkaz:
https://doaj.org/article/193630d365db4f149796a23da97c8ab6