Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Zhongfang Weng"'
Autor:
Zhongfang Weng, Cao, Catherine, Stepicheva, Nadezda A., Fenghua Chen, Foley, Lesley M., Cao, Sarah, Bhuiyan, Mohammad Iqbal H., Qingde Wang, Yuan Wang, Hitchens, T. Kevin, Sun, Dandan, Guodong Cao
Publikováno v:
Journal of Neuroscience; 11/1/2023, Vol. 43 Issue 44, p7351-7360, 10p
Autor:
Fenghua Chen, Steven H. Graham, Lihong Han, Zhongfang Weng, Guodong Cao, Qinghai Xia, Catherine Cao, Jian Xiao, Rehana K. Leak
Publikováno v:
Transl Stroke Res
Our previous study indicated that nicotinamide phosphoribosyltransferase (NAMPT) is released from cells and might be an important extracellular neuroprotective factor in brain ischemia. Here we tested whether NAMPT protects against ischemic brain inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35e96a29d9e15eea78709207b2d0779
https://europepmc.org/articles/PMC6713626/
https://europepmc.org/articles/PMC6713626/
Autor:
Yanqin Gao, Yejie Shi, Feng Zhang, Gregg E. Homanics, Michael V. L. Bennett, Jun Chen, Hongjian Pu, Rehana K. Leak, Sulaiman H Hassan, Guodong Cao, Xiaoming Hu, Zhongfang Weng, Carolyn Ferguson, R. Anne Stetler, Lili Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(25)
A major hallmark of oxidative DNA damage after stroke is the induction of apurinic/apyrimidinic (AP) sites and strand breaks. To mitigate cell loss after oxidative DNA damage, ischemic cells rapidly engage the base excision-repair proteins, such as t
Publikováno v:
Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis
Autor:
Peter S. Vosler, Yanqin Gao, Lili Zhang, R. Anne Stetler, Jun Chen, Steven H. Graham, Feng Zhang, Guodong Cao, Zhongfang Weng, Armando P. Signore, Suping Wang
Publikováno v:
The Journal of Neuroscience. 28:13038-13055
Heat shock protein 27 (Hsp27), a recently discovered member of the heat shock protein family, is markedly induced in the brain after cerebral ischemia and other injury states. In non-neuronal systems, Hsp27 has potent cell death-suppressing functions
Publikováno v:
Journal of Neurochemistry. 106:1977-1990
Leptin is well known as a hormone important in the central control of appetitive behaviors via receptor-mediated actions in the hypothalamus, where leptin adjusts food intake to maintain homeostasis with the body’s energy stores. Recent evidence ha
Autor:
Teresa G. Hastings, Jun Chen, Yong J. Lee, Armando P. Signore, Qinghua Liang, Zhongfang Weng, Amber D. Van Laar
Publikováno v:
Journal of Neurochemistry. 96:428-443
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the death of midbrain dopaminergic neurons. In the present study, erythropoietin, a trophic factor that has both hematopoietic and neural protective characteristics, was invest
Autor:
Jun Chen, Hassan H. Sulaiman, Rehana K. Leak, Guodong Cao, Peiying Li, Guo-Hua Wang, R. Anne Stetler, Feng Zhang, Yejie Shi, Yanqin Gao, Zhongfang Weng
Publikováno v:
Antioxidantsredox signaling. 22(2)
Aims: Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme that participates in base-excision repair of oxidative DNA damage and in the redox activation of transcription factors. We tested the hypothesis that APE1 upregulation prot
Autor:
Peter S. Vosler, Xiecheng Michelle Ma, Bryan N. Brown, Feng Zhang, Ling Zhang, Jun Chen, Hongqu Yan, C. Edward Dixon, Zhongfang Weng, Stephen F. Badylak, Xinyan Tracy Cui
Traumatic brain injury (TBI) is a major public health problem with no effective clinical treatment. Use of bioactive scaffold materials has been shown to be a promising strategy for tissue regeneration and repair in a number of injury models. Of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4596ca03c21f8ed6914cabd07ce838
https://europepmc.org/articles/PMC3726021/
https://europepmc.org/articles/PMC3726021/
Autor:
Jie, Chen, Anthony, Liou, Lili, Zhang, Zhongfang, Weng, Yanqin, Gao, Guodong, Cao, Michael J, Zigmond, Jun, Chen
Publikováno v:
Frontiers in bioscience (Elite edition). 4(7)
The enhanced neurotoxicity of the Parkinson’s disease-associated LRRK2 mutant, G2019S, than its wild-type counter-part has recently been reported. Overexpression of LRRK2 (G2019S) in cultured neural cells results in caspase-3-dependent apoptosis vi