Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zhongen Wu"'
Autor:
Fenglian He, Zhongen Wu, Chenglong Liu, Yuanyuan Zhu, Yan Zhou, Enming Tian, Rina Rosin-Arbesfeld, Dehua Yang, Ming-Wei Wang, Di Zhu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Conventional type 1 dendritic cells (cDC1) are the essential antigen-presenting DC subset in antitumor immunity. Suppressing B-cell lymphoma 9 and B-cell lymphoma 9-like (BCL9/BCL9L) inhibits tumor growth and boosts immune responses against
Externí odkaz:
https://doaj.org/article/72e1fa687b1e4cd49952ca21d83b7d45
Autor:
Xiaoshuang Wang, Yan Zhou, Zhongen Wu, Cao Xie, Weiqi Xu, Qingtong Zhou, Dehua Yang, Di Zhu, Ming-Wei Wang, Lu Wang
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108896- (2024)
Summary: Liver metastasis (LM) is the primary cause of cancer-related mortality in late-stage breast cancer (BC) patients. Here we report an in-depth analysis of the transcriptional landscape of LM of 11 patients with secondary hepatic carcinoma at s
Externí odkaz:
https://doaj.org/article/bc577b3297f74819abecd8602dd4624c
Autor:
Li Xia, Enming Tian, Mingcheng Yu, Chenglong Liu, Lian Shen, Yafei Huang, Zhongen Wu, Jinlong Tian, Ker Yu, Yonghui Wang, Qiong Xie, Di Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-23 (2022)
Abstract Background The overall response rate to checkpoint blockade remains unsatisfactory, partially due to the immune-suppressive tumor microenvironment. A retinoic acid-related orphan receptor γt (RORγt) agonist (LYC-55716) is currently used in
Externí odkaz:
https://doaj.org/article/75b90835d1124728851ce9db56e3fc3d
Publikováno v:
Medicine in Drug Discovery, Vol 16, Iss , Pp 100144- (2022)
Colorectal cancer (CRC) is a common cancer in the world and also has a high death rate. It is reported that vaccination is a great strategy for CRC. CRC vaccines are based on CRC tumor antigens, including tumor-associated antigens like CEA, MUC-1, CT
Externí odkaz:
https://doaj.org/article/a1b073de66704967b3d97dc0e2368c1e
Autor:
Mei Feng, Zhongen Wu, Yan Zhou, Zhuang Wei, Enming Tian, Shenglin Mei, Yuanyuan Zhu, Chenglong Liu, Fenglian He, Huiyu Li, Cao Xie, Joy Jin, Jibin Dong, Dehua Yang, Ker Yu, Junbin Qian, Diether Lambrechts, Ming-Wei Wang, Di Zhu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract To date, the overall response rate of PD-1 blockade remains unsatisfactory, partially due to limited understanding of tumor immune microenvironment (TIME). B-cell lymphoma 9 (BCL9), a key transcription co-activator of the Wnt pathway, is hig
Externí odkaz:
https://doaj.org/article/d74d6c50bfa84e0791095b5a904f6f86
Publikováno v:
IEEE Photonics Journal, Vol 13, Iss 6, Pp 1-6 (2021)
Holography can produce the most real three-dimensional (3D) image, and is considered as the ultimate 3D display technology. However, compared with other display technologies, it has not been practically available in video display so far due to low re
Externí odkaz:
https://doaj.org/article/732167aca9414ee89e91783cf81ed520
Autor:
Weizhen Li, Yang Zhou, Zhongen Wu, Yaoping Shi, Enming Tian, Yingqi Zhu, Tao Wang, Wei Dou, Xiangjing Meng, Ming Chen, Bo Zhai, Di Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Colorectal cancer (CRC) patients are still lacking viable treatments. Chimeric antigen receptor (CAR) T cells have shown promise in hematologic malignancies, but their efficacy in solid tumors has been limited due to the immunosuppressive tumor micro
Externí odkaz:
https://doaj.org/article/e8eaa924bfc24ff78be42a2d416dbc50
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Tumor-associated macrophages (TAMs) are an indispensable part of the tumor microenvironment (TME), and they likely play a negative rather than positive role in cancer treatment. However, the cellular landscape and transcriptional profile regulation o
Externí odkaz:
https://doaj.org/article/b59597df87e7481ca9f84b8f2d1c09d8
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Tumor endothelial cells are an important part of the tumor microenvironment, and angiogenesis inhibitory therapy has shown potential in tumor treatment. However, which subtypes of tumor endothelial cells are distributed in tumors, what are the differ
Externí odkaz:
https://doaj.org/article/720974947d6a4217bbac9d145c100508
Publikováno v:
IEEE Photonics Journal, Vol 13, Iss 6, Pp 1-6 (2021)
Holography can produce the most real three-dimensional (3D) image, and is considered as the ultimate 3D display technology. However, compared with other display technologies, it has not been practically available in video display so far due to low re