Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Zhongde Ye"'
Autor:
Yue Wang, Jie Xue, Umesh Muchhal, Keyu Li, Angus Sinclair, Poonam Yakkundi, Rodnie Rosete, Bruce Keyt, Liqin Liu, Deepal Pandya, Vidhya Bai Krishnoji Rao, Elizabeth Perez, Paul Hinton, Gene Li, Kristene Mai, Nardeen Hanna, Zhongde Ye, Jinqiu Wang, Tina Mao, Palak Chudasama, Sachi Rahman, Zee Malik, Krzysztof Bzymek
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/48b4c1c1bc81453ba906e5b5b2b62cf8
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-9 (2021)
Abstract MicroRNAs (miRNAs) are regulatory noncoding RNAs important for many aspects of cellular processes including cell differentiation and proliferation. Functions of numerous miRNAs have been identified in T cells, with miR-181a regulating T cell
Externí odkaz:
https://doaj.org/article/dd787b5dcc1347109dff3106b848ff2f
Autor:
Zhongde Ye, Yi Shen, Ke Jin, Jingtao Qiu, Bin Hu, Rohit R. Jadhav, Khushboo Sheth, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
ORAI3 is part of pore forming calcium channels involved in T cell activation. Here the authors show that there is increased expression of ORAI3 in T cells from patients with rheumatoid arthritis and that the transcription factor IKAROS negatively reg
Externí odkaz:
https://doaj.org/article/1194013638654e75b64350cd53e610e5
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract MicroRNAs play an important role in the regulation of T cell development, activation, and differentiation. One of the most abundant microRNAs in lymphocytes is miR-181a, which controls T cell receptor (TCR) activation thresholds in thymic se
Externí odkaz:
https://doaj.org/article/08e6f57628f742cbbf6c188b84d4f6a7
Autor:
Bin Hu, Rohit R. Jadhav, Claire E. Gustafson, Sabine Le Saux, Zhongde Ye, Xuanying Li, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1ffebb6d2fb24fafa2db95ebc9619d17
Autor:
Rohit R. Jadhav, Bin Hu, Zhongde Ye, Khushboo Sheth, Xuanying Li, William J. Greenleaf, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103825- (2022)
Summary: Background: Rheumatoid arthritis (RA) is an inflammatory disease that manifests as a preclinical stage of systemic autoimmunity followed by chronic progressive synovitis. Disease-associated genetic SNP variants predominantly map to non-codin
Externí odkaz:
https://doaj.org/article/9ef57889fd484af4ab84ef130e9839ea
Autor:
Bin Hu, Rohit R. Jadhav, Claire E. Gustafson, Sabine Le Saux, Zhongde Ye, Xuanying Li, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Healthy immune aging is in part determined by how well the sizes of naïve T cell compartments are being maintained with advancing age. Throughout adult life, replenishment largely derives from homeostatic proliferation of existing naïve and memory
Externí odkaz:
https://doaj.org/article/76228a1ac19d48b78d55a957577b26da
Autor:
Zhongde Ye, Guangjin Li, Chulwoo Kim, Bin Hu, Rohit R. Jadhav, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
MicroRNA miR-181a has been implicated in the regulation of T cell activation and development. Here the authors show that miR-181a is regulated by a transcription factor, YY1, with reduced YY1 expression linked to reduced miR-181a in old individuals,
Externí odkaz:
https://doaj.org/article/a7b0dbcfdb714b22a13d1c459e41ea47
Autor:
Fengqin Fang, Mingcan Yu, Mary M. Cavanagh, Jessica Hutter Saunders, Qian Qi, Zhongde Ye, Sabine Le Saux, William Sultan, Emerson Turgano, Cornelia L. Dekker, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1218-1231 (2016)
Summary: In an immune response, CD4+ T cells expand into effector T cells and then contract to survive as long-lived memory cells. To identify age-associated defects in memory cell formation, we profiled activated CD4+ T cells and found an increased
Externí odkaz:
https://doaj.org/article/c6d5eafc2bd946109c7b4953a251f2c2
Publikováno v:
Frontiers Research Topics ISBN: 9782832513224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9940cadbfdb7e64d2e72e736394976