Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Zhongcheng Cao"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
To discover novel multifunctional agents for the treatment of Parkinson’s disease, a series of 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives was designed, synthesized and evaluated. The results revealed that representative compoun
Externí odkaz:
https://doaj.org/article/6865a0b7fce344078fd4ef62dabbc9db
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 69-85 (2022)
A novel series of chalcone-Vitamin E-donepezil hybrids was designed and developed based on multitarget-directed ligands (MTDLs) strategy for treating Alzheimer’s disease (AD). The biological results revealed that compound 17f showed good AChE inhib
Externí odkaz:
https://doaj.org/article/3e3089f1b6be45ab99641b37a3981463
Autor:
Zhongcheng Cao, Teng Wang
Publikováno v:
Frontiers in Environmental Science, Vol 10 (2022)
Loess deposits are widely distributed in western and central China. Because loess is wet-collapsible, loess mass is prone to failure after water infiltration. Heifangtai, composed of two adjacent typical loess platforms located in the Loess Plateau b
Externí odkaz:
https://doaj.org/article/4f816e5242f74ce2aa9463a4320d6e57
Publikováno v:
ChemMedChem. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c082a6f91a56146cf3390e6312463e3
https://doi.org/10.1002/cmdc.202200629
https://doi.org/10.1002/cmdc.202200629
Publikováno v:
European Journal of Medicinal Chemistry. 249:115142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8814c7747b3f336da53a8d5ddd9cf939
https://doi.org/10.1016/j.ejmech.2023.115142
https://doi.org/10.1016/j.ejmech.2023.115142
Publikováno v:
Earthquake Science. 33:246-255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c91d8de1b572e0cbd82c7b2facf287fc
https://doi.org/10.29382/eqs-2020-0246-01
https://doi.org/10.29382/eqs-2020-0246-01
Autor:
Zhang Xiaoyu, Heng Zhang, Qing Song, Zhongcheng Cao, Yang Ziyi, Yong Deng, Tian Chaoquan, Yan Li
Publikováno v:
Bioorganic Chemistry. 87:395-408
A series of chalcone Mannich base derivatives were designed, synthesized and evaluated as multifunctional agents for the treatment of Alzheimer’s disease based on the multi-target directed ligands design strategy. In vitro assays demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13bd73e3abc93f266bb62a48f5f89786
https://doi.org/10.1016/j.bioorg.2019.03.043
https://doi.org/10.1016/j.bioorg.2019.03.043
Autor:
Zhongcheng Cao, Qing Song, Xiaoming Qiang, Hongyan Liu, Yang Ziyi, Yong Deng, Zhenghuai Tan, Tian Chaoquan, Yan Li
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:6115-6127
A series of 2,5-dihydroxyterephthalamide derivatives were designed, synthesized and evaluated as multifunctional agents for the treatment of Alzheimer’s disease. In vitro assays demonstrated that most of the derivatives exhibited good multifunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b234e20649ca53cf31610aac81217eae
https://doi.org/10.1016/j.bmc.2018.11.015
https://doi.org/10.1016/j.bmc.2018.11.015
Publikováno v:
Bioorganicmedicinal chemistry. 35
To discover novel multifunctional agents for the treatment of Alzheimer’s disease, a series of 3-benzylidene/benzylphthalide Mannich base derivatives were designed, synthesized and evaluated. The biological screening results indicated that most of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1719950fee1efdc64ed2dc31a26874
https://pubmed.ncbi.nlm.nih.gov/33640707
https://pubmed.ncbi.nlm.nih.gov/33640707
Autor:
Yichun Shi, Qing Song, Xiuxiu Liu, Yong Deng, Guangjun Yu, Xu Rui, Zhuoling Liu, Chanyuan Ye, Zhongcheng Cao
Publikováno v:
Bioorganic chemistry. 111
A series of 4-aminoalkyl-1(2H)-phthalazinone derivatives was designed and synthesized as potential multifunctional agents for Alzheimer's disease (AD) treatment. In vitro biological assay results demonstrated that most synthesized compounds exhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c67bdfacc724e51e3ab46ded9e7c6c8
https://pubmed.ncbi.nlm.nih.gov/33887586
https://pubmed.ncbi.nlm.nih.gov/33887586