Zobrazeno 1 - 10
of 143
pro vyhledávání: '"ZhongLi Cai"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-47 (2024)
Abstract Background Radiation nanomedicines are nanoparticles labeled with radionuclides that emit α- or β-particles or Auger electrons for cancer treatment. We describe here our 15 years scientific journey studying locally-administered radiation n
Externí odkaz:
https://doaj.org/article/f9e358b23e8e4dacb115690df9203267
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109750- (2024)
Summary: HER2 heterogeneity is a challenge for molecular imaging or treating HER2-positive breast cancer (BC). EGFR is coexpressed in some tumors exhibiting HER2 heterogeneity. Bispecific radioimmunoconjugates (bsRICs) that bind HER2 and EGFR were co
Externí odkaz:
https://doaj.org/article/1f6222674072471191626dfa25582a11
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-22 (2023)
Abstract Background Trastuzumab (Herceptin) has improved the outcome for patients with HER2-positive breast cancer (BC) but brain metastases (BM) remain a challenge due to poor uptake of trastuzumab into the brain. Radioimmunotherapy (RIT) with trast
Externí odkaz:
https://doaj.org/article/f1a9c05aa2e34242a469a3232534ab37
Autor:
Anthony Ku, Misaki Kondo, Zhongli Cai, Jalna Meens, Min Rong Li, Laurie Ailles, Raymond M. Reilly
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-22 (2021)
Abstract Background Epidermal growth factor receptors (EGFR) are overexpressed on many head and neck squamous cell carcinoma (HNSCC). Radioimmunotherapy (RIT) with F(ab')2 of the anti-EGFR monoclonal antibody panitumumab labeled with the β-particle
Externí odkaz:
https://doaj.org/article/87d0c0930f2949c9a68e8c753d2b9c38
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-19 (2020)
Abstract Background Epidermal growth factor receptors (EGFR) are overexpressed on > 90% of pancreatic cancers (PnCa) and represent an attractive target for the development of novel therapies, including radioimmunotherapy (RIT). Our aim was to study R
Externí odkaz:
https://doaj.org/article/945e2356dc0843e299a516643d1e44a3
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-36 (2019)
Abstract Background Auger electrons (AEs) are very low energy electrons that are emitted by radionuclides that decay by electron capture (e.g. 111In, 67Ga, 99mTc, 195mPt, 125I and 123I). This energy is deposited over nanometre-micrometre distances, r
Externí odkaz:
https://doaj.org/article/f4fb0e0c49b4487d9797184ae39712ea
Autor:
Constantine J. Georgiou, Zhongli Cai, Noor Alsaden, Hyungjun Cho, Minou Behboudi, Mitchell A. Winnik, James T. Rutka, Raymond M. Reilly
Publikováno v:
Molecular Pharmaceutics. 20:582-592
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f16a44918bba754b5c306fcf0da3a3e9
https://doi.org/10.1021/acs.molpharmaceut.2c00815
https://doi.org/10.1021/acs.molpharmaceut.2c00815
Autor:
Zhongli Cai, Rella Liu, Conrad Chan, Yijie Lu, Mitchell A. Winnik, David W. Cescon, Raymond M. Reilly
Publikováno v:
Molecular Pharmaceutics. 19:4199-4211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26d4e2a84b46c037c9da32e50a6e2f5
https://doi.org/10.1021/acs.molpharmaceut.2c00572
https://doi.org/10.1021/acs.molpharmaceut.2c00572
Publikováno v:
Molecular Pharmaceutics. 19:3652-3663
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::867284b0890b3fb74b430da7aa835997
https://doi.org/10.1021/acs.molpharmaceut.2c00457
https://doi.org/10.1021/acs.molpharmaceut.2c00457
Autor:
Min Rong Li, Jalna Meens, Anthony Ku, Zhongli Cai, Laurie Ailles, Misaki Kondo, Raymond M. Reilly
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-22 (2021)
Background Epidermal growth factor receptors (EGFR) are overexpressed on many head and neck squamous cell carcinoma (HNSCC). Radioimmunotherapy (RIT) with F(ab')2 of the anti-EGFR monoclonal antibody panitumumab labeled with the β-particle emitter,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204c604ebe66b31f14ef694453194435
https://doaj.org/article/87d0c0930f2949c9a68e8c753d2b9c38
https://doaj.org/article/87d0c0930f2949c9a68e8c753d2b9c38