Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zhong-hai Yu"'
Autor:
Jun Xiang, Feng Yang, Wen Zhu, Min Cai, Xiang-Ting Li, Jing-Si Zhang, Zhong-Hai Yu, Wen Zhang, Ding-Fang Cai
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The pathogenesis of Alzheimer’s disease (AD) involves multiple cell types including endothelial cells, glia, and neurons. It suggests that therapy against single target in single cell type may not be sufficient to treat AD and therapies wi
Externí odkaz:
https://doaj.org/article/76080194c0d046b4b2df9acc6bfc0146
Autor:
Jun Xiang, Wen Zhang, Xiao-Fang Cai, Min Cai, Zhong-Hai Yu, Feng Yang, Wen Zhu, Xiang-Ting Li, Ting Wu, Jing-Si Zhang, Ding-Fang Cai
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 302-312 (2019)
β-amyloid (Aβ) plays an essential role in the pathogenesis of Alzheimer’s disease (AD). Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is indispensable for Aβ production, and knockout of BACE1 has no overt phenotypes in mouse. Thu
Externí odkaz:
https://doaj.org/article/ddf2458ef5e0427794009065bf25b8a6
Autor:
Qiang Zhang, Zhong-Hai Yu, Xiangting Li, Yaming Li, Yuanjin Chan, Zhongkuan Lyu, Dingfang Cai, Jun Xiang, Qiyue Li, Kaili Liu, Bing Wang
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2021 (2021)
Neural Plasticity, Vol 2021 (2021)
Neuroinflammation-related amyloid-beta peptide (Aβ) accumulation after cerebral ischemia/reperfusion (I/R) accounts for cerebral I/R injuries and poststroke dementia. Recently, pyroptosis, a proinflammatory cell death, has been identified as a cruci
Autor:
Jing-Si Zhang, Xiangting Li, Min Cai, Xiaofang Cai, Wen Zhang, Jun Xiang, Dingfang Cai, Wen Zhu, Zhong-Hai Yu, Feng Yang
Publikováno v:
Biochemical and Biophysical Research Communications. 526:553-559
Background Inflammasome activation and followed by the release of proinflammatory cytokines play a pivotal role in the development and progression of depression. However, the involvement of gasdermin D (GSDMD)-mediated pyroptosis in inflammasome-asso
Autor:
Wen Zhang, Dingfang Cai, Min Cai, Xiangting Li, Jun Xiang, Zhong-Hai Yu, Feng Yang, Wen Zhu, Jing-Si Zhang
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
The pathogenesis of Alzheimer’s disease (AD) involves multiple cell types including endothelial cells, glia, and neurons. It suggests that therapy against single target in single cell type may not be sufficient to treat AD and therapies with protec
Autor:
Wen Zhu, Jun Xiang, Zhong-Hai Yu, Jing-Si Zhang, Wen Zhang, Feng Yang, Min Cai, Xiangting Li, Dingfang Cai
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Stroke is a leading reason of death and long-term disability, and most studies mainly focus on efforts to protect neurons. However, failed clinical trials suggest that therapies against single target in neurons may not be sufficient and the involveme
Autor:
Jun Xiang, Wen Zhu, Feng Yang, Zhong-Hai Yu, Min Cai, Xiang-Ting Li, Jing-Si Zhang, Wen Zhang, Ding-Fang Cai
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-1 (2020)
Translational Psychiatry, Vol 10, Iss 1, Pp 1-1 (2020)
Stroke is a leading reason of death and long-term disability, and most studies mainly focus on efforts to protect neurons. However, failed clinical trials suggest that therapies against single target in neurons may not be sufficient and the involveme
Publikováno v:
Applied Mechanics and Materials. :156-161
As a new tool and new approach in the scientific development of surveying and mapping service, the mission of geographic national condition monitoring is to provide objective, fair and accurate thematic information for integrated decision-making at a
Publikováno v:
Applied Mechanics and Materials. :301-305
The rise of the Flexible Manufacturing System (FMS) and the Computer Integrated Manufacturing System (CIMS) put forward a more urgent need for the practical fixture design software. 3D Visual Basic-based standard parts library is proposed in this pap
Publikováno v:
Journal of Chinese Integrative Medicine. 10:628-634
BACKGROUND Mild cognitive impairment is a transitional stage between normal aging and dementia. It is important in terms of recognizing memory loss in older people as well as identifying a group of individuals at high risk of developing dementia and