Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zhong-guo Zhang"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroudOxygen metabolism is an important factor affecting the development of tumors, but its roles and clinical value in Colorectal cancer are not clear. We developed an oxygen metabolism (OM) based prognostic risk model for colorectal cancer and e
Externí odkaz:
https://doaj.org/article/e4a9e3649ac34e07918235807e9db7ea
Autor:
Zhong‐guo Zhang, Fei Ma, Shuang Zhao, Xiaoyu Yang, Fang Liu, Chenghai Xue, Liren Liu, Jin Gu, Haozhe Piao
Publikováno v:
Cancer Medicine, Vol 8, Iss 10, Pp 4732-4742 (2019)
Abstract Background The quantity of metastases lesions is an important reference when it comes to making a more informed treatment decision for patients with colorectal cancer liver metastases. However, the molecular alterations in patients with diff
Externí odkaz:
https://doaj.org/article/b33be7c69f554cc291104e8c2d841b75
Autor:
Jin Gu, Haozhe Piao, Fang Liu, Fei Ma, Xiaoyu Yang, Chenghai Xue, Shuang Zhao, Liren Liu, Zhong‐guo Zhang
Publikováno v:
Cancer Medicine, Vol 8, Iss 10, Pp 4732-4742 (2019)
Cancer Medicine
Cancer Medicine
Background The quantity of metastases lesions is an important reference when it comes to making a more informed treatment decision for patients with colorectal cancer liver metastases. However, the molecular alterations in patients with different num
Publikováno v:
Experimental Cell Research. 379:182-190
Lysine demethylase 5B (KDM5B) is up-regulated in many cancers, including breast cancer. However, the underlying metabolic mechanisms of KDM5B on breast cancer progression are poorly understood. Here, we showed that KDM5B expression positively correla
Autor:
Xiao-Ying Yu, Hu Li, Dan-Ning Xiong, Hong-Sheng Zhang, Yinghui Huang, Yu-Ting Shi, Hong-Liang Sun, Zhen Zhou, Guang-Yuan Du, Zhong-Guo Zhang
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 95:85-92
High aerobic glycolysis not only provides energy to breast cancer cells, but also supports their anabolic growth. The redox sensitive transcription factor NRF2 is over-expressed in multiple cancers, including breast cancer. It is unclear whether NRF2
Autor:
Hong-Sheng Zhang, Guang-Yuan Du, Yinghui Huang, Zhong-Guo Zhang, Zhen Zhou, Hu Li, Xiao-Ying Yu
Publikováno v:
Archives of Biochemistry and Biophysics. :17-23
Considerable evidence has shown that autophagy has an important role in HIV-1 infection. However, it is still unknown whether metabolism-regulated autophagy pathway is involved in Tat-mediated HIV-1 transactivation. This study demonstrated that treat
Publikováno v:
Oncotarget
Circulating tumor cells (CTCs) are used for metastasis surveillance in cancer patients, but low detection rates limit their use in colorectal cancer (CRC). We investigated the distribution of CTCs in peripheral and portal blood of CRC patients, and a
Autor:
Yinghui Huang, Zhen Zhou, Xiao-Ying Yu, Guang-Yuan Du, Hong-Sheng Zhang, Hu Li, Yang Liu, Zhong-Guo Zhang
Publikováno v:
Journal of Cellular Physiology. 233:1359-1369
Epigenetic modifications such as histone modifications and cytosine hydroxymethylation are linked to tumorigenesis. Loss of 5-hydroxymethylcytosine (5hmC) by ten-eleven translocation 1 (TET1) down-regulation facilitates tumor initiation and developme
Publikováno v:
Clinical Trials in Degenerative Diseases, Vol 2, Iss 3, Pp 53-58 (2017)
Background and objectives: Hypoxia is an important factor that affects bone formation and regulates bone growth. Therefore, many older adult patients living in high-altitude hypoxic areas exhibit osteoporosis. Oxidative stress-related hypoxia-inducib
Autor:
Hu Li, Guang Yuan Du, Xiao-Ying Yu, Xiao-Meng Gou, Zhen Zhou, Hong-Sheng Zhang, Yang Liu, Zhong-Guo Zhang, Ke-Qing Dai
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 80:51-56
Epigenetic modifications are thought to be important for gene expression changes during HIV-1 transcription and replication. The removal of histone H3 lysine27 (H3K27) trimethylation mark by UTX-1 is important for the robust induction of many specifi