Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zhong-gao GAO"'
Autor:
Zhe-Ao Zhang, Xin Xin, Chao Liu, Yan-hong Liu, Hong-Xia Duan, Ling-ling Qi, Ying-Ying Zhang, He-ming Zhao, Li-Qing Chen, Ming-Ji Jin, Zhong-Gao Gao, Wei Huang
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-24 (2021)
Abstract Background The interactions between nanoparticles (NPs) and plasma proteins form a protein corona around NPs after entering the biological environment, which provides new biological properties to NPs and mediates their interactions with cell
Externí odkaz:
https://doaj.org/article/b0258d874e4d433c8ce24ed9d5502bb7
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 51(2)
Cell membrane serves as the natural barrier. Cell-penetrating peptides(CPPs) have been a powerful vehicle for the intracellular delivery of a large variety of cargoes cross the cell membrane. The efficiency of intracellular delivery of drugs, protein
Autor:
Li-Qing, Chen, Zhe-Ming, Zhang, Wei, Huang, Zhong-Gao, Gao, Wei-Shuo, Fang, Ming-Ji, Jin, Lian, Yu
Publikováno v:
Die Pharmazie. 72(3)
Triple negative breast cancer (TNBC) is a severe breast cancer subtype with the high mortality rate, and still is lack of effective therapeutic means so far. Aziditaxel, a water-insoluble compound, is a novel taxane derivative with strong anti-tumor
Publikováno v:
Chinese Chemical Letters. 26:695-699
Dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt), a cisplatin (CDDP) analog, has shown lower toxicity than CDDP and no cross-resistance with CDDP in many CDDP-resistant cancers. PEGylated hyaluronan (mPEG-HA) is an mPEG conjugated with hyalurona
Autor:
Mei-E, Tan, Cheng-Hui, He, Wen, Jiang, Cheng, Zeng, Ning, Yu, Wei, Huang, Zhong-Gao, Gao, Jian-Guo, Xing
Publikováno v:
International Journal of Nanomedicine
Total flavonoid extract from Dracocephalum moldavica L. (TFDM) contains effective components of D. moldavica L. that have myocardial protective function. However, the cardioprotection function of TFDM is undesirable due to its poor solubility. In ord
Publikováno v:
Journal of Huazhong University of Science and Technology [Medical Sciences]. 34:66-75
This study primarily focused on the systematic assessment of both in vitro and in vivo anti-tumor effects of docetaxel-loaded polyethylene glycol (PEG)2000-polycaprolactone (PCL)2600 micelles on hormone-refractory prostate cancer (HRPC). By using sol
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 38, Iss 9, Pp 714-719 (2013)
Objective To screen the best animal model of hepatic fibrosis reproduced by different drugs and to evaluate the anti-fibrosis activity of Kaishi injection in the chosen animal model. Methods Normal saline (NS), dimethyl nitrosamine (DMN), thiacetamid
Autor:
Wei HUANG, Leung-sang TANG, Yu-li WANG, Zhong-gao GAO, Ying-man SUNG, Hiu-shuen CHAN, Loi-mo FUNG, Hoi-kei KWOK
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 37, Iss 1, Pp 34-39 (2012)
Objective To investigate the effect of single-nucleotide polymorphisms (SNP) -705T>C and -603T>A in the P1 promoter region of human insulin-like growth factor I (IGF-I) gene on promoter activity. Methods A total of 152 healthy volunteers were rec
Publikováno v:
Chinese Chemical Letters. 22:749-752
Copolymers mPEG-PCL were prepared and grafted onto polyethylenimine (PEI) to synthesize copolymers mPEG-PCL-g-PEI with low cytotoxicity. The mPEG-PCL-g-PEI could condense siRNA to form nanoparticles with positive zeta potential. These nanoparticles c
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 36, Iss 5, Pp 437-441 (2011)
Objective To construct(mPEG5k-PCL1.2k)1.4-g-PEI10k,a copolymer designed as delivery vector for non-viral gene therapy,and explore its cytotoxicity and efficacy in delivery of plasmid DNA(pDNA).Methods The copolymer,mPEG5k-PCL1.2k-OH,was prepared by r