Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zhong-Yuan Lyu"'
Autor:
Jiao-Le Fang, Wen-Li Gao, Wei-Feng Xu, Zhong-Yuan Lyu, Lie Ma, Shuai Luo, Xin-Ai Chen, Xu-Ming Mao, Yong-Quan Li
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 4, Pp 1013-1023 (2022)
Despite numerous studies on transcriptional level regulation by single genes in drug producing Actinomyces, the global regulation based on epigenetic modification is not well explored. N4-methylcytosine (m4C), an abundant epigenetic marker in Actinom
Externí odkaz:
https://doaj.org/article/fc233d9e346e4fc092beb08ab7219152
Autor:
Wen-Li Gao, Jiao-Le Fang, Chen-Yang Zhu, Wei-Feng Xu, Zhong-Yuan Lyu, Xin-Ai Chan, Qing-Wei Zhao, Yong-Quan Li
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT DNA methylation is a defense that microorganisms use against extreme environmental stress, and improving resistance against environmental stress is essential for industrial actinomycetes. However, research on strain optimization utilizing DN
Externí odkaz:
https://doaj.org/article/c3b8cff9475640f4a6317dfbde912df3
Autor:
Zhong-Yuan Lyu, Qing-Ting Bu, Jiao-Le Fang, Chen-Yang Zhu, Wei-Feng Xu, Lie Ma, Wen-Li Gao, Xin-Ai Chen, Yong-Quan Li
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Daptomycin is a cyclic lipopeptide antibiotic with a significant antibacterial action against antibiotic-resistant Gram-positive bacteria. Despite numerous attempts to enhance daptomycin yield throughout the years, the production remains unsatisfacto
Externí odkaz:
https://doaj.org/article/00d586c1ec8b4c69a15eb0caf19ab8ec
Autor:
Wei-Feng Xu, Jiao-Le Fang, Qing-Ting Bu, Zhong-Yuan Lyu, Chen-Yang Zhu, Chen-Fan Sun, Qing-Wei Zhao, Yong-Quan Li
Publikováno v:
Applied microbiology and biotechnologyReferences. 106(8)
Daptomycin is a new lipopeptide antibiotic for treatment of severe infection caused by multi-drug-resistant bacteria, but its production cost remains high currently. Thus, it is very important to improve the fermentation ability of the daptomycin pro