Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zhong-Rui Du"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0300787 (2024)
The Presenilin (Psn) gene is closely related to aging, but it is still unclear the role of Psn genes in skeletal muscle. Here, the Psn-UAS/Mhc-GAL4 system in Drosophila was used to regulate muscle Psn overexpression(MPO) and muscle Psn knockdown(MPK)
Externí odkaz:
https://doaj.org/article/1524baf64b404febab5725857b2818a9
Autor:
Xu Cao, Zhong-Rui Du, Xin Liu, Xiong Wang, Chong Li, Sai-Nan Zhou, Jia-Rui Liu, Ping-Yi Xu, Jun-Li Ye, Qing Zhao, Fang Zhao, Ka-Hing Wong, Xiao-Li Dong
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115100- (2023)
The use of oral agents that can modify the gut microbiota (GM) could be a novel preventative or therapeutic option for Parkinson’s disease (PD). Maslinic acid (MA), a pentacyclic triterpene acid with GM-dependent biological activities when it is ta
Externí odkaz:
https://doaj.org/article/35c0cf613f9d48f8aeac9f38b51f55a6
Autor:
Xin Liu, Zhong-Rui Du, Xiong Wang, Kar-Him Luk, Cheuk-Hin Chan, Xu Cao, Qing Zhao, Fang Zhao, Wing-Tak Wong, Ka-Hing Wong, Xiao-Li Dong
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The role of gut-brain axis in the pathogenesis of Parkinson’s disease (PD) have become a research hotspot, appropriate animal model to study gut-brain axis in PD is yet to be confirmed. Our study employed a classical PD mice model achieved by chron
Externí odkaz:
https://doaj.org/article/2bd8e187ea8a4567bf1e02442df5d6e3
Autor:
Xian-Qi Gao, Zhong-Rui Du, Liang-Jie Yuan, Wen-Di Zhang, Lei Chen, Ji-Jun Teng, Man-Sau Wong, Jun-Xia Xie, Wen-Fang Chen
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neuroinflammation plays a pivotal role in the pathogenesis of Parkinson’s disease. Ginsenoside Rg1, the most active ingredient of ginseng, has been reported to exert neuroprotective effects via estrogen and glucocorticoid receptors. The present stu
Externí odkaz:
https://doaj.org/article/6d02e4a03c6d42e0a2ce566c702a6e17
Autor:
Qingjuan Tang, Wing Tak Wong, Changhu Xue, Keith Kwong Hon Wong, Xiao-Li Dong, Qing Zhao, Zhong Rui Du, Xiong Wang, Fang Liu, Robert W. Li, Xin Liu
Publikováno v:
International Journal of Biological Macromolecules. 164:994-1005
The study aims to investigate the potentially neuroprotective effects and underlying mechanisms for brown seaweed polysaccharide of polymannuronic acid (PM) against Parkinson's disease (PD) pathogenesis. PD model mice were pretreated with PM via oral
Autor:
Xin Liu, Zhong Rui Du, Xiong Wang, Xiang Rong Sun, Qing Zhao, Fang Zhao, Wing Tak Wong, Ka Hing Wong, Xiao-Li Dong
Publikováno v:
Food research international (Ottawa, Ont.). 155
Gut microbiota (GM) dysbiosis plays key roles in aggravating Parkinson's disease (PD) and discovery of agents targeting GM may open new avenues for PD therapy. This study aims to investigate the potentially neuroprotective effects and underlying mech
Autor:
Qingjuan Tang, Xin Liu, Xu Cao, Xiong Wang, Sai-Nan Zhou, Hui Zhang, Xiao-Li Dong, Rui-Li Yang, Zhong-Rui Du, Keith Kwong Hon Wong
Publikováno v:
Molecular nutritionfood research. 66(2)
SCOPE This study aims to investigate and compare the potentially neuroprotective effects and underlying mechanisms for brown seaweed polysaccharides (PS) of Alginate (Alg) and its two components, including Polymannuronic acid (PM) and Polyguluronic a
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 214
Neuroinflammation plays an important role in the pathogenesis of Parkinson's disease (PD). Genistein is an estrogen-like phytoestrogen that can exert biological effects via the crosstalk of estrogen receptor and insulin-like growth factor 1 receptor
Autor:
Ji-Jun Teng, Zhong-Rui Du, Liang-Jie Yuan, Xian-Qi Gao, Lei Chen, Jun-Xia Xie, Wen-Fang Chen, Wen-Di Zhang, Man Sau Wong
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience
Frontiers in Neuroscience
Neuroinflammation plays a pivotal role in the pathogenesis of Parkinson’s disease. Ginsenoside Rg1, the most active ingredient of ginseng, has been reported to exert neuroprotective effects via estrogen and glucocorticoid receptors. The present stu
Publikováno v:
European Journal of Pharmacology. 906:174269
Icariin and icaritin, the major active components of Epimedii Genus, are considered as promising drugs with anti-inflammatory, anti-aging and neuroprotective effects. Our previous studies have demonstrated that icariin and icaritin can protect agains