Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Zhong-Qiu Lu"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Diquat (DQ) poisoning can cause multiple organ damage, and the kidney is considered to be the main target organ. Increasing evidence shows that alleviating oxidative stress and inflammatory response has promising application prospects. Epigallocatech
Externí odkaz:
https://doaj.org/article/16070837bd0a41d28d1a92863035fe64
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29156- (2024)
Background: The occurrence and development of sepsis are related to the excessive production of oxygen free radicals and the weakened natural clearance mechanism. Further dependable evidence is required to clarify the effectiveness of antioxidant the
Externí odkaz:
https://doaj.org/article/474b33ea162e4aeba3ecdbbd7466e723
Autor:
Fei Pei, Ren-Qi Yao, Chao Ren, Soheyl Bahrami, Timothy R. Billiar, Irshad H. Chaudry, De-Chang Chen, Xu-Lin Chen, Na Cui, Xiang-Ming Fang, Yan Kang, Wei-Qin Li, Wen-Xiong Li, Hua-Ping Liang, Hong-Yuan Lin, Ke-Xuan Liu, Ben Lu, Zhong-Qiu Lu, Marc Maegele, Tian-Qing Peng, You Shang, Lei Su, Bing-Wei Sun, Chang-Song Wang, Jian Wang, Jiang-Huai Wang, Ping Wang, Jian-Feng Xie, Li-Xin Xie, Li-Na Zhang, Basilia Zingarelli, Xiang-Dong Guan, Jian-Feng Wu, Yong-Ming Yao, the Shock and Sepsis Society of Chinese Research Hospital Association, the China Critical Care Immunotherapy Research Group, the International Federation of the Shock Societies (IFSS)
Publikováno v:
Military Medical Research, Vol 9, Iss 1, Pp 1-18 (2022)
Abstract Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus focusing on the monitoring and
Externí odkaz:
https://doaj.org/article/01bb25699dcd42a4933f034cffbfbeb2
Autor:
Guang-ju Zhao, Dan-wei Jiang, Wen-chao Cai, Xiao-Yan Chen, Wei Dong, Long-wang Chen, Guang-liang Hong, Bin Wu, Yong-ming Yao, Zhong-qiu Lu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundImmune suppression contributes to nosocomial infections (NIs) and poor prognosis in sepsis. Recent studies revealed that CD71+ erythroid cells had unappreciated immunosuppressive functions. This study aimed to investigate the values of CD71
Externí odkaz:
https://doaj.org/article/c54e65205f6341e4b58f6507c8216f0d
Autor:
Guang-ju Zhao, Chang Xu, Jian-chao Ying, Wen-biao Lü, Guang-liang Hong, Meng-fang Li, Bing Wu, Yong-ming Yao, Zhong-qiu Lu
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-9 (2020)
Abstract Background Although current guidelines for AKI suggested against the use of furosemide in AKI management, the effect of furosemide on outcomes in real-world clinical settings remains uncertain. The aim of the present study was to investigate
Externí odkaz:
https://doaj.org/article/367b3c783b29451a8d80e9f4d2d1da4e
Autor:
Jiaming Liu, Yangjie Jin, Yanglie Ye, Yahui Tang, Shanshan Dai, Mengfang Li, Guangju Zhao, Guangliang Hong, Zhong-Qiu Lu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Short chain fatty acids (SCFAs) are known to be actively involved in multiple brain disorders, but their roles in sepsis-associated encephalopathy (SAE) remain unclear. Here, we investigated the neuroprotective effects of SCFAs on SAE in mice. Male C
Externí odkaz:
https://doaj.org/article/a2bd7329910f47e9bf2a576f426d3243
Autor:
Xiu-Ping Xu, Yong-Ming Yao, Guang-Ju Zhao, Zong-Sheng Wu, Jun-Cong Li, Yun-Long Jiang, Zhong-Qiu Lu, Guang-Liang Hong
Publikováno v:
Chinese Medical Journal, Vol 131, Iss 3, Pp 330-338 (2018)
Background: Mitofusin-2 (MFN2), a well-known mitochondrial fusion protein, has been shown to participate in innate immunity, but its role in mediating adaptive immunity remains poorly characterized. In this study, we explored the potential role of MF
Externí odkaz:
https://doaj.org/article/0feb72172e7648f88c13932528f9108c
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Apoptosis of CD4+ T cells plays a central role in the progression of sepsis because it is associated with subsequent immunosuppression and the lack of specific treatment. Thus, developing therapeutic strategies to attenuate the apoptosis of CD4+ T ce
Externí odkaz:
https://doaj.org/article/29d1e7a9a841419b96113d56ac56b38d
Autor:
Lan Ying, Guang-Ju Zhao, You Wu, He-Liang Ke, Guang-Liang Hong, Hui Zhang, Ning Dong, Yao Wu, Yong-Ming Yao, Zhong-Qiu Lu
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Apoptosis of CD4+ T cells is a primary pathophysiological mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer membrane protein, has been confirmed to be associated with cellular metabolis
Externí odkaz:
https://doaj.org/article/73d339c92d40462fb437dc9a993ee775
Autor:
Guang-ju Zhao, Jia-yi Zheng, Jia-lan Bian, Long-wang Chen, Ning Dong, Yan Yu, Guang-liang Hong, Arvine Chandoo, Yong-Ming Yao, Zhong-qiu Lu
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Background. Growth arrest-specific (Gas) 6 is one of the endogenous ligands of TAM receptors (Tyro3, Axl, and Mertk), and its role as an immune modulator has been recently emphasized. Naturally occurring CD4+CD25+ regulatory T cells (Tregs) are essen
Externí odkaz:
https://doaj.org/article/20ac27002ad0474982302e2599ab9f32