Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Zhong-Fu Zuo"'
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-25 (2024)
Abstract Objective To investigate the effect of salidroside (SAL) in protecting retinal ganglion cell (RGC) from pyroptosis and explore associated molecular network mechanism in diabetic retinapathy (DR) rats. Methods HE, Nissl and immunofluorescence
Externí odkaz:
https://doaj.org/article/5ca08b397c1745588ec229ad9f6d386a
Autor:
Lang-Chun Zhang, Na Li, Ji-Lin Chen, Jie Sun, Min Xu, Wen-Qiang Liu, Zhong-Fu Zuo, Lan-Lan Shi, Ting-Hua Wang, Xiang-Yin Luo
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e27508- (2024)
Objective: To explore the effect of human urine-derived stem cells (husc) in improving the neurological function of rats with cerebral ischemia-reperfusion (CIR), and report new molecular network by bioinformatics, combined with experiment validation
Externí odkaz:
https://doaj.org/article/d527cb302436488fafbb499207a36185
Autor:
Liu-Lin Xiong, Yi-Fei Sun, Rui-Ze Niu, Lu-Lu Xue, Li Chen, Li-Ren Huangfu, Jing Li, Yu-Ying Wang, Xin Liu, Wen-Yuan Wang, Zhong-Fu Zuo, Ting-Hua Wang
Publikováno v:
Research, Vol 7 (2024)
Tree shrews (TSs) possess a highly developed visual system. Here, we establish an age-related single-cell RNA sequencing atlas of retina cells from 15 TSs, covering 6 major retina cell classes and 3 glial cell types. An age effect is observed on the
Externí odkaz:
https://doaj.org/article/d31b47c4586b42e087b0e5b03acbfc44
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Purpose: Diabetic retinopathy (DR) is a serious complication of diabetes mellitus, which nearly happens to all the diabetic sufferers. This study aims to identify the preliminary molecular regulation involved in the therapeutic efficacy of astragalos
Externí odkaz:
https://doaj.org/article/c1270cd4d47d4554a349d1dd3fa70e48
Publikováno v:
Ibrain, Vol 6, Iss 3, Pp 24-33 (2020)
Objective To explore the potential molecular network mechanism of coptidis rhizoma in the treatment of spinal cord injury (SCI) based on network pharmacology and molecular docking technology. Methods The compounds of coptidis rhizoma and therapeutic
Externí odkaz:
https://doaj.org/article/9c4a5c1bcafd4eb8a4a3c904bbbcc096
Publikováno v:
Guoji Yanke Zazhi, Vol 17, Iss 3, Pp 418-421 (2017)
AIM: To investigate the detrimental effect of glucocorticoid(GC)on the retinal neurons of diabetes mellitus(DM)rats.METHODS: The DM model was induced by intraperitoneal injection(IP)of streptozotocin in adult male rats, and the solution of RU486 was
Externí odkaz:
https://doaj.org/article/baaa804b0e744295a8cf92373e8b7016
Publikováno v:
Guoji Yanke Zazhi, Vol 17, Iss 2, Pp 217-220 (2017)
AIM: To investigate the effect of NgR mediated oxidative stress on the apoptosis of retinal ganglion cells(RGCs)induced by glucose. METHODS: RGC-5 cell were divided into 3 groups: control group(DMEM high glucose medium+10% fetal calf serum), high glu
Externí odkaz:
https://doaj.org/article/46bda839570e4713ab3b5c6a7e87a884
Publikováno v:
Guoji Yanke Zazhi, Vol 14, Iss 5, Pp 807-810 (2014)
AIM:To investigate the protective effects of pEGFP/ Ang-1 transfected BMSCs on RF/6A in condition of high glucose concentration. METHODS: BMSCs were transfected pEGFP/Ang-1, confirming by observation of enhanced green fluorescent protein(EGFP)with fl
Externí odkaz:
https://doaj.org/article/9f2900d5589f411b86bc03e769d97017
Publikováno v:
International Journal of Ophthalmology, Vol 6, Iss 4, Pp 422-424 (2013)
AIM: To explore the effects and potential mechanisms of curcumin on retinal Müller cell in early diabetic rats.METHODS: Diabetic rats were induced by a single intraperitoneal injection of streptozotocin (STZ). Male Sprague-Dawley (SD) rats were rand
Externí odkaz:
https://doaj.org/article/5d89d50dbdd84288b82fb4fb17ae8645
Publikováno v:
Guoji Yanke Zazhi, Vol 13, Iss 7, Pp 1317-1319 (2013)
AIM: To explore the role and underlying mechanisms of nogo receptor(NgR)on the apoptosis of retinal ganglion cell in rats with diabetes mellitus(DM).METHODS: SD rats were used for inducing DM models by administrating streptozotocin. Studies were perf
Externí odkaz:
https://doaj.org/article/9691f0f4f6dd483f8f6a1502e4166f37