Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Zhong-Dong Shi"'
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 11, Pp 1378-1388 (2020)
Abstract Human pluripotent stem cells, including induced pluripotent stem cells (iPSCs) and embryonic stem cells, hold great promise for cell‐based therapies, but safety concerns that complicate consideration for routine clinical use remain. Instal
Externí odkaz:
https://doaj.org/article/45ae7e2babc84ed08a807db73aab8c50
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1103-1111 (2015)
The development of new gene-editing tools, in particular the CRISPR/Cas system, has greatly facilitated site-specific mutagenesis in human embryonic stem cells (hESCs), including the introduction or correction of patient-specific mutations for diseas
Externí odkaz:
https://doaj.org/article/7eefbed17c1f4feaa9f806e1d4c754bd
Autor:
Dapeng Yang, Hyunwoo Cho, Zakieh Tayyebi, Abhijit Shukla, Renhe Luo, Gary Dixon, Valeria Ursu, Stephanie Stransky, Daniel M. Tremmel, Sara D. Sackett, Richard Koche, Samuel J. Kaplan, Qing V. Li, Jiwoon Park, Zengrong Zhu, Bess P. Rosen, Julian Pulecio, Zhong-Dong Shi, Yaron Bram, Robert E. Schwartz, Jon S. Odorico, Simone Sidoli, Christopher V. Wright, Christina S. Leslie, Danwei Huangfu
Publikováno v:
Nat Cell Biol
The pancreas and liver arise from a common pool of progenitors. However, the underlying mechanisms that drive their lineage diversification from the foregut endoderm are not fully understood. To tackle this question, we undertook a multifactorial app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0968b715c0f7a68ebc3d46f571086a1
https://europepmc.org/articles/PMC9283336/
https://europepmc.org/articles/PMC9283336/
Autor:
Federico González, Daniela Georgieva, Fabio Vanoli, Zhong-Dong Shi, Matthias Stadtfeld, Thomas Ludwig, Maria Jasin, Danwei Huangfu
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 651-660 (2013)
Induced pluripotent stem cells (iPSCs) hold great promise for personalized regenerative medicine. However, recent studies show that iPSC lines carry genetic abnormalities, suggesting that reprogramming may be mutagenic. Here, we show that the ectopic
Externí odkaz:
https://doaj.org/article/42225dc0d06f426aa70d80c381455699
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15956 (2011)
Interstitial flow directly affects cells that reside in tissues and regulates tissue physiology and pathology by modulating important cellular processes including proliferation, differentiation, and migration. However, the structures that cells utili
Externí odkaz:
https://doaj.org/article/3c157f17bb0a48178ce7c11e9ccb32a1
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20348 (2011)
Glioma cells are exposed to elevated interstitial fluid flow during the onset of angiogenesis, at the tumor periphery while invading normal parenchyma, within white matter tracts, and during vascular normalization therapy. Glioma cell lines that have
Externí odkaz:
https://doaj.org/article/364557481fca438180297f03d5468b27
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12196 (2010)
During vascular injury, vascular smooth muscle cells (SMCs) and fibroblasts/myofibroblasts (FBs/MFBs) are exposed to altered luminal blood flow or transmural interstitial flow. We investigate the effects of these two types of fluid flows on the pheno
Externí odkaz:
https://doaj.org/article/e8e28771dc6a48d3ba62f42b2e2dc03b
Publikováno v:
PLoS ONE. 2011, Vol. 6 Issue 5, p1-13. 13p.
Autor:
Jonathan W. Song, Ye Zeng, Lance L. Munn, Peigen Huang, Limary M. Cancel, John M. Tarbell, Sylvie Roberge, Zhong-Dong Shi, Henry Qazi
Publikováno v:
International Journal of Cancer. 139:2791-2801
The surface proteoglycan/glycoprotein layer (glycocalyx) on tumor cells has been associated with cellular functions that can potentially enable invasion and metastasis. In addition, aggressive tumor cells with high metastatic potential have enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c09ec0ceef92afcf4f1b7a41276493b
https://doi.org/10.1002/ijc.30397
https://doi.org/10.1002/ijc.30397
Publikováno v:
Biotechnology and bioengineering. 116(10)
It is widely believed that the differentiation of embryonic stem cells (ESCs) into viable endothelial cells (ECs) for use in vascular tissue engineering can be enhanced by mechanical forces. In our previous work, we reported that shear stress enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cbfa3d300d14eb084c33b459b75703
https://pubmed.ncbi.nlm.nih.gov/31282995
https://pubmed.ncbi.nlm.nih.gov/31282995