Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zhong-Cheng Song"'
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 8, Pp o1999-o1999 (2011)
In the title compound, C16H16ClN, the dihedral angle between the benzene rings is 24.61 (13)°. In the crystal, only van der Waals interactions occur between neighbouring molecules.
Externí odkaz:
https://doaj.org/article/0a14f67ffa354629914a4ffa2b054a5e
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 4, Pp o947-o947 (2011)
The title compound, C11H8O3, was isolated from Impatiens balsamina plants (balsam, LIB) grown in our laboratory. The two six-membered rings of the naphthalene-1,4-dione unit are coplanar [maximum deviation = 0.009 (1) Å]. The O and C atoms of the me
Externí odkaz:
https://doaj.org/article/d25e24beffbd41afa3bb9ce3f73086b4
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 1, Pp e10-e10 (2011)
The author list in the paper by Ding [Acta Cryst. (2010), E66, o2633] is corrected.
Externí odkaz:
https://doaj.org/article/d9e1f795fc25400b848f484fb7f5fbd3
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 11, Pp o2934-o2934 (2010)
In the title compound, C15H18ClNO4S·H2O, the thiazolidine ring displays a half-chair conformation. In the crystal, the water molecules are linked to the organic acid molecules via intermolecular O—H...O hydrogen bonds.
Externí odkaz:
https://doaj.org/article/e7c13d11743b4a5b80daab38835489f5
Autor:
Xun Wu, Shao Sha, Yong Yin, Yang Zhou, Hai-Liang Zhu, Zhong-Cheng Song, Fang Qiao, She-Feng Wang
Publikováno v:
Bioorganic chemistry. 92
PI3K pathway has been heavily studied and is one of the most potential targets for various cancer treatment. Herein, we designed and synthesized a series of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates contained piperazine based on our previous r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3bbf4265b935344b206cf7d377a3b6
https://pubmed.ncbi.nlm.nih.gov/31499259
https://pubmed.ncbi.nlm.nih.gov/31499259
Publikováno v:
European journal of medicinal chemistry. 182
PI3K signal pathway plays a vital role in cellular functions and becomes an attractive approach for cancer therapy. Herein, a new series of novel chromeno[4,3-c]pyrazol-4(2H)-one derivatives bearing sulfonylpiperazine based on the PI3K inhibitors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e668791c997c24655c42174b352953
https://pubmed.ncbi.nlm.nih.gov/31446244
https://pubmed.ncbi.nlm.nih.gov/31446244
Autor:
Fang Qiao, She-Feng Wang, Hai-Liang Zhu, Shao Sha, Xu Wu, Jia-Qin Hu, Zhong-Cheng Song, Yong Yin
Publikováno v:
Bioorganicmedicinal chemistry. 27(11)
A series of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates contained sulfonamido were designed and synthesized, and their anticancer effects in vitro was evaluated to develop some new PI3Kα inhibitors. Most of desired compounds exhibited the bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9133e44e3e7108e06973473c7c655cb7
https://pubmed.ncbi.nlm.nih.gov/31029551
https://pubmed.ncbi.nlm.nih.gov/31029551
Publikováno v:
RSC Advances. 5:24824-24833
A possible mechanism of dynamic kinetic resolution by the formation of N-tert-butoxycarbonyl-thiazolidine carboxylic acid was proposed and validated by a quantitative density functional theoretical calculation according to Curtin–Hammett principle.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::501a0a478805dee404ed04f853cf744a
https://doi.org/10.1039/c4ra15284k
https://doi.org/10.1039/c4ra15284k
Autor:
Zhong-Cheng Song, Hai-Liang Zhu
Publikováno v:
Expert Opinion on Therapeutic Patents. 21:593-600
The verification of refined variants of already existing medicines proved to be a breakthrough for antibiotic research. However, resistance to old and newer antibiotics among microbacillary pathogens is evolving quickly. Drug-resistant pathogens have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede59e0e4b098ca65c1a8a34eec649f8
https://doi.org/10.1517/13543776.2011.560571
https://doi.org/10.1517/13543776.2011.560571
Publikováno v:
European Journal of Medicinal Chemistry. 44:3903-3908
Nine 2-arylthiazolidine-4-carboxylic acid derivatives and nine 3-tert-butoxycarbonyl-2-arylthiazolidine-4-carboxylic acid derivatives were synthesized to screen for their antibacterial activities. Compounds 5, 14–18 were first reported. Their chemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5e9697c208337fdeca045172b68a44
https://doi.org/10.1016/j.ejmech.2009.04.014
https://doi.org/10.1016/j.ejmech.2009.04.014