Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zhong Yan Gan"'
Publikováno v:
Cell Death and Differentiation
Neurodegenerative diseases are characterised by progressive damage to the nervous system including the selective loss of vulnerable populations of neurons leading to motor symptoms and cognitive decline. Despite millions of people being affected worl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fcc343ae99d7ec9daaf7afc5d1c6f7
http://europepmc.org/articles/PMC7862249
http://europepmc.org/articles/PMC7862249
Autor:
Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander
Publikováno v:
Nature. 602(7896)
Mutations in the protein kinase PINK1 lead to defects in mitophagy and cause autosomal recessive early onset Parkinson's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6588c3951991931576f31094feab91db
https://pubmed.ncbi.nlm.nih.gov/35293391
https://pubmed.ncbi.nlm.nih.gov/35293391
Autor:
Zhong Yan Gan, Sylvie Callegari, Simon A. Cobbold, Thomas R. Cotton, Michael J. Mlodzianoski, Alexander F. Schubert, Niall D. Geoghegan, Kelly L. Rogers, Andrew Leis, Grant Dewson, Alisa Glukhova, David Komander
Publikováno v:
Nature. 603:E33-E33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b24df92c26e971998cad502fd60dbf68
https://doi.org/10.1038/s41586-022-04591-7
https://doi.org/10.1038/s41586-022-04591-7
Autor:
Timothy R Blackmore, Zhong Yan Gan, Rebecca Feltham, Bernhard C. Lechtenberg, Jonathan P. Bernardini, Alan Riboldi-Tunnicliffe, Gregor Ebert, Cody C. Allison, Lachlan W Richardson, David Komander, Huib Ovaa, Theresa Klemm, Marc Pellegrini, Nathan W Kuchel, Guillaume Lessene, Kym N Lowes, Christoph Grohmann, Jeffrey P Mitchell, James P Cooney, Gerbrand J. van der Heden van Noort, Paul P. Geurink, Amanda E. Au, Grant Dewson, Marcel Doerflinger, Dale J Calleja, Peter E. Czabotar, Bernadine Gc Lu, Yuri Shibata, Janet Newman
Publikováno v:
EMBO Journal, 39(18). WILEY
The EMBO Journal
The EMBO Journal
The SARS‐CoV‐2 coronavirus encodes an essential papain‐like protease domain as part of its non‐structural protein (nsp)‐3, namely SARS2 PLpro, that cleaves the viral polyprotein, but also removes ubiquitin‐like ISG15 protein modifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36f05a4438244e4379d16ac47d20c92
https://hdl.handle.net/1887/3182567
https://hdl.handle.net/1887/3182567
Autor:
Christoph Grohmann, Lu Bgc, Jonathan P. Bernardini, Huib Ovaa, Cody C. Allison, Gregor Ebert, Guillaume Lessene, Rebecca Feltham, Dale J Calleja, Marc Pellegrini, David Komander, T. Klemm, Mitchell Jp, Kym N Lowes, Bernhard C. Lechtenberg, James P Cooney, Peter E. Czabotar, Amanda E. Au, Zhong Yan Gan, Paul P. Geurink, Kuchel Nw, Janet Newman, Yuri Shibata, Blackmore Tr, L.W. Richardson, Grant Dewson, Marcel Doerflinger, Alan Riboldi-Tunnicliffe
Coronaviruses, including SARS-CoV-2, encode multifunctional proteases that are essential for viral replication and evasion of host innate immune mechanisms. The papain-like protease PLpro cleaves the viral polyprotein, and reverses inflammatory ubiqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf71356e1581ef4bb08f30febabebb6e
https://doi.org/10.1101/2020.06.18.160614
https://doi.org/10.1101/2020.06.18.160614
Autor:
Marcel P. Bruchez, Harshad Ghodke, Nicholas E. Dixon, Matharishwan Naganbabu, Antoine M. van Oijen, Slobodan Jergic, Zhong Yan Gan, Gurleen Kaur, Stefan H. Mueller, Hamish Maynard, Kelsey S. Whinn, Jacob S. Lewis, Mike O'Donnell, Grant D Schauer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
DNA replication occurs on chromosomal DNA while processes such as DNA repair, recombination and transcription continue. However, we have limited experimental tools to study the consequences of collisions between DNA-bound molecular machines. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb3f37a7cc77624c05ed27b77efd6af