Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Zhong Wen Yuan"'
Autor:
Hong-Liu Jin, Xiao-Jia Liu, Xiao-Ying Feng, Wen-Ting Zhu, Sen-Ling Feng, Li-Ping Cao, Zhong-Wen Yuan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Objective: To explore the pharmacological effects and molecular mechanism of quercetin 7-rhamnoside (Q7R) in the treatment of cholestatic hepatitis induced by alpha-naphthylisothiocyanate (ANIT).Methods: ANIT-induced cholestatic hepatitis rat model w
Externí odkaz:
https://doaj.org/article/5ba47d1e25da41188ad469bb0ca271f9
Autor:
Jing-Bei Zhang, Hong-Liu Jin, Xiao-Ying Feng, Sen-ling Feng, Wen-Ting Zhu, Hong-Mei Nan, Zhong-Wen Yuan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: To explore the active components and epigenetic regulation mechanism underlying the anti-inflammatory effects of Lonicerae Japonicae Flos and Forsythiae Fructus herb-pair (LFP) in carbon tetrachloride (CCl4)-induced rat liver fibrosis.Meth
Externí odkaz:
https://doaj.org/article/3845cb2944c546aeba7f7ce53ef4e2b2
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Although hepatoprotective properties of silybin are well documented, the clinical therapeutic efficacy is limited by its low bioavailability due to absorption rates, extensive phase II metabolism, and biliary excretion. As our previous study indicate
Externí odkaz:
https://doaj.org/article/96568bdf631743038f5c02036dc8a995
Autor:
Zhong‐Wen Yuan, Hai‐Ling Gan, Hong‐Liu Jin, Xiao‐Ying Feng, Ming Wang, Hua‐Ping Zhou, Jing Zhang
Publikováno v:
Journal of Clinical Laboratory Analysis. 37
Acquired immune deficiency syndrome (AIDS), human immunodeficiency virus (HIV) infection, and antiretroviral therapy are usually associated with metabolic disorders. Screening for biomarkers to evaluate the progression of metabolic disorders is impor
Autor:
Jing-Bei, Zhang, Hong-Liu, Jin, Xiao-Ying, Feng, Sen-Ling, Feng, Wen-Ting, Zhu, Hong-Mei, Nan, Zhong-Wen, Yuan
Publikováno v:
Frontiers in pharmacology. 13
Autor:
Zhen-Hua Li, Dong-Dong Jing, Yi-Qing Chen, Cai-Yan Lin, Zhong-Qiu Liu, Yuan-Yuan Cheng, Zhong-Wen Yuan, Wen-Ting Zhu, Lian-Di Chen, Peng-Ke Yan
Publikováno v:
Atherosclerosis. 297:64-73
Background and aims Atherosclerosis is a serious cardiovascular disease, featuring inflammation, abnormal proliferation and migration of vascular smooth muscle cells (VSMCs). During atherosclerosis, inflammation may cause low pH. T-cell death-associa
Autor:
David C. Ward, Fu Gang Duan, Ying Xie, Zhongqiu Liu, Liang Liu, Elaine Lai-Han Leung, Dan Feng Shi, Jian Ding, Xiao Jun Yao, Lan Lan Li, Lin Lin Lu, Min Huang, Xing Xing Fan, Lian Xiang Luo, Zhong Wen Yuan, Ying Li, Ju-Min Huang
Publikováno v:
International Journal of Cancer. 145:1334-1345
Oncogenic KRAS is considered a promising target for anti-cancer therapy. However, direct pharmacological strategies targeting KRAS-driven cancers remained unavailable. The prenyl-binding protein PDEδ, a transporter of KRAS, has been identified as a
Publikováno v:
International Journal of Nanomedicine
Yi-Qing Chen,* Wen-Ting Zhu,* Cai-Yan Lin, Zhong-Wen Yuan, Zhen-Hua Li, Peng-Ke Yan The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, People’s Republic of China*These authors contributed equally to this workCorrespond
Autor:
Xiao-Jun Zhang, Xiu-Ting Yu, Yao-Xing Dou, Ping Vicky Chen, Tao Huang, Hui-Fang Zeng, Ying Xie, Zhong-Wen Yuan, Jian-Nan Chen, Jia-Zhen Wu, Zi-Ren Su, Chang Qu
Publikováno v:
Pharmacological Research. 137:34-46
Inflammatory bowel disease (IBD), majorly include Crohn’s disease (CD) and ulcerative colitis (UC), is chronic and relapsing inflammatory disorders of the gastrointestinal tract, which treatment options remain limited. Here we examined the therapeu
Autor:
Ying Xie, Hua Zhou, Liang Liu, Senling Feng, Ya-Zhuo Li, Zhong-Wen Yuan, Zhongqiu Liu, Chang-Xiao Liu
Publikováno v:
Pharmacological Research. 128:153-166
Biological responses of a variety of naturally occurring compounds in vivo were restrained by their poor oral bioavailability. Silybin, as one of the active ingredients of silymarin, has presented promising bioactivity for the treatment of chronic li