Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zhong Sheng Ji"'
Autor:
Jia, Pu, Liang, Jie-Liang, Lu, Jing-li, Zhong, Sheng-ji, Xiong, Tian, Feng, Shi-wei, Wang, Yutao, Wu, Zhuo-hui, Yi, Xin-zhu, Gao, Shao-ming, Zheng, Jin, Wen, Ping, Li, Fenglin, Li, Yanying, Liao, Bin, Shu, Wen-sheng, Li, Jin-tian
Publikováno v:
In Environment International September 2024 191
Akademický článek
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Autor:
Yi, Xinzhu, Liang, Jie-Liang, Wen, Ping, Jia, Pu, Feng, Shi-wei, Liu, Shen-yan, Zhuang, Yuan-yue, Guo, Yu-qian, Lu, Jing-li, Zhong, Sheng-ji, Liao, Bin, Wang, Zhang, Shu, Wen-sheng, Li, Jin-tian
Publikováno v:
Nature Communications; 8/30/2024, Vol. 15 Issue 1, p1-15, 15p
Autor:
Robert W. Mahley, Zhong-Sheng Ji
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 1, Pp 1-16 (1999)
The plasma clearance of intestinally derived remnant lipoproteins by the liver is a process that likely involves three steps. Our model suggests that the initial rapid clearance by the liver begins with sequestration of the remnants within the space
Externí odkaz:
https://doaj.org/article/825795ce2fb040cea5c1a78dde2d57bb
Autor:
Zhong Sheng Ji, Maureen E. Balestra, Michael A. Pleiss, Dah Eun Jeong, Anke Meyer-Franke, Qin Xu, David W. Walker, Zhaoping Liu, Karl H. Weisgraber, Yadong Huang, John C. Voss, Stephen B. Freedman, Jens Brodbeck, Rene D. Miranda, Hung Kai Chen, James G. McGuire, Madhu S. Budamagunta, Robert W. Mahley
Publikováno v:
Journal of Biological Chemistry. 287:5253-5266
Apolipoprotein E4 (apoE4), the major genetic risk factor for late onset Alzheimer disease, assumes a pathological conformation, intramolecular domain interaction. ApoE4 domain interaction mediates the detrimental effects of apoE4, including decreased
Autor:
R. Dennis Miranda, Karin Mullendorff, Zhong Sheng Ji, Yadong Huang, Irene H. Cheng, Robert W. Mahley
Publikováno v:
Journal of Biological Chemistry. 281:2683-2692
We previously demonstrated that apolipoprotein E4 (apoE4) potentiates lysosomal leakage and apoptosis induced by amyloid β (Aβ) peptide in cultured Neuro-2a cells and hypothesized that the low pH of lysosomes accentuates the conversion of apoE4 to
Autor:
Zhong-Sheng Ji, Tu T. Nguyen, Robert W. Mahley, Thomas B. Crotty, Kent E. Kruckeberg, Timothy O'Brien, Ian D. Hay, John F. O'Brien, Pamela S. Karnes
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:4354-4358
Splenomegaly with sea-blue histiocytes is not associated with dyslipidemia, except in severe cases of hypertriglyceridemia, Tangier disease, or lecithin cholesterol acyltransferase deficiency. We describe two kindreds in which the sea-blue histiocyte
Autor:
Zhong-Sheng Ji, Robert W. Mahley, Yadong Huang, John M. Taylor, Walter J. Brecht, Stanley C. Rall
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 19:2952-2959
Abstract —The differential effects of overexpression of human apolipoprotein (apo) E3 on plasma cholesterol and triglyceride metabolism were investigated in transgenic rabbits expressing low (20 mg/dL) levels of apoE3. Cholesterol levels increased
Autor:
Robert W. Mahley, H. V. De Silva, Jianglin Fan, Thomas L. Innerarity, Yadong Huang, David A. Sanan, John M. Taylor, Zhong Sheng Ji
Publikováno v:
Journal of Clinical Investigation. 101:2151-2164
Transgenic rabbits expressing human apo E3 were generated to investigate mechanisms by which apo E modulates plasma lipoprotein metabolism. Compared with nontransgenic littermates expressing approximately 3 mg/dl of endogenous rabbit apo E, male tran
Publikováno v:
Journal of Biological Chemistry. 273:13452-13460
Isoform-specific effects of apolipoprotein E (apoE) on neurite outgrowth and the cytoskeleton are associated with higher intracellular levels of apoE3 than apoE4 in cultured neurons. The current studies, designed to determine the mechanism for the di