Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Zhong Ping Feng"'
SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice
Autor:
Mengjia Huang, Chun Hin Chow, Akshay Gurdita, Hidekiyo Harada, Victor Q. B. Pham Truong, Sarah Eide, Hong-Shuo Sun, Zhong-Ping Feng, Philippe P. Monnier, Valerie A. Wallace, Shuzo Sugita
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract SNARE-mediated vesicular transport is thought to play roles in photoreceptor glutamate exocytosis and photopigment delivery. However, the functions of Synaptosomal-associated protein (SNAP) isoforms in photoreceptors are unknown. Here, we re
Externí odkaz:
https://doaj.org/article/b9879e6b53ed4557a4ce88532d44b2b2
Autor:
Ye Peng, Jun-rui Ye, Sha-sha Wang, Wen-bin He, Zhong-ping Feng, Hong-shuo Sun, Shi-feng Chu, Zhao Zhang, Nai-hong Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-17 (2023)
Abstract Parkinson’s disease (PD) is pathologically manifested by the aggregation of α-synuclein, which has been envisioned as a promising disease-modifying target for PD. Here, we identified 20C, a bibenzyl compound derived from Gastrodia elata,
Externí odkaz:
https://doaj.org/article/c502ea60b4eb41b9afd18262f3212636
Autor:
Alicia N Harracksingh, Julia Bandura, Takefumi Morizumi, Philippe P Monnier, Jeffrey T Henderson, Zhong-Ping Feng
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313407 (2024)
Optic photoreception is a critical function for animal survival. Across the evolutionary spectrum, diverse animal models have been used to investigate visual system function and potential mechanisms under physiological or pathophysiological states. H
Externí odkaz:
https://doaj.org/article/4502d70994b24ffda619c0842186fcde
Autor:
Wen-yu Ma, Qing-lin Wu, Sha-sha Wang, Hong-yun Wang, Jun-rui Ye, Hong-shuo Sun, Zhong-ping Feng, Wen-bin He, Shi-feng Chu, Zhao Zhang, Nai-hong Chen
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-23 (2023)
Abstract Ischemic stroke is characterized by the presence of reactive microglia. However, its precise involvement in stroke etiology is still unknown. We used metabolic profiling and showed that chemokine like factor 1 (CKLF1) causes acute microglial
Externí odkaz:
https://doaj.org/article/7f8bc31b84224e17b6bcd65f5948714d
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100635- (2023)
Huntington's disease (HD) is a rare, inherited disorder with a broad spectrum of manifestations that vary with disease severity and progression. Although genetic testing can readily confirm the initial diagnosis of HD, markers sensitive to HD progres
Externí odkaz:
https://doaj.org/article/d4a9bb2892ba45f6bf6403d573b3b160
Autor:
Mengjia Huang, Na-Ryum Bin, Jayant Rai, Ke Ma, Chun Hin Chow, Sarah Eide, Hidekiyo Harada, Jianbing Xiao, Daorong Feng, Hong-Shuo Sun, Zhong-Ping Feng, Herbert Y. Gaisano, Jeffrey E. Pessin, Philippe P. Monnier, Kenichi Okamoto, Liang Zhang, Shuzo Sugita
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106664- (2023)
Summary: SNARE-mediated membrane fusion plays a crucial role in presynaptic vesicle exocytosis and also in postsynaptic receptor delivery. The latter is considered particularly important for synaptic plasticity and learning and memory, yet the identi
Externí odkaz:
https://doaj.org/article/3e434672cf0e4a088f5a59acf5406521
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Objective: Therapeutic hypothermia (TH) is the current standard of care for neonatal hypoxic-ischemic encephalopathy (HIE), yet morbidity and mortality remain significant. Adjuvant neuroprotective agents have been suggested to augment hypothermic-med
Externí odkaz:
https://doaj.org/article/ab7c7dc6360f424a83f4119e033eb693
Autor:
Weihong Zhou, Spencer Eckler, Andrew Barszczyk, Alex Waese-Perlman, Yingjie Wang, Xiaoping Gu, Zhong-Ping Feng, Yuzhu Peng, Kang Lee
Publikováno v:
BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Waist circumference is becoming recognized as a useful predictor of health risks in clinical research. However, clinical datasets tend to lack this measurement and self-reported values tend to be inaccurate. Predicting waist circu
Externí odkaz:
https://doaj.org/article/7d8a37f922f5412ba49655f7322a5602
Autor:
Nancy Dong, Julia Bandura, Zhaolei Zhang, Yan Wang, Karine Labadie, Benjamin Noel, Angus Davison, Joris M. Koene, Hong-Shuo Sun, Marie-Agnès Coutellec, Zhong-Ping Feng
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background The pond snail Lymnaea stagnalis (L. stagnalis) has been widely used as a model organism in neurobiology, ecotoxicology, and parasitology due to the relative simplicity of its central nervous system (CNS). However, its usefulness
Externí odkaz:
https://doaj.org/article/42deca5416ba433e8c9820699cea952f
Publikováno v:
Frontiers in Digital Health, Vol 3 (2021)
Regular blood pressure (BP) monitoring enables earlier detection of hypertension and reduces cardiovascular disease. Cuff-based BP measurements require equipment that is inconvenient for some individuals and deters regular home-based monitoring. Sinc
Externí odkaz:
https://doaj.org/article/f9201cd68cd349bca01ee753d037c899