Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zhong Fu Huang"'
Autor:
Yanyun Liu, Kenny Tsang, Michelle Mays, Gale Hansen, Jeffrey Chiecko, Maureen Crames, Yangjie Wei, Weijie Zhou, Chase Fredrick, James Hu, Dongmei Liu, Douglas Gebhard, Zhong-Fu Huang, Akshita Datar, Anthony Kronkaitis, Kristina Gueneva-Boucheva, Daniel Seeliger, Fei Han, Saurabh Sen, Srinath Kasturirangan, Justin M. Scheer, Andrew E. Nixon, Tadas Panavas, Michael S. Marlow, Sandeep Kumar
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Biotherapeutic optimization, whether to improve general properties or to engineer specific attributes, is a time-consuming process with uncertain outcomes. Conversely, Consensus Protein Design has been shown to be a viable approach to enhance protein
Externí odkaz:
https://doaj.org/article/4c91351f25cc410584aa768aeb4853a4
Publikováno v:
Discrete & Continuous Dynamical Systems - B. 26:1111-1127
The purpose of the paper is to investigate the flocking behavior of the discrete-time Cucker-Smale(C-S) model under general interaction network topologies with agents having their free-will accelerations. We prove theoretically that if the free-will
Autor:
Michael Dziegelewski, David Presky, Susan van Tongeren, Steve Fogal, Rachel Kroe-Barrett, Helen Wu, Sanjaya Singh, Tobias Litzenberger, Scott Brodeur, Gale Hansen, Christine Grimaldi, Eliud Sepuldeva, Zhong-Fu Huang, Dongmei Liu, Hua Li, Kerry-Leigh Ralph, Lee Frego, Jennifer Ahlberg
Publikováno v:
International Journal of Pharmaceutics. 609:121162
Antibodies targeting the CD40-CD40L pathway have great potential for treating autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus (SLE), lupus nephritis (LN), and inflammatory bowel diseases (IBD). However, in addition to the
Autor:
Maria Myzithras, Erica Waltz, Irina Rybina, Zhong-Fu Huang, Jennifer Ahlberg, Tammy Bigwarfe, Haiguang Xiao, Rachel Kroe-Barrett, Marcio O. Lasaro, Himanshu Saraf, Simon Roberts, Cynthia Hess Kenny, Danlin Yang, Steven Castellano, Sanjaya Singh, Craig Giragossian
Publikováno v:
mAbs
Antibodies with pH-dependent binding to both target antigens and neonatal Fc receptor (FcRn) provide an alternative tool to conventional neutralizing antibodies, particularly for therapies where reduction in antigen level is challenging due to high t
Publikováno v:
Advanced Materials Research. :1222-1227
The tensile tests of DP590 dual-phase steel tailor-welded blanks were carried out at different temperatures and strain rates. Quantitative analysis of metallographic was utilized to study the microstructure evolution of the base metal area and the we
Publikováno v:
Materials Science Forum. 682:159-165
Severe plastic deformation (SPD) can refine conventional coarse-grained materials to submicrometer or even nanometer level. In this paper, effective strain distribution was simulated by rigid-plastic finite element method (FEM) after multi-pass cycli
Publikováno v:
Advanced Materials Research. :2675-2679
Based on empirical analysis and FEA modeling of multi-stage sheet metal stamping, the optimal sheet metal stamping process can be supplied. Concurrently, the effects of process parameters on formability are found by numerical simulation. Taking an ex
Publikováno v:
Advanced Materials Research. :1855-1858
It is well known that the design of multi-step sheet metal forming process is rather difficult. Even small errors may cause significant quality problem. In recent years, finite element analysis (FEA) has being considered as an essential tool for the
Autor:
Zheng Feng Yin, George J. Broze, Nina M. Lasky, Ryan Fiehler, Jisong Cui, David Ginsburg, Zhong Fu Huang
Publikováno v:
Proceedings of the National Academy of Sciences. 97:6734-6738
Protein Z (PZ) is a vitamin K-dependent plasma protein whose function has been uncertain. The structure of PZ is very similar to that of the coagulation-related factors VII, IX, and X and PC, but PZ differs from these other proteins in that it is not
Autor:
Zhong-Fu Huang, George J. Broze, E. Alan Mast, A. Darryl Higuchi, L. Alan Schwartz, Ilka Warshawsky
Publikováno v:
Biochemical Journal. 327:577-583
Tissue factor pathway inhibitor (TFPI) is a primary regulator of the initiation of blood coagulation. TFPI is internalized and degraded by HepG2 cells through the low-density-lipoprotein receptor-related protein (LRP) but also binds another molecule