Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Zhong‐Jian Shen"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Current treatments for Alzheimer’s disease (AD) have largely failed to yield significant therapeutic benefits. Novel approaches are desperately needed to help address this immense public health issue. Data suggests that early in
Externí odkaz:
https://doaj.org/article/b0597f4a392f486d8f35d5a7d20e8da1
Publikováno v:
Ecological Indicators, Vol 142, Iss , Pp 109187- (2022)
Blue and green spaces (BGSs) are used as the important resource to mitigate urban heat island (UHI) effect through their cooling effect. However, research on the supply and demand of cooling effect of BGSs is limited. This study used the Fujian Delta
Externí odkaz:
https://doaj.org/article/da1575440e2f4486965ac7034eac4bf3
Publikováno v:
Cells, Vol 10, Iss 2, p 211 (2021)
Eosinophils become polarized in response to cytokines such IL-5 or eotaxin prior to directional migration. Polarization is preceded by F-actin assembly, but the mechanisms that regulate these events and how the shape change influences cell migration
Externí odkaz:
https://doaj.org/article/d1f2d5ec51bd4de49c3faf34743cc262
Autor:
Zhong-Jian Shen, Yan-Jun Liu, Xu-Hui Gao, Xiao-Ming Liu, Song-Dou Zhang, Zhen Li, Qing-Wen Zhang, Xiao-Xia Liu
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Thioredoxins (Trxs), a member of the thioredoxin system, play crucial roles in maintaining intracellular redox homeostasis and protecting organisms against oxidative stress. In this study, we cloned and characterized two genes, GmTrx2 and GmTrx-like1
Externí odkaz:
https://doaj.org/article/a53c7f92360c4ac3a78f4607f99842d4
Autor:
Zhong-Jian Shen, James S. Malter
Publikováno v:
Biomolecules, Vol 5, Iss 2, Pp 412-434 (2015)
The accumulation of 3' untranslated region (3'-UTR), AU-rich element (ARE) containing mRNAs, are predominantly controlled at the post-transcriptional level. Regulation appears to rely on a variable and dynamic interaction between mRNA target and ARE-
Externí odkaz:
https://doaj.org/article/eaa6ca8dbd9e4b20808e5a3de19ed767
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
We have recently reported that, unlike IL-5 and GM-CSF, IL-3 induces increased translation of a subset of mRNAs. In addition, we have demonstrated that Pin1 controls the activity of mRNA binding proteins, leading to enhanced mRNA stability, GM-CSF pr
Externí odkaz:
https://doaj.org/article/7bd618711b9e44558ea83645e81441e2
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150093 (2016)
Tubulo-interstitial fibrosis is a common, destructive endpoint for a variety of kidney diseases. Fibrosis is well correlated with the loss of kidney function in both humans and rodents. The identification of modulators of fibrosis could provide novel
Externí odkaz:
https://doaj.org/article/b3856fd3e8d6423ab0d841700c02dc26
Autor:
Zhong-Jian Shen, Jie Hu, Aktar Ali, Johanne Pastor, Kazuhiro Shiizaki, Robert D Blank, Makoto Kuro-o, James S Malter
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63565 (2013)
Bone is constantly formed and resorbed throughout life by coordinated actions of osteoblasts and osteoclasts. However, the molecular mechanisms involved in osteoblast function remain incompletely understood. Here we show, for the first time, that the
Externí odkaz:
https://doaj.org/article/deb0b6a2ab754b8dbcdec4662cbff34e
Autor:
Stephane Esnault, Ruedi K Braun, Zhong-Jian Shen, Zhuzai Xiang, Erika Heninger, Robert B Love, Matyas Sandor, James S Malter
Publikováno v:
PLoS ONE, Vol 2, Iss 2, p e226 (2007)
BACKGROUND/ABSTRACT: Immune responses initiated by T cell receptor (TCR) and costimulatory molecule mediated signaling culminate in maximal cytokine mRNA production and stability. The transcriptional responses to co-stimulatory T cell signalling invo
Externí odkaz:
https://doaj.org/article/a98a56fa8d6644c5a701cc037416a9d1
Autor:
Zhong‐Jian Shen, Fang Zhu, Yan‐Jun Liu, Zhen Li, Timothy W. Moural, Xiao‐Ming Liu, Xiaoxia Liu
Publikováno v:
Pest Management Science. 78:3540-3550
The cotton bollworm, Helicoverpa armigera, is a worldwide polyphagous pest, causing huge economic losses in vegetable, cotton and corn crops, among others. Owing to long-term exposure to Bacillus thuringiensis (Bt) toxins, evolution of resistance has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d44c00acefc0f2ff747953f4b93e011
https://doi.org/10.1002/ps.6997
https://doi.org/10.1002/ps.6997