Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury

Autor: Jin, Yuting, Li, Changyong, Xu, Dongwei, Zhu, Jianjun, Wei, Song, Zhong, Andrew, Sheng, Mingwei, Duarte, Sergio, Coito, Ana J, Busuttil, Ronald W, Xia, Qiang, Kupiec-Weglinski, Jerzy W, Ke, Bibo

Publikováno v: Cellular & molecular immunology, vol 17, iss 12

Notch signaling plays important roles in the regulation of immune cell functioning during the inflammatory response. Activation of the innate immune signaling receptor NLRP3 promotes inflammation in injured tissue. However, it remains unknown whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::704c1fb2e2a34fa4e4ab0ba75f92807b
https://escholarship.org/uc/item/47c8z3rr

The sustainability of the UBC Food System Collaborative Project III

Autor: Chan, Ivan, Gopal, Christina, Kuo, Tony, Lorentsen, Hanne, Preston, Beverlee, Tiro, Lara, Zhong, Andrew

As part of our contribution to “The Sustainability of the UBC Food System Collaborative Project”, we have collectively examined our value assumptions to formulate a vision and define the meaning of sustainability in terms of the UBC food system.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ade6a79a1476d8db1ff7291c202e0b4

Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury.

Autor: Jin Y; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Liver Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Li C; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Physiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China., Xu D; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Liver Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Zhu J; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Department of Liver Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Wei S; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Zhong A; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Sheng M; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Duarte S; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Coito AJ; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Busuttil RW; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Xia Q; Department of Liver Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Kupiec-Weglinski JW; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Ke B; The Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. bke@mednet.ucla.edu.

Publikováno v: Cellular & molecular immunology [Cell Mol Immunol] 2020 Dec; Vol. 17 (12), pp. 1245-1256. Date of Electronic Publication: 2019 Oct 31.