Challenges and Efficacy of Astrocyte-to-Neuron Reprogramming in Spinal Cord Injury: In Vitro Insights and In Vivo Outcomes.

Autor: Niceforo A; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA.; Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA., Zholudeva LV; Gladstone Institutes, San Francisco, California, 94158, USA., Fernandes S; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA.; Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA., Lane MA; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA.; Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA., Qiang L; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA.; Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA, 19129, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 29. Date of Electronic Publication: 2024 Mar 29.

Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes.

Autor: Nishino T; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Ranade SS; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Pelonero A; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., van Soldt BJ; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Ye L; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Alexanian M; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Koback F; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Huang Y; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Sadagopan N; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA.; Division of Cardiology, Department of Medicine, University of California, San Francisco; San Francisco, CA, USA., Lam A; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Zholudeva LV; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Li F; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Padmanabhan A; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA.; Division of Cardiology, Department of Medicine, University of California, San Francisco; San Francisco, CA, USA., Thomas R; Gladstone Institutes; San Francisco, CA, USA., van Bemmel JG; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Gifford CA; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Costa MW; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA., Srivastava D; Gladstone Institutes; San Francisco, CA, USA.; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone; San Francisco, CA, USA.; Division of Cardiology, Department of Pediatrics, University of California, San Francisco; San Francisco, CA, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco; San Francisco, CA, USA.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2023 Dec; Vol. 2 (12), pp. 1190-1203. Date of Electronic Publication: 2023 Nov 30.

Diseased, differentiated and difficult: Strategies for improved engineering of in vitro neurological systems.

Autor: Elder N; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, United States.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, United States.; Gladstone Institutes, San Francisco, CA, United States., Fattahi F; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, United States.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, United States., McDevitt TC; Gladstone Institutes, San Francisco, CA, United States.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States.; Sana Biotechnology, Inc., South San Francisco, CA, United States., Zholudeva LV; Gladstone Institutes, San Francisco, CA, United States.

Publikováno v: Frontiers in cellular neuroscience [Front Cell Neurosci] 2022 Sep 27; Vol. 16, pp. 962103. Date of Electronic Publication: 2022 Sep 27 (Print Publication: 2022).

Transneuronal tracing to map connectivity in injured and transplanted spinal networks.

Autor: Fortino TA; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America; The Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America., Randelman ML; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America; The Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America., Hall AA; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America; The Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America., Singh J; Department of Molecular Genetics & Microbiology, College of Medicine, University of Florida, Gainesville, FL 32608, United States of America., Bloom DC; Department of Molecular Genetics & Microbiology, College of Medicine, University of Florida, Gainesville, FL 32608, United States of America., Engel E; Neuroscience Institute & Viral Core, Princeton University, Princeton, NJ, 08544, United States of America., Hoh DJ; Department of Neurosurgery, College of Medicine, University of Florida, Gainesville, FL, 32608, United States of America., Hou S; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America; The Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America., Zholudeva LV; Gladstone Institutes, San Francisco, CA, United States of America., Lane MA; Department of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America; The Marion Murray Spinal Cord Research Center, College of Medicine, Drexel University, Philadelphia, PA 19129, United States of America. Electronic address: mlane.neuro@gmail.com.

Publikováno v: Experimental neurology [Exp Neurol] 2022 May; Vol. 351, pp. 113990. Date of Electronic Publication: 2022 Jan 25.

Cell transplantation to repair the injured spinal cord.

Autor: Hall A; Drexel University, Philadelphia, PA, United States; Marion Murray Spinal Cord Research Center, Drexel University, Philadelphia, PA, United States., Fortino T; Drexel University, Philadelphia, PA, United States; Marion Murray Spinal Cord Research Center, Drexel University, Philadelphia, PA, United States., Spruance V; Drexel University, Philadelphia, PA, United States; Marion Murray Spinal Cord Research Center, Drexel University, Philadelphia, PA, United States; Division of Kidney, Urologic, & Hematologic Diseases, National Institutes of Health, Bethesda, MD, United States., Niceforo A; Drexel University, Philadelphia, PA, United States; Marion Murray Spinal Cord Research Center, Drexel University, Philadelphia, PA, United States., Harrop JS; Department of Neurological and Orthopedic Surgery, Thomas Jefferson University, Philadelphia, PA, United States., Phelps PE; Department of Integrative Biology & Physiology, UCLA, Los Angeles, CA, United States., Priest CA; Neurona Therapeutics, South San Francisco, CA, United States., Zholudeva LV; Drexel University, Philadelphia, PA, United States; Marion Murray Spinal Cord Research Center, Drexel University, Philadelphia, PA, United States; Gladstone Institutes, San Francisco, CA, United States., Lane MA; Drexel University, Philadelphia, PA, United States; Marion Murray Spinal Cord Research Center, Drexel University, Philadelphia, PA, United States. Electronic address: mlane.neuro@gmail.com.

Publikováno v: International review of neurobiology [Int Rev Neurobiol] 2022; Vol. 166, pp. 79-158. Date of Electronic Publication: 2022 Nov 09.