Zobrazeno 1 - 10
of 416
pro vyhledávání: '"Zhmurov A"'
Autor:
Hesam Ghafouri Kalajahi, AmirHossein Yari, Mohammad Amini, Tunc Catal, Mahya Ahmadpour Youshanlui, Omid Pourbagherian, Cigdem Sezer Zhmurov, Ahad Mokhtarzadeh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Gastric cancer (GC) is a leading cause of mortality for many people. Cancer’s initiating factors are poorly understood. miR-21 has a crucial function in several malignancies, particularly GC. Furthermore, it has been shown that miR-21 is c
Externí odkaz:
https://doaj.org/article/43dcf257af2c42209f718bd9f5887ad0
Autor:
Páll, Szilárd, Zhmurov, Artem, Bauer, Paul, Abraham, Mark, Lundborg, Magnus, Gray, Alan, Hess, Berk, Lindahl, Erik
The introduction of accelerator devices such as graphics processing units (GPUs) has had profound impact on molecular dynamics simulations and has enabled order-of-magnitude performance advances using commodity hardware. To fully reap these benefits,
Externí odkaz:
http://arxiv.org/abs/2006.09167
Autor:
Adamchik, Maria, Bubyrev, Andrey, Zhukovsky, Daniil, Zhmurov, Petr, Bunev, Alexander, Krasavin, Mikhail
Publikováno v:
In Mendeleev Communications January-February 2023 33(1):67-69
Autor:
Tatiana Sharonova, Petr Zhmurov, Stanislav Kalinin, Alessio Nocentini, Andrea Angeli, Marta Ferraroni, Mikhail Korsakov, Claudiu T. Supuran, Mikhail Krasavin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 857-865 (2022)
A series of sulfamide fragments has been synthesised and investigated for human carbonic anhydrase inhibition. One of the fragments showing greater selectivity for cancer-related isoforms hCA IX and XII was co-crystalized with hCA II showing signific
Externí odkaz:
https://doaj.org/article/2a3dc5eb7f254984b17701835310cb94
Autor:
Asquith, Nathan L., Duval, Cédric, Zhmurov, Artem, Baker, Stephen R., McPherson, Helen R., Domingues, Marco M., Connell, Simon D.A., Barsegov, Valeri, Ariëns, Robert A.S. *
Publikováno v:
In Blood Advances 12 July 2022 6(13):4015-4027
Autor:
Litvinov, Rustem I., Kononova, Olga, Maksudov, Farkhad, Zhmurov, Artem, Marx, Kenneth A., Weisel, John W., Barsegov, Valeri
The lifetimes of non-covalent A:a knob-hole bonds in fibrin probed with the optical trap-based force-clamp first increases ("catch bonds") and then decreases ("slip bonds") with increasing tensile force. Molecular modeling of "catch-to-slip" transiti
Externí odkaz:
http://arxiv.org/abs/1709.05727
We carried out dynamic force manipulations $in$ $silico$ on a variety of superhelical protein fragments from myosin, chemotaxis receptor, vimentin, fibrin, and phenylalanine zippers that vary in size and topology of their $\alpha$-helical packing. Wh
Externí odkaz:
http://arxiv.org/abs/1703.02922
Autor:
Kliuchnikov, Evgenii, Klyshko, Eugene, Kelly, Maria S., Zhmurov, Artem, Dima, Ruxandra I., Marx, Kenneth A., Barsegov, Valeri
Publikováno v:
In Computational and Structural Biotechnology Journal 2022 20:953-974
Autor:
Evgenii Kliuchnikov, Eugene Klyshko, Maria S. Kelly, Artem Zhmurov, Ruxandra I. Dima, Kenneth A. Marx, Valeri Barsegov
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 953-974 (2022)
Microtubules (MTs), a cellular structure element, exhibit dynamic instability and can switch stochastically from growth to shortening; but the factors that trigger these processes at the molecular level are not understood. We developed a 3D Microtubu
Externí odkaz:
https://doaj.org/article/7559ac355a154cb78436a62351f9e059
Autor:
Kononova, Olga, Litvinov, Rustem I., Zhmurov, Artem, Alekseenko, Andrey, Cheng, Chai-Ho, Agarwal, Silvi, Marx, Kenneth A., Weisel, John W., Barsegov, Valeri
Publikováno v:
J. Biol. Chem. 2013 288(31): 22681-22692
Polymerization of fibrin, the primary structural protein of blood clots and thrombi, occurs through binding of knobs 'A' and 'B' in the central nodule of fibrin monomer to complementary holes 'a' and 'b' in the beta- and gamma-nodules, respectively,
Externí odkaz:
http://arxiv.org/abs/1501.07898