Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Zhizhong Z Pan"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Brain circuits between medial prefrontal cortex (mPFC) and amygdala have been implicated in cortical control of emotion, especially anxiety. Studies in recent years focus on differential roles of subregions of mPFC and amygdala, and reciprocal pathwa
Externí odkaz:
https://doaj.org/article/23a34a0d62c143869fa8e0256fd62ab6
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The amygdala is a critical brain site for regulation of emotion-associated behaviors such as pain and anxiety. Recent studies suggest that differential cell types and synaptic circuits within the amygdala complex mediate interacting and opposing effe
Externí odkaz:
https://doaj.org/article/bc424242c61a4db493d9245d066da994
Autor:
Li Lu, Anantha Marisetty, Bin Liu, Mohamed Mostafa Kamal, Joy Gumin, Bethany Veo, YouQing Cai, Dina Hamada Kassem, Connie Weng, Mark E. Maynard, Kimberly N. Hood, Gregory N. Fuller, Zhizhong Z. Pan, Matthew D. Cykowski, Pramod K. Dash, Sadhan Majumder
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/df9490dd876447009a34d32ef21ffdea
Autor:
Xia Zhu, Wenjie Zhou, Yan Jin, Haodi Tang, Peng Cao, Yu Mao, Wen Xie, Xulai Zhang, Fei Zhao, Min-Hua Luo, Haitao Wang, Jie Li, Wenjuan Tao, Zahra Farzinpour, Likui Wang, Xiangyao Li, Juan Li, Zheng-Quan Tang, Chenghua Zhou, Zhizhong Z. Pan, Zhi Zhang
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 3847-3858.e5 (2019)
Summary: While comorbid pain in depression (CP) occurs at a high rate worldwide, the neural connections underlying the core symptoms of CP have yet to be elucidated. Here, we define a pathway whereby GABAergic neurons from the central nucleus of the
Externí odkaz:
https://doaj.org/article/5f9f878ca3db4dffaa101a89047f694f
Publikováno v:
J Neurosci
Emotional disorders are common comorbid conditions that further exacerbate the severity and chronicity of chronic pain. However, individuals show considerable vulnerability to the development of chronic pain under similar pain conditions. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308ae25bafc67ffde40bb9539c908d75
https://doi.org/10.1523/jneurosci.1259-19.2020
https://doi.org/10.1523/jneurosci.1259-19.2020
Publikováno v:
Neuroscience
Increasing evidence suggests that long-term opioids and pain induce similar adaptive changes in the brain’s reward circuits, however, how pain alters the addictive properties of opioids remains poorly understood. In this study using a rat model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b632c98542365ce9768065539515a1
https://pubmed.ncbi.nlm.nih.gov/31863796
https://pubmed.ncbi.nlm.nih.gov/31863796
Recent years have seen a surging number of epigenetic studies and rapid progress in understanding of epigenetic mechanisms of gene regulation and their dysfunctions in the pathogenesis of neurological diseases such as chronic pain. As we gain increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a315030d984c6e0cd492b3c1d9915a40
https://doi.org/10.1016/b978-0-12-814070-3.00006-5
https://doi.org/10.1016/b978-0-12-814070-3.00006-5
Autor:
Jie Li, Likui Wang, Yan Jin, Juan Li, Changmao Chen, Wenjie Zhou, Chenghua Zhou, Yu Mao, Zhen Quan Tang, Zhizhong Z. Pan, Haitao Wang, Xulai Zhang, Wen Xie, Zhi Zhang, Wenjuan Tao, Xiang-Yao Li, Yuping Wang
Publikováno v:
Progress in neurobiology
Pain symptoms can be transmitted across generations, but the mechanisms underlying these outcomes remain poorly understood. Here, we identified an essential role for primary somatosensory cortical (S1) glutamate neuronal DNA methyl-CpG binding protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd905274710fdb6cafc3f3a3ac6ce92
https://doi.org/10.1016/j.pneurobio.2020.101790
https://doi.org/10.1016/j.pneurobio.2020.101790
Publikováno v:
Molecular Pain
The amygdala is important in regulation of emotion-associated behavioral responses both to positive reinforcing stimuli such as addicting opioids and to negative aversive stimuli such as fear and pain. Glutamatergic neurotransmission in amygdala play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3c5c2e512421635c0e334e812702d1
https://doi.org/10.1177/1744806920911543
https://doi.org/10.1177/1744806920911543
Autor:
Mohamed M. Kamal, Zhizhong Z. Pan, Bethany Veo, Joy Gumin, Mark E. Maynard, Dina H. Kassem, Anantha Marisetty, You Qing Cai, Matthew D. Cykowski, Pramod K. Dash, Gregory N. Fuller, Li Lu, Connie C. Weng, Kimberly N. Hood, Bin Liu, Sadhan Majumder
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Overexpression of REST has been implicated in brain tumors, ischemic insults, epilepsy, and movement disorders such as Huntington’s disease. However, owing to the lack of a conditional REST overexpression animal model, the mechanism of action of RE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e835199777170be1a4afdf43626e27f
http://europepmc.org/articles/PMC6092433
http://europepmc.org/articles/PMC6092433