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pro vyhledávání: '"Zhizhan Song"'
Autor:
Linghong Huang, Helene Bon, Mabrouka Maamra, Toby Holmes, John Atkinson, Katharine Cain, Jeff Kennedy, Catherine Kettleborough, David Matthews, Breda Twomey, Jia Ni, Zhizhan Song, Philip F Watson, Timothy S Johnson
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0298864 (2024)
Fibrotic remodeling is the primary driver of functional loss in chronic kidney disease, with no specific anti-fibrotic agent available for clinical use. Transglutaminase 2 (TG2), a wound response enzyme that irreversibly crosslinks extracellular matr
Externí odkaz:
https://doaj.org/article/7737e1a42d454e9d95b052f6ac871f2f
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 4, Pp 359-368 (2021)
Abstract Background Chronic kidney disease (CKD) has a high global prevalence and large unmet need. Central to developing new CKD therapies are in vivo models in CKD. However, next‐generation antibody, protein, and gene therapies are highly specifi
Externí odkaz:
https://doaj.org/article/f98b715ba6764f599a030c958404b705
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 4, Pp 359-368 (2021)
Animal Models and Experimental Medicine
Animal Models and Experimental Medicine
Background Chronic kidney disease (CKD) has a high global prevalence and large unmet need. Central to developing new CKD therapies are in vivo models in CKD. However, next‐generation antibody, protein, and gene therapies are highly specific, meanin