Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zhiyun Jin"'
Autor:
Ayat Zagzoog, Asher L. Brandt, Tallan Black, Eunhyun D. Kim, Riley Burkart, Mikin Patel, Zhiyun Jin, Maria Nikolaeva, Robert B. Laprairie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The first synthetic cannabinoid receptor agonists (SCRAs) were designed as tool compounds to study the endocannabinoid system’s two predominant cannabinoid receptors, CB1R and CB2R. Unfortunately, novel SCRAs now represent the most rapidly
Externí odkaz:
https://doaj.org/article/b6aa1fa4ea2b4839a0bdba526e98a3e7
Publikováno v:
International Review of Economics & Finance. 84:262-273
Publikováno v:
SSRN Electronic Journal.
Autor:
Tallan Black, Robert B. Laprairie, Asher L. Brandt, Zhiyun Jin, Maria Nikolaeva, Riley Burkart, Ayat Zagzoog, Mikin Patel, Eunhyun D. Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports
Scientific Reports
The first synthetic cannabinoid receptor agonists (SCRAs) were designed as tool compounds to study the endocannabinoid system’s two predominant cannabinoid receptors, CB1R and CB2R. Unfortunately, novel SCRAs now represent the most rapidly prolifer
Publikováno v:
Journal of Water Supply: Research and Technology - Aqua. 66:621-631
The aim of this study was to evaluate if chlorate, chlorite, perchlorate and bromate ions are found in treated water from 16 Canadian drinking water treatment plants (WTPs) that use hypochlorite as a disinfectant. The WTPs in this survey had unusuall
Publikováno v:
Harmful Algae. 42:34-42
Cyanobacteria blooms may present a public health concern in sources of drinking water and recreational water due to the production of toxins by some species, microcystins being the most commonly found. It is possible to detect microcystins using inst
Autor:
Annie Barsalou, Normand Beaulieu, Marja Dubay, Naomy Bernstein, Jeff Gillespie, Marie-France Robert, Jubrail Rahil, Isabelle Dupont, Ian Chute, Sylvain Lefebvre, Marie-Claude Granger, Hannah Nguyen, Oscar Mario Saavedra, James Wang, Jeffrey M. Besterman, Serge Gravel, Amal Wahhab, Lijie Zhan, Arkadii Vaisburg, Roussen Pascal, Carole Beaulieu, Zhiyun Jin, Franck Raeppel, Robert Deziel, David B. Llewellyn, A. Robert MacLeod, Stephen William Claridge
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2793-2798
A series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases is described. The compounds demonstrated potency with IC50 values in the low nanomolar range in vitro while the lead compound also showed in vivo activity against
Autor:
Giliane Bouchain, James Wang, Jeffrey M. Besterman, Marielle Fournel, Pu Theresa Yan, J Yuk, Oscar Moradei, Frédéric Gaudette, Marie-Claude Trachy-Bourget, Jubrail Rahil, Marie-France Robert, Aihua Lu, Zuomei Li, Naomy Bernstein, Stephane Raeppel, Zhiyun Jin, Isabelle Paquin, Jeff Gillespie, Daniel Delorme, Sylvie Frechette, Soon Hyung Woo, Arkadii Vaisburg, Nancy Z. Zhou, Silvana Leit, A. Robert MacLeod
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6729-6733
A variety of N-(2-amino-phenyl)-4-(heteroarylmethyl)-benzamides were designed and synthesized. These compounds were shown to inhibit recombinant human HDAC1 with IC(50) values in the sub-micromolar range. In human cancer cells growing in culture thes
Publikováno v:
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 28(3)
A new method for the determination of perchlorate in water and soil samples using on-line enrichment in a capillary zone electrophoresis–mass spectrometry is presented. The target analytes in the sample solutions were introduced into the capillary
Autor:
Marielle Fournel, Pu T. Yan, Jeffrey M. Besterman, Ann Kalita, Zhiyun Jin, Jubrail Rahil, Marie-Claude Trachy-Bourget, Isabelle Paquin, Frédéric Gaudette, Stephane Raeppel, Silvana Leit, Giliane Bouchain, Jeff Gillespie, Zuomei Li, Daniel Delorme, Arkadii Vaisburg, A. Robert MacLeod, Naomy Bernstein, Sylvie Frechette, Aihua Lu, Nancy Z. Zhou, Oscar Moradei, James Wang
Publikováno v:
Journal of medicinal chemistry. 51(14)
The design, synthesis, and biological evaluation of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide 8 (MGCD0103) is described. Compound 8 is an isotype-selective small molecule histone deacetylase (HDAC) inhibitor that select