Zobrazeno 1 - 10
of 539
pro vyhledávání: '"Zhiyong Liang"'
Publikováno v:
Journal of Pancreatology, Vol 7, Iss 2, Pp 131-140 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors and is characterized by dense desmoplasia and immune desert. Regulatory T cells (Tregs) are critical components of the immune tumor microenvironment (TIME) of PDAC. Treg-i
Externí odkaz:
https://doaj.org/article/f3d1e11d034943fcb50cfbab186b60e6
Autor:
Yike Gao, Boju Pan, Hongbao Jia, Yang Zhang, Shu Wang, Yuming Wang, Sumei Zhang, Mei Li, Anqi Wang, Xiaoxi Wang, Kun Zhao, Zixin Zhang, Jian Sun, Dan Guo, Zhiyong Liang
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Ovarian clear cell carcinoma (OCCC), well known for its chemoresistance to platinum-based chemotherapy, exhibited a good response in clinical trials of anti–PD-1/PD-L1 inhibitors. By assessing PD-L1 expression, we sought to dete
Externí odkaz:
https://doaj.org/article/ca93f2ce8c944daab49318dab2fafd7f
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: The C-X-C motif chemokine ligand 9 (CXCL9) plays a pivotal role in tumor immunity by recruiting and activating immune cells. However, the relationship between CXCL9 expression and prognosis in triple-negative breast cancer (TNBC) is uncle
Externí odkaz:
https://doaj.org/article/d7c3f3e66c7246ce8029b85e863d0d41
Autor:
Sumei Zhang, Yike Gao, Pan Wang, Shu Wang, Yuming Wang, Mei Li, Anqi Wang, Kun Zhao, Zixin Zhang, Jian Sun, Dan Guo, Zhiyong Liang
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 21996-22005 (2023)
Abstract Aim As the second most prevalent subtype of epithelial ovarian cancers, ovarian clear cell carcinoma (OCCC) is known for its chemoresistance to conventional platinum‐based therapy. In this work, we examined the tryptophan (Trp) metabolism
Externí odkaz:
https://doaj.org/article/d61beee2d1e04c3096ad73ccebec3c7c
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Mesenchymal epithelial transition (MET) factor alteration in non-small cell lung cancer (NSCLC) includes MET exon 14 skipping alteration (METex14 skipping), MET gene amplification, MET gene mutation (mainly kinase domain mutation), MET gene fusion, a
Externí odkaz:
https://doaj.org/article/10d94d3f0c524e828debe257f2172ccd
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundThe significance of neuroendocrine (NE) markers in triple-negative breast cancer (TNBC) patients has not been investigated. This study aims to clarify the incidence and prognostic significance of NE marker expression in TNBC, determine its
Externí odkaz:
https://doaj.org/article/ff906ca641cf4ad0aed83efa5e90ce4d
Autor:
Dan Guo, Sumei Zhang, Yike Gao, Jinghua Shi, Xiaoxi Wang, Zixin Zhang, Yaran Zhang, Yuming Wang, Kun Zhao, Mei Li, Anqi Wang, Pan Wang, Yanqin Gou, Miao Zhang, Meiyu Liu, Yuhan Zhang, Rui Chen, Jian Sun, Shu Wang, Xunyao Wu, Zhiyong Liang, Jie Chen, Jinghe Lang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The two most prevalent subtypes of epithelial ovarian carcinoma (EOC) are ovarian clear cell carcinoma (OCCC) and high-grade serous ovarian carcinoma (HGSC). Patients with OCCC have a poor prognosis than those with HGSC due to chemoresistanc
Externí odkaz:
https://doaj.org/article/b7e7079dca0242208830951fedf89c1c
Autor:
Lei Li, Yu Gu, Mengpei Zhang, Xiaohua Shi, Zhe Li, Xinyun Xu, Tianqi Sun, Yu Dong, Chao Xue, Xiaoru Zhu, Ran Lv, Kai Jiao, Xuwo Ji, Li-juan Wang, Yang Zhang, Zhiyong Liang, Ying Jin, Rutie Yin, Ming Wu, Han Liang
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Homologous recombination deficiency (HRD) testing has been approved by FDA for selecting epithelial ovarian cancer (EOC) patients who may benefit from the first-line poly (ADP-ribose) polymerase inhibitor (PARPi) maintenance therapy. However
Externí odkaz:
https://doaj.org/article/68573d2da80e4640b5dc7c1cebdf41b8
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Cuproptosis is recently emerging as a hot spot in cancer research. However, its role in pancreatic adenocarcinoma (PAAD) has not yet been clarified. This study aimed to explore the prognostic and therapeutic implications of cuprop
Externí odkaz:
https://doaj.org/article/e4a13a4d162449cc84bdbfd9815412da
Autor:
Xiaoliang Lan, Xiaoxiao Wu, Chao Zhang, Genxia Wei, Bingbing Li, Weihao Qiu, Danyi Li, Huanwen Wu, Yanqing Ding, Jie Yuan, Zaixian Tai, Zuoquan Yang, Zhiyong Liang, Dan Su, Li Liang
Publikováno v:
Journal of Bio-X Research, Vol 5, Iss 4, Pp 171-180 (2022)
Objective:. The genomic landscapes of metastatic colorectal cancer (mCRC) have been extensively studied; however, the genetic mechanisms underlying the locoregional recurrence (LR) of CRC remain unclear. The objective of our study was to investigate
Externí odkaz:
https://doaj.org/article/bc8dc46bd9504bbc8b3af045fed5e9bb