Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Zhiyin Song"'
Autor:
Jun Dong, Li Chen, Fei Ye, Junhui Tang, Bing Liu, Jiacheng Lin, Pang-Hu Zhou, Bin Lu, Min Wu, Jia-Hong Lu, Jing-Jing He, Simone Engelender, Qingtao Meng, Zhiyin Song, He He
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Endoplasmic reticulum (ER)-mitochondria contacts are critical for the regulation of lipid transport, synthesis, and metabolism. However, the molecular mechanism and physiological function of endoplasmic reticulum-mitochondrial contacts remai
Externí odkaz:
https://doaj.org/article/9ce0791913fe4ff9aa6525cb89bbb6a4
Autor:
Tianshu Hao, Jianglong Yu, Zhida Wu, Jie Jiang, Longlong Gong, Bingjun Wang, Hanze Guo, Huabin Zhao, Bin Lu, Simone Engelender, He He, Zhiyin Song
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Mitochondria are the key organelles for sensing oxygen, which is consumed by oxidative phosphorylation to generate ATP. Lysosomes contain hydrolytic enzymes that degrade misfolded proteins and damaged organelles to maintain cellular homeosta
Externí odkaz:
https://doaj.org/article/21df65c007b74e62808b5795885d6a13
Autor:
Yu Dong, Xu-Xu Zhuang, Yi-Ting Wang, Jieqiong Tan, Du Feng, Min Li, Qing Zhong, Zhiyin Song, Han-Ming Shen, Evandro F. Fang, Jia-Hong Lu
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106835- (2023)
Maintaining mitochondrial homeostasis is a potential therapeutic strategy for various diseases, including neurodegenerative diseases, cardiovascular diseases, metabolic disorders, and cancer. Selective degradation of mitochondria by autophagy (mitoph
Externí odkaz:
https://doaj.org/article/338ba7d674e94ef8af43ffb97b28cd88
Autor:
Yujie Li, Dawei Huang, Lianqun Jia, Fugen Shangguan, Shiwei Gong, Linhua Lan, Zhiyin Song, Juan Xu, Chaojun Yan, Tongke Chen, Yin Tan, Yongzhang Liu, Xingxu Huang, Carolyn K. Suzuki, Zhongzhou Yang, Guanlin Yang, Bin Lu
Publikováno v:
Research, Vol 6 (2023)
Interorganelle contacts and communications are increasingly recognized to play a vital role in cellular function and homeostasis. In particular, the mitochondria–endoplasmic reticulum (ER) membrane contact site (MAM) is known to regulate ion and li
Externí odkaz:
https://doaj.org/article/685beb4752a3456b9a45618c253a4478
Autor:
Yingying Shi, You Wang, Huangang Jiang, Xuehua Sun, Hui Xu, Xue Wei, Yan Wei, Guohui Xiao, Zhiyin Song, Fuxiang Zhou
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-13 (2021)
Abstract Mitochondrial retrograde signaling (mito-RTG) triggered by mitochondrial dysfunction plays a potential role in regulating tumor metabolic reprogramming and cellular sensitivity to radiation. Our previous studies showed phos-pyruvate dehydrog
Externí odkaz:
https://doaj.org/article/746d798051e94efb8bcfa92632dcd21c
Autor:
Liang Yang, Haite Tang, Xiaobing Lin, Yi Wu, Sheng Zeng, Yongzhang Pan, Yukun Li, Ge Xiang, Yi-Fang Lin, Shi-Mei Zhuang, Zhiyin Song, Yiguo Jiang, Xingguo Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Optic Atrophy 1 (OPA1) has well-established roles in both mitochondrial fusion and apoptotic crista remodeling and is required for the maintenance and distribution of mitochondrial DNA (mtDNA), which are essential for energy metabolism. However, the
Externí odkaz:
https://doaj.org/article/0d7372cd69674f4eba43e0a7c2063873
Publikováno v:
Cells, Vol 8, Iss 4, p 379 (2019)
Mitochondrion harbors its own DNA (mtDNA), which encodes many critical proteins for the assembly and activity of mitochondrial respiratory complexes. mtDNA is packed by many proteins to form a nucleoid that uniformly distributes within the mitochondr
Externí odkaz:
https://doaj.org/article/6c417b6e17b842259b5299d2c82f8dcb
Publikováno v:
Mitochondrial Communications. 1:2-12
Autor:
Fatimah Abd Elghani, Hazem Safory, Haya Hamza, Mor Savyon, Malik Farhoud, Michal Toren‐Hershoviz, Zagorka Vitic, Kirsten Ebanks, Vered Shani, Sleman Bisharat, Lihi Shaulov, Claude Brodski, Zhiyin Song, Rina Bandopadhyay, Simone Engelender
Publikováno v:
Aging cell. 21(12)
Parkinson's disease (PD) is characterized by degeneration of neurons, particularly dopaminergic neurons in the substantia nigra. PD brains show accumulation of α-synuclein in Lewy bodies and accumulation of dysfunctional mitochondria. However, the m
Publikováno v:
Hepatology. 76