Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Zhixiong Dong"'
Autor:
Zhihai Zheng, Youjuan Zhao, Hongjia Yu, Tingting Wang, Jinhai Li, Liang Xu, Chunming Ding, Lan He, Lijun Wu, Zhixiong Dong
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Mitochondrial transcription termination factor 3 (MTERF3) negatively regulates mitochondrial DNA transcription. However, its role in hepatocellular carcinoma (HCC) progression remains elusive. Here, we investigate the expression and function
Externí odkaz:
https://doaj.org/article/0da64d4cd60a4b01b799d675772cdd3a
Autor:
Shuanghui Liu, Fanggui Shao, Yourong Wang, Yurui Zhang, Hongjia Yu, Ningxin Zhang, Lan He, Qingran Kong, Hao Jiang, Zhixiong Dong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Copy number variations (CNVs) play a vital role in regulating genes expression and tumorigenesis. We explored the copy number alterations in early-stage lung adenocarcinoma using high-throughput sequencing and nucleic acid flight mass spectr
Externí odkaz:
https://doaj.org/article/db50300ee44c49279b58c5722e126dc4
Autor:
Zhengzheng Zhang, Wenran Xie, Bojiang Gong, Xue Liang, Hongjia Yu, Yanwen Yu, Zhixiong Dong, Fanggui Shao
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Small GTPases regulate multiple important cellular behaviors and their activities are strictly controlled by a mass of regulators. The dysfunction or abnormal expression of small GTPases or their regulators was frequently observed in various
Externí odkaz:
https://doaj.org/article/74f8d54b76714edc8a87bf691a78b802
Autor:
Zhixiong Dong, Jinhai Li, Wenqing Dai, Dongbo Yu, Youjuan Zhao, Shuanghui Liu, Xuanwen Li, Zhengzheng Zhang, Rui Zhang, Xue Liang, Qingran Kong, Shengnan Jin, Hao Jiang, Wei Jiang, Chunming Ding
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-15 (2023)
Abstract Ribosome biogenesis (RiBi) plays a pivotal role in carcinogenesis by regulating protein translation and stress response. Here, we find that RRP15, a nucleolar protein critical for RiBi and checkpoint control, is frequently upregulated in pri
Externí odkaz:
https://doaj.org/article/42528bb3297e49eda7cc8158268d8da6
Autor:
Jingyu Li, Jiaming Zhang, Weibo Hou, Xu Yang, Xiaoyu Liu, Yan Zhang, Meiling Gao, Ming Zong, Zhixiong Dong, Zhonghua Liu, Jingling Shen, Weitao Cong, Chunming Ding, Shaorong Gao, Guoning Huang, Qingran Kong
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-20 (2022)
Abstract Metabolism feeds into the regulation of epigenetics via metabolic enzymes and metabolites. However, metabolic features, and their impact on epigenetic remodeling during mammalian pre-implantation development, remain poorly understood. In thi
Externí odkaz:
https://doaj.org/article/11fef895715b4d9787d474fd00f7006b
Autor:
Weibo Hou, Ming Zong, Qi Zhao, Xu Yang, Jiaming Zhang, Shuanghui Liu, Xuanwen Li, Lijun Chen, Chun Tang, Xinyu Wang, Zhixiong Dong, Meiling Gao, Jianzhong Su, Qingran Kong
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107469- (2023)
Summary: Long non-coding RNAs (lncRNAs) have been implicated in diverse biological processes. However, the functional mechanisms have not yet been fully explored. Characterizing the interactions of lncRNAs with chromatin is central to determining the
Externí odkaz:
https://doaj.org/article/58c1e2f280dc4293930e45a4943667a5
Autor:
Changrui Qian, Zewei Jiang, Tong Zhou, Tao Wu, Yi Zhang, Ju Huang, Jinglin Ouyang, Zhixiong Dong, Guang Wu, Jiawei Cao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundGlobally, lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths. It is a progressive disorder that arises from multiple genetic and environmental factors. Dysregulated expression of vesicle-mediated transport-related gene
Externí odkaz:
https://doaj.org/article/c22e2488bc4b41c786cb9c9d4cfe8cff
Autor:
Zhiwei Liu, Guoling Ren, Chenyan Shangguan, Lijing Guo, Zhixiong Dong, Yueyang Li, Weina Zhang, Li Zhao, Pingfu Hou, Yu Zhang, Xiuli Wang, Jun Lu, Baiqu Huang
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40943 (2012)
All-trans retinoic acid (ATRA) has been widely investigated for treatments of many cancers including prostate cancer. HOXB13, silenced in androgen receptor-negative (AR(-)) prostate cancer cells, plays a role in AR(-) prostate cancer cell growth arre
Externí odkaz:
https://doaj.org/article/2108206c76da497699d7905561fda4b1
Autor:
Chenfei Kong, Changqing Wang, Liping Wang, Musong Ma, Chunbo Niu, Xiaoqian Sun, Juan Du, Zhixiong Dong, Shan Zhu, Jun Lu, Baiqu Huang
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22666 (2011)
Epithelial to mesenchymal transition (EMT) plays an important role in many biological processes. The latest studies revealed that aggressive breast cancer, especially the triple-negative breast cancer (TNBC) subtype was frequently associated with app
Externí odkaz:
https://doaj.org/article/d3b244dd1cdb4531bba1866b4de4093f
Autor:
Jiang Tan, Jun Lu, Wei Huang, Zhixiong Dong, Chenfei Kong, Lin Li, Lina Gao, Jianhua Guo, Baiqu Huang
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6792 (2009)
Mesenchymal stem cells (MSCs) possess self-renewal and multi-lineage differentiation potentials. It has been established that epigenetic mechanisms such as histone modifications could be critical for determining the fate of stem cells. In this study,
Externí odkaz:
https://doaj.org/article/f3284470495a4355aa947148264b81c3