Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat‐shock protein family

Autor: Bin Wang, Mengru Pang, Yancheng Song, Haixing Wang, Pan Qi, Shanshan Bai, Xiaoxuan Lei, Shikun Wei, Zhixian Zong, Sien Lin, Xiaoting Zhang, Xiaotong Cen, Xia Wang, Yongkang Yang, Yuan Li, Yan Wang, Hongjie Xu, Lin Huang, Micky Tortorella, Biao Cheng, Yukwai Lee, Dajiang Qin, Gang Li

Publikováno v: Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)

Abstract The high mortality rate of patients with diabetic foot ulcers is urging the appearance of an effective biomedical drug. Senescence is one of the major reasons of aging‐induced decline in the diabetic wound. Our previous studies have demons

Externí odkaz: https://doaj.org/article/85a2e4d709184f659ddeb42b68003c2e

Rejuvenated ageing mesenchymal stem cells by stepwise preconditioning ameliorates surgery-induced osteoarthritis in rabbits

Autor: Zhixian Zong, Xiaoting Zhang, Zhengmeng Yang, Weihao Yuan, Jianping Huang, Weiping Lin, Ting Chen, Jiahao Yu, Jiming Chen, Liao Cui, Gang Li, Bo Wei, Sien Lin

Publikováno v: Bone & Joint Research, Vol 10, Iss 1, Pp 10-21 (2020)

Aims: Ageing-related incompetence becomes a major hurdle for the clinical translation of adult stem cells in the treatment of osteoarthritis (OA). This study aims to investigate the effect of stepwise preconditioning on cellular behaviours in human m

Externí odkaz: https://doaj.org/article/0f83a4f99fba442da7b32ef2853a1f37

Recent Advances in Pharmacological Intervention of Osteoarthritis: A Biological Aspect

Autor: Jinxia Deng, Zhixian Zong, Zhanpeng Su, Haicong Chen, Jianping Huang, Yanru Niu, Huan Zhong, Bo Wei

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Osteoarthritis (OA) is a degenerative joint disease in the musculoskeletal system with a relatively high incidence and disability rate in the elderly. It is characterized by the degradation of articular cartilage, inflammation of the synovial membran

Externí odkaz: https://doaj.org/article/b0988ae9a17848398b9950d4be0b511a

Hydrothermally treated coral scaffold promotes proliferation of mesenchymal stem cells and enhances segmental bone defect healing.

Autor: Jianping Huang, Jaehan Park, Narae Jung, Hong Seok Moon, Zhixian Zong, Gang Li, Sien Lin, Sung-Won Cho, Youngbum Park

Publikováno v: Frontiers in Bioengineering & Biotechnology; 2024, p1-10, 10p

Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat‐shock protein family

Autor: Bin Wang, Mengru Pang, Yancheng Song, Haixing Wang, Pan Qi, Shanshan Bai, Xiaoxuan Lei, Shikun Wei, Zhixian Zong, Sien Lin, Xiaoting Zhang, Xiaotong Cen, Xia Wang, Yongkang Yang, Yuan Li, Yan Wang, Hongjie Xu, Lin Huang, Micky Tortorella, Biao Cheng, Yukwai Lee, Dajiang Qin, Gang Li

Publikováno v: Wang, B, Pang, M, Song, Y, Wang, H, Qi, P, Bai, S, Lei, X, Wei, S, Zong, Z, Lin, S, Zhang, X, Cen, X, Wang, X, Yang, Y, Li, Y, Wang, Y, Xu, H, Huang, L, Tortorella, M, Cheng, B, Lee, Y, Qin, D & Li, G 2023, ' Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat-shock protein family ', Bioengineering and Translational Medicine, vol. 8, no. 1, e10354 . https://doi.org/10.1002/btm2.10354
Bioengineering and Translational Medicine, 8(1):e10354. Wiley

The high mortality rate of patients with diabetic foot ulcers is urging the appearance of an effective biomedical drug. Senescence is one of the major reasons of aging-induced decline in the diabetic wound. Our previous studies have demonstrated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70800cf22ee373e723abe6f3849bb7d5
https://doi.org/10.1002/btm2.10354