Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zhisheng, Jia"'
Autor:
Ryosuke Arakawa, Akihiro Takano, Sangram Nag, Zhisheng Jia, Nahid Amini, Kevin P. Maresca, Lei Zhang, Edmund J. Keliher, Christopher R. Butler, Justin R. Piro, Tarek A. Samad, Deborah Smith, Deane Nason, Steve O’Neil, Patrick Trapa, Kari R. Fonseca, John Litchfield, Timothy McCarthy, Richard E. Carson, Christer Halldin
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Background Monoacylglycerol lipase (MAGL) is a key serine hydrolase which terminates endocannabinoid signaling and regulates arachidonic acid driven inflammatory responses within the central nervous system. To develop [11C]PF-06809247 into a
Externí odkaz:
https://doaj.org/article/0b2d2f0ac72047df80a3f5d00a8935c1
Autor:
Sangram Nag, Ryosuke Arakawa, Zhisheng Jia, Erik Lachapelle, Lei Zhang, Kevin Maresca, Laigao Chen, Mahabuba Jahan, Timothy Mccarthy, Christer Halldin
Publikováno v:
Molecules, Vol 28, Iss 12, p 4612 (2023)
Muscarinic acetylcholine receptors (mAChR), including M4, draw attention as therapeutic targets for several neurodegenerative diseases including Alzheimer’s disease (AD). PET imaging of M4 positive allosteric modulator (PAM) allows qualification of
Externí odkaz:
https://doaj.org/article/c786115b08284d89ace0c5db57d9ce81
Autor:
Mahabuba Jahan, Peter Johnström, Ram K. Selvaraju, Marie Svedberg, Maria Sörhede Winzell, Jenny Bernström, Lee Kingston, Magnus Schou, Zhisheng Jia, Stanko Skrtic, Lars Johansson, Olle Korsgren, Lars Farde, Christer Halldin, Olof Eriksson
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Background The G-protein-coupled receptor 44 (GPR44) is a beta cell-restricted target that may serve as a marker for beta cell mass (BCM) given the development of a suitable PET ligand. Methods The binding characteristics of the selected can
Externí odkaz:
https://doaj.org/article/adeebd397411476c89f34e68e0105f08
Autor:
Laetitia Lemoine, Per-Göran Gillberg, Marie Svedberg, Vladimir Stepanov, Zhisheng Jia, Jinghai Huang, Sangram Nag, He Tian, Bernardino Ghetti, Nobuyuki Okamura, Makoto Higuchi, Christer Halldin, Agneta Nordberg
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2017)
Abstract Background The aim of this study was to compare the binding properties of several tau positron emission tomography tracers—THK5117, THK5351, T807 (also known as AV1451; flortaucipir), and PBB3—head to head in the same human brain tissue.
Externí odkaz:
https://doaj.org/article/97991f17d81047ff9c82a76f12203e66
Autor:
Halldin, Sangram Nag, Ryosuke Arakawa, Zhisheng Jia, Erik Lachapelle, Lei Zhang, Kevin Maresca, Laigao Chen, Mahabuba Jahan, Timothy Mccarthy, Christer
Publikováno v:
Molecules; Volume 28; Issue 12; Pages: 4612
Muscarinic acetylcholine receptors (mAChR), including M4, draw attention as therapeutic targets for several neurodegenerative diseases including Alzheimer’s disease (AD). PET imaging of M4 positive allosteric modulator (PAM) allows qualification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::7a42a878861fce78da9bebe28d05575a
Autor:
Yi Li, Zhenyang Liang, Lei Qin, Mian Wang, Xianzhao Wang, Huanyi Zhang, Yin Liu, Yan Li, Zhisheng Jia, Limin Liu, Hongyan Zhang, Jun Luo, Songwu Dong, Jincheng Guo, Hengqing Zhu, Shengli Li, Haijun Zheng, Lijun Liu, Yanqing Wu, Yiming Zhong, Miaohan Qiu, Yaling Han, Gregg W Stone
Publikováno v:
Lancet (London, England). 400(10366)
Previous randomised trials of bivalirudin versus heparin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) have reported conflicting results, in part because of treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdf96f7a62e6f72a41f5aa6fc92bfee
https://pubmed.ncbi.nlm.nih.gov/36351460
https://pubmed.ncbi.nlm.nih.gov/36351460
Autor:
Lars Farde, Christer Halldin, Sangram Nag, Katarina Varnäs, Zhisheng Jia, Sajinder K. Luthra, Rabia Ahmad, Alex Jackson, Marie Svedberg
Publikováno v:
ACS Chemical Neuroscience
Monoamine oxidase B (MAO-B) is an important enzyme regulating the levels of monoaminergic neurotransmitters. Selective MAO-B inhibitors have been labeled with carbon-11 or fluorine-18 to visualize the localization of MAO-B in vivo by positron emissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738513edc43f9b560a32a93776bc2281
http://europepmc.org/articles/PMC7747220
http://europepmc.org/articles/PMC7747220
Autor:
Sangram Nag, Patricia Miranda-Azpiazu, Zhisheng Jia, Prodip Datta, Ryosuke Arakawa, Mohammad Moein, Zhou Yang, Yaoquan Tu, Laetitia Lemoine, Hans Ågren, Agneta Nordberg, Bengt Långström, Christer Halldin
Publikováno v:
ACS Chemical Neuroscience. 13:2932-2933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9cf88cecd5970b1e7a76aade0b90a07
https://doi.org/10.1021/acschemneuro.2c00538
https://doi.org/10.1021/acschemneuro.2c00538
Autor:
Pei Zhang, Manyi Ren, Mei Gao, Yinglong Hou, Liping Ma, Min Zhang, Xiaomeng Jia, Yong Zhang, Jiangrong Wang, Zhisheng Jia
Publikováno v:
Drug Design, Development and Therapy. 14:669-676
Objective This retrospective cohort study is to analyze the impacts of CYP2C19 polymorphism and clopidogrel dosing on in-stent restenosis (ISR) after coronary stenting. Methods Totally, 111 patients were included, who underwent percutaneous coronary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f66ff73134d77e3b3308702f6cbde08
https://doi.org/10.2147/dddt.s242167
https://doi.org/10.2147/dddt.s242167
Autor:
Akihiro Takano, Nahid Amini, Edmund J. Keliher, Christer Halldin, Lei Zhang, Richard E. Carson, Patrick Trapa, Sangram Nag, Ryosuke Arakawa, Deane M. Nason, Kevin P. Maresca, Zhisheng Jia, John Litchfield, Tarek A. Samad, Christopher Ryan Butler, Justin R. Piro, Timothy J. McCarthy, Deborah L. Smith, Steve O’Neil, Kari R. Fonseca
Background Monoacylglycerol lipase (MAGL) is a key serine hydrolase which terminates endocannabinoid signaling and regulates arachidonic acid driven inflammatory responses within the central nervous system. To develop [11C]PF-06809247 into a clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b463c48140050426b0c96d37c2ff81
https://doi.org/10.21203/rs.3.rs-510615/v2
https://doi.org/10.21203/rs.3.rs-510615/v2
