Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Zhiqun Xi"'
Autor:
Seong J. An, Felix Rivera-Molina, Alexander Anneken, Zhiqun Xi, Brian McNellis, Vladimir I. Polejaev, Derek Toomre
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Molecular tethers physically bridge transport vesicles to their target membranes as a prerequisite step for fusion. Here the authors control vesicle tethering using optogenetic approaches to study the interplay between vesicle tethering and fusion.
Externí odkaz:
https://doaj.org/article/eb11223b68d84263b014790f817ad999
Autor:
Lu Ma, Yuhao Kang, Junyi Jiao, Aleksander A. Rebane, Hyo Keun Cha, Zhiqun Xi, Hong Qu, Yongli Zhang
Publikováno v:
Cell Reports, Vol 15, Iss 3, Pp 531-539 (2016)
Intracellular membrane fusion is mediated by dynamic assembly and disassembly of soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein (SNAP) receptors (SNAREs). α-SNAP guides NSF to disassemble SNARE complexes after membrane fusion. Re
Externí odkaz:
https://doaj.org/article/4208b9f7419140b883c7f46f504fa162
Publikováno v:
eLife, Vol 4 (2015)
Synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins couple their stage-wise folding/assembly to rapid exocytosis of neurotransmitters in a Munc18-1-dependent manner. The functions of the different assembly stages i
Externí odkaz:
https://doaj.org/article/6846df68de464a6c820f9fd755435c29
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The phosphoinositide-3 kinase (PI-3K)/AKT cell survival pathway is an important pathway activated by EGFR signaling. Here we show, that in addition to previously described critical components of this pathway, i.e., the docking protein Gab1, the PI-3K
Publikováno v:
Nature chemical biology
We report new lipid-based, high-density, environmentally sensitive (HIDE) probes that accurately and selectively image endo-lysosomes and their dynamics at super-resolution for extended times. Treatment of live cells with the small molecules DiIC16TC
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Primary cilia are slender, cellular antennae that sense extracellular stimuli, and their absence or dysfunction plays a role in numerous human diseases. Prior work has indicated a role of the exocyst tethering complex in cilia biogenesis and maintena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091b587e7b498316d4951d30ffd7a83c
http://hdl.handle.net/10261/260987
http://hdl.handle.net/10261/260987
Autor:
Erdem Karatekin, Zhiqun Xi, Farren J. Isaacs, Derek Toomre, John T. Powell, Julien Berro, Nathan D. Williams, Wenjiao Zhou, Chenxiang Lin, Ane Landajuela, Ravikiran Kasula
Publikováno v:
Nano Lett
Fluorescence microscopy has been one of the most discovery-rich methods in biology. In the digital age, the discipline is becoming increasingly quantitative. Virtually all biological laboratories have access to fluorescence microscopes, but abilities
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background To research the effect of China’s many-child policy on the number of births and the prevalence of serious teratogenic and disabling defects (STDDs) in Hunan province. Methods We performed an observational study based on the Birt
Externí odkaz:
https://doaj.org/article/84e3b0b484ca405f991a40f24c277d34
Autor:
Zippora Shakked, Itai Beno, Zhiqun Xi, Naama Kessler, Tali E. Haran, Varda Rotter, Dmitrij Golovenko, Pratik Vyas, Yan Stein
Publikováno v:
Proceedings of the National Academy of Sciences. 114:10624-10629
The tumor suppressor protein p53 acts as a transcription factor, binding sequence-specifically to defined DNA sites, thereby activating the expression of genes leading to diverse cellular outcomes. Canonical p53 response elements (REs) are made of tw
Autor:
Mitchell H. Omar, Alexander D. Thompson, Derek Toomre, Alanna Schepartz, Anthony J. Koleske, Felix Rivera-Molina, Zhiqun Xi
Publikováno v:
Angewandte Chemie (International ed. in English), vol 56, iss 35
Super-resolution imaging of live cells over extended time periods with high temporal resolution requires high-density labeling and extraordinary fluorophore photostability. Here we achieve this goal by combining the attributes of the high-density pla