Zobrazeno 1 - 10
of 152 511
pro vyhledávání: '"Zhiqiang AN"'
Autor:
Hongying Wang, Lei Wang, Huiwen Luan, Jing Xiao, Zhiling Zhao, Pengfei Yu, Mi Deng, Yifan Liu, Shuhao Ji, Junjie Ma, Yan Zhou, Jiashen Zhang, Xianhui Meng, Juan Zhang, Xinyu Zhao, Chunling Li, Fangmin Li, Dapeng Wang, Shujuan Wei, Lijun Hui, Siman Nie, Changzhu Jin, Zhiqiang An, Ningyan Zhang, Yaopeng Wang, Cheng Cheng Zhang, Zunling Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Leukocyte Ig-like receptor B family 4 (LILRB4) as an immune checkpoint on myeloid cells is a potential target for tumor therapy. Extensive osteolytic bone lesion is the most characteristic feature of multiple myeloma. It is unclea
Externí odkaz:
https://doaj.org/article/adbde63e2cf24b8fa44cd1b4f9eaa095
Autor:
Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P. Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapy such as cisplatin is widely used to treat ovarian cancer either before or after surgical debulking. However, cancer relapse due to chemotherapy resistance is a major challenge in the treatment of ovarian cancer. The underlying m
Externí odkaz:
https://doaj.org/article/ef81d450abe040d3a9700614472c2f15
Autor:
Xiaohua Ye, David J. H. Shih, Zhiqiang Ku, Junping Hong, Diane F. Barrett, Richard E. Rupp, Ningyan Zhang, Tong-Ming Fu, W. Jim Zheng, Zhiqiang An
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Human cytomegalovirus (HCMV) is a leading infectious cause of birth defects and the most common opportunistic infection that causes life-threatening diseases post-transplantation; however, an effective vaccine remains elusive. V160 is a live
Externí odkaz:
https://doaj.org/article/9d0b8d649ccd4ae7bcacc3838138d7ee
Autor:
Manuel A. Riquelme, Xuewei Wang, Francisca M. Acosta, Jingruo Zhang, Jeffery Chavez, Sumin Gu, Peng Zhao, Wei Xiong, Ningyan Zhang, Guo Li, Saranya Srinivasan, Chaoyu Ma, Manjeet K. Rao, Lu-Zhe Sun, Nu Zhang, Zhiqiang An, Jean X. Jiang
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114377- (2024)
Summary: Bone tissue represents the most frequent site of cancer metastasis. We developed a hemichannel-activating antibody, Cx43-M2. Cx43-M2, directly targeting osteocytes in situ, activates osteocytic hemichannels and elevates extracellular ATP, th
Externí odkaz:
https://doaj.org/article/4756bc7168ea467aa3d390ca0185e247
Autor:
Hsuan-Yuan Wang, Leike Li, Cody S. Nelson, Richard Barfield, Sarah Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J. C. Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R. Permar
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Human cytomegalovirus (HCMV) remains the most common congenital infection and infectious complication in immunocompromised patients. The most successful HCMV vaccine to date, an HCMV glycoprotein B (gB) subunit vaccine adjuvanted with MF59,
Externí odkaz:
https://doaj.org/article/585f42ecc487449fb50c16c8c227987f
Autor:
Sarah M. Valencia, Eric Rochat, Melissa J. Harnois, Maria Dennis, Helen S. Webster, Bhavna Hora, Amit Kumar, Hsuan-Yuan (Sherry) Wang, Leike Li, Daniel Freed, Ningyan Zhang, Zhiqiang An, Dai Wang, Sallie R. Permar
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Human Cytomegalovirus (HCMV) is the leading infectious congenital infection globally and the most common viral infection in transplant recipients, therefore identifying a vaccine for HCMV is a top priority. Humoral immunity is a correlate of
Externí odkaz:
https://doaj.org/article/1b2425aaf8034f56a1e1dfae57c8df13
Autor:
Qun Yue, Jie Meng, Yue Qiu, Miaomiao Yin, Liwen Zhang, Weiping Zhou, Zhiqiang An, Zihe Liu, Qipeng Yuan, Wentao Sun, Chun Li, Huimin Zhao, István Molnár, Yuquan Xu, Shuobo Shi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Synthetic biology requires efficient systems that support the well-coordinated co-expression of multiple genes. Here, we discover a 9-bp nucleotide sequence that enables efficient polycistronic gene expression in yeasts and filamentous fungi
Externí odkaz:
https://doaj.org/article/9a3b49ab49ba4accb1800db572381bed
Autor:
Christopher J. LaFargue, Paola Amero, Kyunghee Noh, Lingegowda S. Mangala, Yunfei Wen, Emine Bayraktar, Sujanitha Umamaheswaran, Elaine Stur, Santosh K. Dasari, Cristina Ivan, Sunila Pradeep, Wonbeak Yoo, Chunhua Lu, Nicholas B. Jennings, Vinod Vathipadiekal, Wei Hu, Anca Chelariu-Raicu, Zhiqiang Ku, Hui Deng, Wei Xiong, Hyun-Jin Choi, Min Hu, Takae Kiyama, Chai-An Mao, Rouba Ali-Fehmi, Michael J. Birrer, Jinsong Liu, Ningyan Zhang, Gabriel Lopez-Berestein, Vittorio de Franciscis, Zhiqiang An, Anil K. Sood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Antiangiogenic treatment targeting the vascular endothelial growth factor (VEGF) pathway is a powerful tool to combat tumor growth and progression; however, drug resistance frequently emerges. We identify CD5L (CD5 antigen-like precursor) as
Externí odkaz:
https://doaj.org/article/a4cffeff90ca418b8ed9c213a7bf3531
Autor:
Hailong Guo, Bomsoo Cho, Paul R. Hinton, Sijia He, Yongjun Yu, Ashwin Kumar Ramesh, Jwala Priyadarsini Sivaccumar, Zhiqiang Ku, Kristen Campo, Sarah Holland, Sameer Sachdeva, Christopher Mensch, Mohamed Dawod, Annalis Whitaker, Philip Eisenhauer, Allison Falcone, Rebekah Honce, Jason W. Botten, Stephen F. Carroll, Bruce A. Keyt, Andrew W. Womack, William R. Strohl, Kai Xu, Ningyan Zhang, Zhiqiang An, Sha Ha, John W. Shiver, Tong-Ming Fu
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
The capacity of SARS-CoV-2 to evolve poses challenges to conventional prevention and treatment options such as vaccination and monoclonal antibodies, as they rely on viral receptor binding domain (RBD) sequences from previous strains. Additionally, a
Externí odkaz:
https://doaj.org/article/b32daa709614466280c100d037969216
Publikováno v:
Fermentation, Vol 10, Iss 6, p 311 (2024)
Acetohydroxyacid synthase (AHAS) is a key enzyme in the first step of the branched-chain amino acid synthesis pathway, and the production of acetohydroxybutyrate from one molecule of 2-ketobutyric acid and one molecule of pyruvate. AHAS is inhibited
Externí odkaz:
https://doaj.org/article/d2b56519285e4155867b1f9555ef69b6