Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Zhipeng Zou"'
Autor:
Wenquan Liang, Ru Feng, Xiaojia Li, Xingwei Duan, Shourui Feng, Jun Chen, Yicheng Li, Junqi Chen, Zezheng Liu, Xiaogang Wang, Guangfeng Ruan, Su’an Tang, Changhai Ding, Bin Huang, Zhipeng Zou, Tianyu Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Abnormal subchondral bone remodeling plays a pivotal role in the progression of osteoarthritis (OA). Here, we analyzed subchondral bone samples from OA patients and observed a significant upregulation of ubiquitin carboxy-terminal hydrolase
Externí odkaz:
https://doaj.org/article/f7a7ee020cf3459f9b3c9744966ecd6e
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract During the thermal simulation compression test, the formation of an obvious bulge in the specimen leads to a certain deviation between the calculated and actual values of the true stress. The finite element method was used to simulate the si
Externí odkaz:
https://doaj.org/article/56fbeaec12ac4a10ab3244b1f747427b
Autor:
Ting Wang, Chaoran Zhao, Jiahuan Zhang, Shengfa Li, Youming Zhang, Yan Gong, Yingyue Zhou, Lei Yan, Sheng Zhang, Zhongmin Zhang, Hongling Hu, Anling Liu, Xiaochun Bai, Zhipeng Zou
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108857- (2024)
Summary: The mechanism by which brown adipose tissue (BAT) regulates bone metabolism is unclear. Here, we reveal that BAT secretes S100A8/A9, a previously unidentified BAT adipokine (batokine), to impair bone formation. Brown adipocytes-specific knoc
Externí odkaz:
https://doaj.org/article/7785bfd69b244b379bca64377c2271eb
Autor:
Wenchong Zou, Mingqiang Lai, Yuanjun Jiang, Linlin Mao, Wu Zhou, Sheng Zhang, Pinglin Lai, Bin Guo, Tiantian Wei, Chengtao Nie, Lei Zheng, Jiahuan Zhang, Xuefei Gao, Xiaoyang Zhao, Laixin Xia, Zhipeng Zou, Anling Liu, Shiming Liu, Zhong‐Kai Cui, Xiaochun Bai
Publikováno v:
Advanced Science, Vol 10, Iss 8, Pp n/a-n/a (2023)
Abstract Accumulation of obsolete biomolecules can accelerate cell senescence and organism aging. The two efficient intracellular systems, namely the ubiquitin‐proteasome system and the autophagy‐lysosome system, play important roles in dealing w
Externí odkaz:
https://doaj.org/article/3b0f8b562a7d4b5e96fcedabce77f58f
Autor:
Qiao He, Zhehao Yang, Zhipeng Zou, Mengyan Qian, Xiaolei Wang, Xinhui Zhang, Zhongping Yin, Jinhai Wang, Xingqian Ye, Donghong Liu, Mingming Guo
Publikováno v:
Advanced Science, Vol 10, Iss 6, Pp n/a-n/a (2023)
Abstract The rapid dissemination of antibiotic resistance accelerates the desire for new antibacterial agents. Here, a class of antimicrobial peptides (AMPs) is designed by modifying the structural parameters of a natural chickpea‐derived AMP–Leg
Externí odkaz:
https://doaj.org/article/dcfe773199c54e5fa926473155090087
Autor:
Wei Xia, Jing Xie, Zhiqing Cai, Xuhua Liu, Jing Wen, Zhong-Kai Cui, Run Zhao, Xiaomei Zhou, Jiahui Chen, Xinru Mao, Zhengtao Gu, Zhimin Zou, Zhipeng Zou, Yue Zhang, Ming Zhao, Maegele Mac, Qiancheng Song, Xiaochun Bai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Concomitant traumatic brain injury accelerates bone healing, but the mechanism is unclear. Here, the authors show that injured neurons, mainly those in the hippocampus, release osteogenic miRNA-enriched small extracellular vesicles, which targete ost
Externí odkaz:
https://doaj.org/article/ed80d699848c4bf1a25705f933ee0561
Publikováno v:
Metals, Vol 13, Iss 4, p 696 (2023)
In order to study the metadynamic recrystallization behavior of 34CrNi3MoV steel, a double-pass isothermal compression experiment and a single-pass thermal interval experiment were designed and conducted to obtain the stress–strain curves under dif
Externí odkaz:
https://doaj.org/article/9379a71ba6e7467a88dabb7d9312bd9c
Autor:
Chen Tao, Jia Liu, Ziqi Li, Pinglin Lai, Sheng Zhang, Jiankun Qu, Yujin Tang, Anling Liu, Zhipeng Zou, Xiaochun Bai, Jianwei Li
Publikováno v:
Biology Open, Vol 11, Iss 3 (2022)
The role and underlying mechanisms of DNA methylation in osteogenesis/chondrogenesis remain poorly understood. We here reveal DNA methyltransferase 1 (DNMT1), which is responsible for copying DNA methylation onto the newly synthesized DNA strand afte
Externí odkaz:
https://doaj.org/article/4b7f8545c36747998ef9686ef9fcfa44
Autor:
Wen Liu, Zhenyu Wang, Jun Yang, Yongkui Wang, Kai Li, Bin Huang, Bo Yan, Ting Wang, Mangmang Li, Zhipeng Zou, Jian Yang, Guozhi Xiao, Zhong-Kai Cui, Anling Liu, Xiaochun Bai
Publikováno v:
Open Biology, Vol 9, Iss 5 (2019)
Osteocytes secrete the glycoprotein sclerostin to inhibit bone formation by osteoblasts, but how sclerostin production is regulated in osteocytes remains unclear. Here, we show that tuberous sclerosis complex 1 (TSC1) in osteocytes promotes sclerosti
Externí odkaz:
https://doaj.org/article/9cb149b85f674866be80f3b3b4545d79
Publikováno v:
Applied Sciences, Vol 9, Iss 18, p 3736 (2019)
To provide theoretical basis for cavitation noise control, the cavitation evolution around a hydrofoil and its induced noise were numerically investigated. A modified turbulence model and Zwart cavitation model were employed to calculate the flow fie
Externí odkaz:
https://doaj.org/article/753527c403114aa4961bfd2b6185bb7d