Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Zhimin Long"'
Autor:
Yu Qiu, Yueyang Zhao, Zhimin Long, Aijia Song, Peng Huang, Kejian Wang, Ling Xu, David Paul Molloy, Guiqiong He
Publikováno v:
Genes and Diseases, Vol 10, Iss 1, Pp 284-300 (2023)
Osteoporosis (OP) is a debilitating skeletal abnormality involving bone remodeling and bone cell homeostasis characterized by decreased bone strength and high fracture risk. A novel therapeutic intervention for OP by manipulating cellular autophagy
Externí odkaz:
https://doaj.org/article/d5ec4adb654c40c1b38b85bf3031ea88
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Allergic asthma is a typical chronic inflammatory disease of respiratory tract. Clinical data shows that patients with allergic asthma have different degrees of cognitive dysfunction. The molecular mechanism underlying the pathogenesis of asthma-indu
Externí odkaz:
https://doaj.org/article/ad2b601ffaf94725b69b289d5091db73
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The pathogenesis of Alzheimer’s disease (AD) involves activation of many NLRP3 inflammatory bodies, which may be related to amyloid β peptide and aggregation of misfolded proteins. Autophagy is an important regulator of inflammatory bodies. Howeve
Externí odkaz:
https://doaj.org/article/7c94b3031b2e426abe6ddd8957af6c17
Autor:
Yueyang Zhao, Zhimin Long, Ya Ding, Tingting Jiang, Jiajun Liu, Yimin Li, Yuanjie Liu, Xuehua Peng, Kejian Wang, Min Feng, Guiqiong He
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Dihydroartemisinin (DHA) is an active metabolite of sesquiterpene trioxane lactone extracted from Artemisia annua, which is used to treat malaria worldwide. DHA can activate autophagy, which is the main mechanism to remove the damaged cell components
Externí odkaz:
https://doaj.org/article/1e6a0e2418ed4deea701daa5b4e1d596
Autor:
Qinghua Zeng, Zhimin Long, Min Feng, Yueyang Zhao, Shifang Luo, Kejian Wang, Yingxiong Wang, Guang Yang, Guiqiong He
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Alzheimer’s disease (AD) is an age-related neurodegenerative disease characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFTs) and massive loss of neuronal cells in the brain. Adult hippocampus continuously gen
Externí odkaz:
https://doaj.org/article/62348a0b58b1456f8bc92a159c53cb27
Autor:
Zhimin Long, Chuanhua Ge, Yueyang Zhao, Yuanjie Liu, Qinghua Zeng, Qing Tang, Zhifang Dong, Guiqiong He
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 9, Pp 2633-2644 (2025)
Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-β in neurons, which is a key step in senile plaque formation. Therefore, restoring normal lysosomal function and rebalancing lysosomal
Externí odkaz:
https://doaj.org/article/73770604218842c28056b7c05a1cf27f
Autor:
Peng Huang, David Paul Molloy, Zhimin Long, Yueyang Zhao, Aijia Song, Ling Xu, Kejian Wang, Yu Qiu, Guiqiong He
Publikováno v:
Genes Dis
Osteoporosis (OP) is a debilitating skeletal abnormality involving bone remodeling and bone cell homeostasis characterized by decreased bone strength and high fracture risk. A novel therapeutic intervention for OP by manipulating cellular autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c424defa79f2e4b17728fd0550e87783
https://doi.org/10.1016/j.gendis.2021.06.008
https://doi.org/10.1016/j.gendis.2021.06.008
Autor:
Xiong Su, Songbing He, Xinguo Zhu, Xiaoyan Xu, Zhimin Long, Wei Zhang, Diyuan Zhou, Shugao Yang, Xiangyu Wei, Yizhou Yao, Xiaoheng Huang, Xiaoqin Yang, Liang Sun
Alteration in lipid composition is an important metabolic adaptation by cancer cells to support tumorigenesis and metastasis. Fatty acid 2-hydroxylase (FA2H) introduces a chiral hydroxyl group at the second carbon of fatty acid (FA) backbones and inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c87f1a501412dd86d7b9be2c1ff0a9
https://doi.org/10.1158/0008-5472.c.6512571.v1
https://doi.org/10.1158/0008-5472.c.6512571.v1
Autor:
Xiong Su, Songbing He, Xinguo Zhu, Xiaoyan Xu, Zhimin Long, Wei Zhang, Diyuan Zhou, Shugao Yang, Xiangyu Wei, Yizhou Yao, Xiaoheng Huang, Xiaoqin Yang, Liang Sun
Supplementary Experimental Materials and Methods. Supplementary Figure S1. Expression of FA2H in human colorectal cancer cells. Supplementary Figure S2. siRNA-mediated FA2H knockdown promotes HCT116 cell proliferation and migration. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebf3366efe231a5c347f0835bd3f5ac
https://doi.org/10.1158/0008-5472.22427154.v1
https://doi.org/10.1158/0008-5472.22427154.v1
Autor:
Wei Zhang, Yizhou Yao, Xiaoqin Yang, Xiaoheng Huang, Songbing He, Xiaoyan Xu, Zhimin Long, Xiangyu Wei, Liang Sun, Shugao Yang, Diyuan Zhou, Xiong Su, Xinguo Zhu
Publikováno v:
Cancer Research. 81:289-302
Alteration in lipid composition is an important metabolic adaptation by cancer cells to support tumorigenesis and metastasis. Fatty acid 2-hydroxylase (FA2H) introduces a chiral hydroxyl group at the second carbon of fatty acid (FA) backbones and inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ffa4f5d5ba244c8c2d814b64b50f27
https://doi.org/10.1158/0008-5472.can-20-1517
https://doi.org/10.1158/0008-5472.can-20-1517