Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zhimiao Zou"'
Autor:
Zeyang Li, Minghui Zhao, Xiaoqian Zhang, Yiran Lu, Yang Yang, Yalong Xie, Zhimiao Zou, Liang Zhou, Runshi Shang, Limin Zhang, Fengchao Jiang, Dunfeng Du, Ping Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Cerebral ischemia-reperfusion injury (CIRI) inevitably occurs after vascular recanalization treatment for ischemic stroke. The accompanying inflammatory cascades have a major impact on outcome and regeneration after ischemic stroke. Evide
Externí odkaz:
https://doaj.org/article/54268371274e454eb523743c1e532332
Autor:
Zhimiao Zou, Minghui Zhao, Yang Yang, Yalong Xie, Zeyang Li, Liang Zhou, Runshi Shang, Ping Zhou
Publikováno v:
Cellular Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26c6dcb350599c4df309d9994f2ad4c
https://doi.org/10.1007/s13402-023-00787-9
https://doi.org/10.1007/s13402-023-00787-9
Autor:
Huifang Yang, Ping Zhou, Qingwen Li, Xi Zhou, Junbo Li, Jin Wang, Jingzeng Wang, Yuanyuan Zhao, Bo Yang, Bo Zhang, Chen Dai, Zhimiao Zou, Yang Yang, Zhishui Chen
Publikováno v:
Journal of Cardiovascular Translational Research. 15:1366-1376
Survival of transplanted hearts is often limited by cold ischemia time. Here, we assessed the effects of the small molecular compound TJ-M2010-5 on graft preservation. In a cardiac cold ischemia/reperfusion model, TJ-M2010-5 ameliorated myocardial is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0677abb1fdd4053ae8843694f1a07b51
https://doi.org/10.1007/s12265-022-10246-9
https://doi.org/10.1007/s12265-022-10246-9
Autor:
Zeyang Li, Minghui Zhao, Xiaoqian Zhang, Yiran Lu, Yang Yang, Yalong Xie, Zhimiao Zou, Liang Zhou, Runshi Shang, Limin Zhang, Fengchao Jiang, Dunfeng Du, Ping Zhou
Background: The acute ischemia-reperfusion injury that occurs after an ischemic stroke is almost inevitable. In treating ischemic stroke, the prevention and treatment of cerebral ischemia-reperfusion injury (CIRI) is an undeniable difficulty clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ffb1ee64cb2cb109d68c57a53be6ec
https://doi.org/10.21203/rs.3.rs-1259755/v1
https://doi.org/10.21203/rs.3.rs-1259755/v1
Autor:
Yalong Xie, Dunfeng Du, Limin Zhang, Yang Yang, Zhimiao Zou, Zeyang Li, Liang Zhou, Runshi Shang, Ping Zhou
Publikováno v:
Chemico-biological interactions. 354
Liver fibrosis is the result of most chronic inflammatory liver damage and seriously endangers human health. However, no drugs have been approved to treat this disease. Previous studies showed that the Toll-like receptors (TLRs)/myeloid differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e79130cc863d9c90066d307577153c
https://pubmed.ncbi.nlm.nih.gov/35101388
https://pubmed.ncbi.nlm.nih.gov/35101388
Autor:
Zhimiao, Zou, Zhiheng, Wang
Publikováno v:
Life Sciences. 309:121045
Previous studies have reported that glucagon-like peptide-1 (GLP-1) may play a critical role in the development of intestinal ischemia-reperfusion (I/R) injury. The present study aimed to investigate whether liraglutide (GLP-1 analog) protects agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f01da556bb623e229b0e456dc06757
https://doi.org/10.1016/j.lfs.2022.121045
https://doi.org/10.1016/j.lfs.2022.121045
Autor:
Yalong Xie, Li-Min Zhang, Ping Zhou, Dunfeng Du, Yan Miao, Zeyang Li, Liang Zhou, Yang Yang, Zhimiao Zou, Fengchao Jiang
Publikováno v:
International immunopharmacology. 85
B cell hyperactivities are involved in the development of systemic lupus erythematosus (SLE). Toll-like receptor 7 (TLR7) in the B cells plays a pivotal role in the pathogenesis of SLE. Previous studies have focused on the intrinsic role of B cells i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1bb55326c37a241e519c9a9fbfe833
https://pubmed.ncbi.nlm.nih.gov/32504998
https://pubmed.ncbi.nlm.nih.gov/32504998
Autor:
Xue Zhang, Shuai Xing, Ping Zhou, Long He, Zhimiao Zou, Jianhua Liu, Cheng-Zhi Yi, Lin Xie, Hao Wang, Zuo-Chuan Ding
Publikováno v:
Kidney and Blood Pressure Research. 43:1677-1687
Background/Aims: The TLR/MyD88/NF-κB signaling pathway has been successfully used to treat renal interstitial fibrosis (RIF). However, the exact therapeutic mechanism is still unknown. Here, we assessed the therapeutic efficacy of TJ-M2010-2, a smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93566a69b2fadab3c853cd3a9d05a9ab
https://doi.org/10.1159/000494745
https://doi.org/10.1159/000494745
Autor:
Xue Zhang, Zeyang Li, Chuang Chen, Zhimiao Zou, Shengrong Sun, Weijie Zheng, Ping Zhou, Dong-Cheng Gao, Jian-Hua Liu, Zhi-Hong Sun, Xin-Wen Kuang
Publikováno v:
Experimental Cell Research. 394:112157
MyD88 has been implicated in the tumourigenesis, metastasis and recurrence of breast cancer (BC). Here we utilized TJ-M2010-2 (TJ), an inhibitor of MyD88 homodimerimerization, and siMyD88 to suppress the function of MyD88 in MCF-7 and MDA-MB-231 cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974a13807f0a636c8f97bd9f98336ec1
https://doi.org/10.1016/j.yexcr.2020.112157
https://doi.org/10.1016/j.yexcr.2020.112157
Autor:
Zuochuan Ding, Fengchao Jiang, Xiaoqian Zhang, Yuanyuan Zhao, Zeyang Li, Dunfeng Du, Xinqiang Wang, Yan Miao, Zhimiao Zou, Yang Yang, Jipin Jiang, Min Yang, Xue Zhang, Li-Min Zhang, Ping Zhou
Publikováno v:
International immunopharmacology. 67
Excessive activation of the TLR/MyD88 signaling pathway contributes to several inflammation-related diseases. Previously, our laboratory synthesized a novel thiazaol-aminoramification MyD88 inhibitor named TJ-M2010-5. In this study, we interrogated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57445885d4b6c20e7498f3d856a4e032
https://pubmed.ncbi.nlm.nih.gov/30583234
https://pubmed.ncbi.nlm.nih.gov/30583234