Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zhilou Ding"'
Autor:
Lulu Liu, Lingling Shen, Zhilou Ding, Miao He, En Li, John A. Tallarico, Rishi K. Jain, He Wang
Publikováno v:
ACS Chemical Biology. 18:949-958
Autor:
Lulu Liu, Xin Guo, Yao Wang, Guo Li, Yanyan Yu, Yang Song, Chenhui Zeng, Zhilou Ding, Yuanjun Qiu, Feifei Yan, Yi-Xiang Zhang, Caiqi Zhao, Yan Zhang, Yali Dou, Peter Atadja, En Li, He Wang
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1869(2)
WD repeat domain 5 (WDR5) is a prominent target for pharmacological inhibition in cancer through its scaffolding role with various oncogenic partners such as MLL and MYC. WDR5-related drug discovery efforts center on blocking these binding interfaces
Publikováno v:
Bioorganicmedicinal chemistry. 18(17)
Photodynamic therapy (PDT) represents a promising method for treatment of cancerous tumors. The chemical and physical properties of used photosensitizer play key roles in the treatment efficacy. In this study, a novel photosensitizer, Chlorin-H [-13,